Professor Jorma Ilonen - UTU Research Portal

Jorma Ilonen
Professor

- Senior Advisor,
Institute of Biomedicine (Faculty of Medicine)
- Docent,
Faculty of Medicine (University of Turku)

jsilonen@utu.fi

Kiinamyllynkatu 10

Turku

ORCID identifier: https://orcid.org/0000-0002-9973-2062

Areas of expertise

Immunogenetics

Publications

1 of 18

Characteristics of Type 1 Diabetes Among Patients Carrying the Protective HLA-DQB1*06:02 Allele (2024)
- HLA
Taka, Antti‐Mathias; Härkönen,Taina; Vähäsalo, Paula; Vatanen, Tommi; Lempainen, Johanna; Veijola, Riitta; Turtinen, Maaret; Ilonen, Jorma; Knip, Mikael; the Finnish Pediatric Diabetes Register
(A1 Refereed original research article in a scientific journal)
Distinct cellular immune responses in children en route to type 1 diabetes with different first-appearing autoantibodies (2024)
- Nature Communications
Starskaia Inna, Valta Milla, Pietilä Sami, Suomi Tomi, Pahkuri Sirpa, Kalim Ubaid Ullah, Rasool Omid, Rydgren Emilie, Hyöty Heikki, Knip Mikael, Veijola Riitta, Ilonen Jorma, Toppari Jorma, Lempainen Johanna, Elo Laura L., Lahesmaa Riitta
(A1 Refereed original research article in a scientific journal)
Early‐pregnancy BMI, maternal gestational weight gain, and asthma and allergic diseases in children (2024)
- Pediatric Allergy and Immunology
Ojwang, Vincent; Nwaru, Bright I.; Hanna-Mari, Takkinen; Heli, Tapanainen; Kaila, Minna; Ahonen, Suvi; Niemela, Onni; Haapala, Anna-Maija; Ilonen, Jorma; Toppari, Jorma; Hyoty, Heikki; Veijola, Riitta; Knip, Mikael; Virtanen, Suvi M.
(A1 Refereed original research article in a scientific journal)
Food Consumption and Risk of Islet Autoimmunity and Type 1 Diabetes in Children at Increased Genetic Susceptibility for Type 1 Diabetes (2024)
- Journal of Nutrition
Virtanen, Suvi M; Peltonen, Essi J; Hakola, Leena; Niinistö, Sari; Takkinen, Hanna-Mari; Ahonen, Suvi; Åkerlund, Mari; Uusitalo, Ulla; Mattila, Markus; Salo, Tuuli EI; Ilonen, Jorma; Toppari, Jorma; Veijola, Riitta; Knip, Mikael; Nevalainen, Jaakko
(A1 Refereed original research article in a scientific journal)
Fruit, berry, and vegetable consumption and the risk of islet autoimmunity and type 1 diabetes in children-the Type 1 Diabetes Prediction and Prevention birth cohort study (2024)
- American Journal of Clinical Nutrition
Mattila M, Takkinen HM, Peltonen EJ, Vuorinen AL, Niinistö S, Metsälä J, Ahonen S, Åkerlund M, Hakola L, Toppari J, Ilonen J, Veijola R, Haahtela T, Knip M, Virtanen SM
(A1 Refereed original research article in a scientific journal)
Functional metagenomic analysis reveals potential inflammatory triggers associated with genetic risk for autoimmune disease (2024)
- Journal of Autoimmunity
Berryman, Meghan A.; Ilonen, Jorma; Triplett, Eric W.; Ludvigsson, Johnny

(A1 Refereed original research article in a scientific journal)
Gut inflammation markers, diet, and risk of islet autoimmunity in Finnish children – a nested case-control study (2024)
- Journal of Nutrition
Salo Tuuli E.I., Hakola Leena, Niinistö Sari, Takkinen Hanna-Mari, Ahonen Suvi, Puustinen Leena, Ilonen Jorma, Toppari Jorma, Veijola Riitta, Hyöty Heikki, Knip Mikael, Virtanen Suvi M.
(A1 Refereed original research article in a scientific journal)
Increased Frequency of the HLA-DRB1*04:04-DQA1*03-DQB1*03:02 Haplotype Among HLA-DQB1*06:02-Positive Children With Type 1 Diabetes (2024)
- Diabetes
Ilonen Jorma, Kiviniemi Minna, El-Amir Mostafa I., Nygård Lucas, Härkönen Taina, Lempainen Johanna, Knip Mikael
(A1 Refereed original research article in a scientific journal)
Maternal gluten, cereal, and dietary fiber intake during pregnancy and lactation and the risk of islet autoimmunity and type 1 diabetes in the child (2024)
- Clinical Nutrition ESPEN
Hakola Leena, Lund-Blix Nicolai A., Takkinen Hanna-Mari, Tapanainen Heli, Niinistö Sari, Korhonen Tuuli E., Stene Lars C., Hyöty Heikki, Toppari Jorma, Ilonen Jorma, Knip Mikael, Veijola Riitta, Virtanen Suvi M.; HEDIMED Investigator group
(A1 Refereed original research article in a scientific journal)
Serum proteomics of mother-infant dyads carrying HLA-conferred type 1 diabetes risk (2024)
- iScience
Bhosale, Santosh D.; Moulder, Robert; Suomi, Tomi; Ruohtula, Terhi; Honkanen, Jarno; Virtanen, Suvi M.; Ilonen, Jorma; Elo, Laura L.; Knip, Mikael; Lahesmaa, Riitta
(A1 Refereed original research article in a scientific journal)
Temporal Alterations in CD8+ T Cells During the Progression from Stage 1 to Stage 3 Type 1 Diabetes (2024)
- Diabetes
Schroderus, Anna-Mari; Pitkänen, Viola; Ekman, Ilse; Stevens, Daniella; Rytkönen-Nissinen, Marja; Rintamäki, Reeta; Pihlajamäki, Jussi; Knip, Mikael; Veijola, Riitta; Toppari, Jorma; Ilonen, Jorma; Lempainen, Johanna; Kinnunen, Tuure
(A1 Refereed original research article in a scientific journal)
The effect of early life cytomegalovirus infection on the immune profile of children (2024)
- Clinical Immunology
Ekman, Ilse; Schroderus, Anna-Mari; Vuorinen, Tytti; Knip, Mikael; Veijola, Riitta; Toppari, Jorma; Ilonen, Jorma; Lempainen, Johanna; Kinnunen, Tuure
(A1 Refereed original research article in a scientific journal)
The effect of type 1 diabetes protection and susceptibility associated HLA class II genotypes on DNA methylation in immune cells (2024)
- HLA
Pahkuri, Sirpa; Katayama, Shintaro; Valta, Milla; Nygård, Lucas; Knip, Mikael; Kere, Juha; Ilonen, Jorma; Lempainen, Johanna; Finnish Pediatric Diabetes Register
(A1 Refereed original research article in a scientific journal)
Circulating metabolic signatures of rapid and slow progression to type 1 diabetes in islet autoantibody-positive children (2023)
- Frontiers in Endocrinology
Lamichhane Santosh, Sen Partho, Dickens Alex M, Kråkström Matilda, Ilonen Jorma, Lempainen Johanna, Hyöty Heikki, Lahesmaa Riitta, Veijola Riitta, Toppari Jorma, Hyötyläinen Tuulia, Knip Mikael, Orešič Matej

(A1 Refereed original research article in a scientific journal)
CXADR polymorphism rs6517774 modifies islet autoimmunity characteristics and exhibits sex disparity (2023)
- Frontiers in Genetics
Nygård Lucas, Valta Milla, Laine Antti-Pekka, Toppari Jorma, Knip Mikael, Veijola Riitta, Hyöty Heikki, Ilonen Jorma, Lempainen Johanna
(A1 Refereed original research article in a scientific journal)
Dietary fatty acid intake in childhood and the risk of islet autoimmunity and type 1 diabetes: the DIPP birth cohort study (2023)
- European Journal of Nutrition
Hakola Leena, Vuorinen Anna-Leena, Takkinen Hanna-Mari, Niinistö Sari, Ahonen Suvi, Rautanen Jenna, Peltonen Essi J, Nevalainen Jaakko, Ilonen Jorma, Toppari Jorma, Veijola Riitta, Knip Mikael, Virtanen Suvi M
(A1 Refereed original research article in a scientific journal)
DNA methylation differences within INS, PTPN22 and IL2RA promoters in lymphocyte subsets in children with type 1 diabetes and controls (2023)
- Autoimmunity
Pahkuri Sirpa, Ekman Ilse, Vandamme Céline, Näntö-Salonen Kirsti, Toppari Jorma, Veijola Riitta, Knip Mikael, Kinnunen Tuure, Ilonen Jorma, Lempainen Johanna
(A1 Refereed original research article in a scientific journal)
Evaluation of plasma IL-21 as a potential biomarker for type 1 diabetes progression (2023)
- Frontiers in Immunology
Schroderus Anna-Mari, Poorbaugh Josh, McElyea Samantha, Beasley Stephanie, Zhang Lin, Näntö-Salonen Kirsti, Rintamäki Reeta, Pihlajamäki Jussi, Knip Mikael, Veijola Riitta, Toppari Jorma, Ilonen Jorma, Benschop Robert J., Kinnunen Tuure
(A1 Refereed original research article in a scientific journal)
Extremely Early Appearance of Islet Autoantibodies in Genetically Susceptible Children (2023)
- Pediatric Diabetes
Kyrönniemi Anni, Valtanen Toni, Koskenniemi Jaakko, Vähäsalo Paula, Härkönen Taina, Ilonen Jorma, Toppari Jorma, Knip Mikael, Veijola Riitta
(A1 Refereed original research article in a scientific journal)
Finnish children carrying the high-risk HLA genotype have a 45-fold increased risk of type 1 diabetes compared to peers with neutral or protective genotypes (2023)
- Diabetes Research and Clinical Practice
Taka Antti-Mathias, But Anna, Lempainen Johanna, Vatanen Tommi, Härkönen Taina, Ilonen Jorma, Knip Mikael
(A1 Refereed original research article in a scientific journal)