Ph.D. dos Jarmo Käpylä - UTU Research Portal

Jarmo Käpylä
Ph.D. dos

- University Lecturer,
Biochemistry (Department of Life Technologies)

jakapy@utu.fi

+358 29 450 4704

+358 40 191 1153

Tykistökatu 6

Turku

ORCID identifier: https://orcid.org/0000-0003-3036-713X(external)

Areas of expertise

Protein structure and function

Research

Extracellular matrix, integrins

Teaching

Lectures: Molecular biology, Proteins

Lab courses: Molecular biology techniques, Protein techniques

Publications

1 of 2

Collagen prolyl 4-hydroxylase isoenzymes I and II have sequence specificity towards different X-Pro-Gly triplets (2024)
- Matrix Biology
Salo Antti M., Rappu Pekka, Koski M．Kristian, Karjalainen Emma, Izzi Valerio, Drushinin Kati, Miinalainen Ilkka, Käpylä Jarmo, Heino Jyrki, Myllyharju Johanna
(A1 Refereed original research article in a scientific journal)
Exploring the Interactions between Plant Proanthocyanidins and Thiabendazole : Insights from Isothermal Titration Calorimetry (2024)
- Molecules
Sillanpää, Mimosa; Engström, Marica T.; Tähtinen, Petri; Green, Rebecca J.; Käpylä, Jarmo; Näreaho, Anu; Karonen, Maarit
(A1 Refereed original research article in a scientific journal)
Tannins Can Have Direct Interactions with Anthelmintics: Investigations by Isothermal Titration Calorimetry (2023)
- Molecules
Sillanpää Mimosa, Engström Marica T.,Tähtinen Petri, Green Rebecca J., Käpylä Jarmo, Näreaho Anu, Karonen Maarit
(A1 Refereed original research article in a scientific journal)
Embigin is a fibronectin receptor that affects sebaceous gland differentiation and metabolism (2022)
- Developmental Cell
Sipilä Kalle, Rognoni Emanuel, Jokinen Johanna, Tewary Mukul, Rudan Matteo Vietri, Talvi Salli, Jokinen Ville, Dahlström Käthe M, Liakath-Ali Kif, Mobasseri Atefeh, Du-Harpur Xinyi, Käpylä Jarmo, Nutt Stephen L, Salminen Tiina A, Heino Jyrki, Watt Fiona M
(A1 Refereed original research article in a scientific journal)
Integrin alpha 11 beta 1 is a receptor for collagen XIII (2020)
- Cell and Tissue Research
Koivunen J, Tu H, Kemppainen A, Anbazhagan P, Finnila MA, Saarakkala S, Kapyla J, Lu N, Heikkinen A, Juffer AH, Heino J, Gullberg D, Pihlajaniemi T
(A1 Refereed original research article in a scientific journal)
The binding mechanism of adhesin P subtype to globotetraosylceramide is associated with systemic disease (2020)
- Journal of Biological Chemistry
Johansson MM, Bélurier E, Papageorgiou AC, Sundin AP, Rahkila J, Kallonen T, Nilsson UJ, Maatsola S, Nyholm TKM, Käpylä J, Corander J, Leino R, Finne J, Teneberg S, Haataja S
(A1 Refereed original research article in a scientific journal)
Proline hydroxylation in collagen supports integrin binding by two distinct mechanisms (2018)
- Journal of Biological Chemistry
Kalle H. Sipilä, Kati Drushinin, Pekka Rappu, Johanna Jokinen, Tiina A. Salminen, Antti M. Salo, Jarmo Käpylä, Johanna Myllyharju, Jyrki Heino
(A1 Refereed original research article in a scientific journal)
Joint inflammation related citrullination of functional arginines in extracellular proteins (2017)
- Scientific Reports
Sipila KH, Ranga V, Rappu P, Mali M, Pirila L, Heino I, Jokinen J, Kapyla J, Johnson MS, Heino J
(A1 Refereed original research article in a scientific journal)
The binding capacity of alpha 1 beta 1-, alpha 2 beta 1-and alpha 10 beta 1-integrins depends on non-collagenous surface macromolecules rather than the collagens in cartilage fibrils (2017)
- Matrix Biology
Woltersdorf C, Bonk M, Leitinger B, Huhtala M, Kapyla J, Heino J, Girol CG, Niland S, Eble JA, Bruckner P, Dreier R, Hansen U
(A1 Refereed original research article in a scientific journal)
Extracellular citrullination inhibits the function of matrix associated TGF-beta (2016)
- Matrix Biology
Sipila KH, Ranga V, Rappu P, Torittu A, Pirila L, Kapyla J, Johnson MS, Larjava H, Heino J
(A1 Refereed original research article in a scientific journal)
Sulfonamide inhibitors of α2β1 integrin reveal the essential role of collagen receptors in in vivo models of inflammation. (2015)
- Pharmacology Research and Perspectives
Nissinen L, Ojala M, Langen B, Dost R, Pihlavisto M, Käpylä J, Marjamäki A, Heino J.
(A1 Refereed original research article in a scientific journal)
Citrullination of collagen II affects integrin-mediated cell adhesion in a receptor-specific manner. (2014)
- FASEB Journal
Kalle Sipilä, Sabrina Haag, Konstantin Denessiouk, Jarmo Käpylä, Eric C. Peters, Alexander Denesyuk, Uwe Hansen, Yrjö Konttinen, Mark S. Johnson, Rikard Holmdahl, Jyrki Heino
(A1 Refereed original research article in a scientific journal)
Early Chordate Origin of the Vertebrate Integrin αI Domains (2014)
- PLoS ONE
Bhanupratap Singh Chouhan,Jarmo Käpylä,Konstantin Denessiouk, Alexander Denesyuk,Jyrki Heino,Mark S. Johnson
(A1 Refereed original research article in a scientific journal)
In vitro blood and fibroblast responses to BisGMA-TEGDMA/bioactive glass composite implants. (2014)
- Journal of Materials Science: Materials in Medicine
Abdulmajeed AA, Kokkari AK, Kapyla J, Massera J, Hupa L, Vallittu PK, Närhi TO
(A1 Refereed original research article in a scientific journal)
Evolution of Cell Adhesion to Extracellular Matrix (2013) Evolution of Extracellular Matrix Johnson MS, Kapyla J, Denessiouk K, Airenne T, Chouhan BS, Heino J
(A3 Refereed book chapter or chapter in a compilation book)
Leukocyte integrins alpha(L)beta(2), alpha(M)beta(2) and alpha(X)beta(2) as collagen receptors - Receptor activation and recognition of GFOGER motif (2013)
- International Journal of Biochemistry and Cell Biology
Lahti M, Heino J, Kapyla J
(A1 Refereed original research article in a scientific journal)
Molecular mechanism of T-cell protein tyrosine phosphatase (TCPTP) activation by mitoxantrone (2013)
- BBA - Biochimica et Biophysica Acta
Mikko Ylilauri, Elina Mattila, Elisa M Nurminen, Jarmo Käpylä, Sanna P Niinivehmas, Juha A Määttä, Ulla Pentikäinen, Johanna Ivaska, and Olli T Pentikäinen
(A1 Refereed original research article in a scientific journal)
Novel alpha 2 beta 1 Integrin Inhibitors Reveal That Integrin Binding to Collagen under Shear Stress Conditions Does Not Require Receptor Preactivation (2012)
- Journal of Biological Chemistry
Nissinen L, Koivunen J, Käpylä J, Salmela M, Nieminen J, Jokinen J, Sipilä K, Pihlavisto M, Pentikäinen OT, Marjamäki A, Heino J
(A1 Refereed original research article in a scientific journal)
Collagen XXIII, Novel Ligand for Integrin alpha(2)beta(1) in the Epidermis (2011)
- Journal of Biological Chemistry
Veit G, Zwolanek D, Eckes B, Niland S, Kapyla J, Zweers MC, Ishada-Yamamoto A, Krieg T, Heino J, Eble JA, Koch M
(A1 Refereed original research article in a scientific journal)
Fluorescent Small Molecule Probe to Modulate and Explore alpha 2 beta 1 Integrin Function (2011)
- Journal of the American Chemical Society
Koivunen JT, Nissinen L, Kapyla J, Jokinen J, Pihlavisto M, Marjamaki A, Heino J, Huuskonen J, Pentikainen OT
(A1 Refereed original research article in a scientific journal)