Jeroen Pouwels
jeroen.pouwels@utu.fi +358 29 450 3786 Tykistökatu 6 Turku |
- Ovarian Cancers with Low CIP2A Tumor Expression Constitute an APR-246-Sensitive Disease Subtype (2022)
- Molecular Cancer Therapeutics
- SHARPIN S146 phosphorylation mediates ARP2/3 interaction, cancer cell invasion and metastasis (2022)
- Journal of Cell Science
- Integrin beta 1 inhibition alleviates the chronic hyperproliferative dermatitis phenotype of SHARPIN-deficient mice (2017)
- PLoS ONE
- The Sharpin interactome reveals a role for Sharpin in lamellipodium formation via the Arp2/3 complex (2017)
- Journal of Cell Science
- Phosphorylation of Sharpin acts as a molecular switch to control Linear Ubiquitination Assembly Complex (LUBAC) and Arp2/3 function (2016)
- Molecular Biology of the Cell
- Selective integrin endocytosis is driven by interactions between the integrin α-chain and AP2 (2016)
- Nature Structural and Molecular Biology
- Formin-like 2 Promotes beta 1-Integrin Trafficking and Invasive Motility Downstream of PKC alpha (2015)
- Developmental Cell
- Mutually Exclusive Roles of SHARPIN in Integrin Inactivation and NF-κB Signaling (2015)
- PLoS ONE
- A ZO-1/alpha 5 beta 1-Integrin Complex Regulates Cytokinesis Downstream of PKC epsilon in NCI-H460 Cells Plated on Fibronectin (2013)
- PLoS ONE
- Integrin inactivators: balancing cellular functions in vitro and in vivo (2013)
- Nature Reviews Molecular Cell Biology
- Novel pyrimidine-2,4-diamine derivative suppresses the cell viability and spindle assembly checkpoint activity by targeting Aurora kinases (2013)
- Carcinogenesis
- SHARPIN Regulates Uropod Detachment in Migrating Lymphocytes (2013)
- Cell Reports
- Negative regulators of integrin activity (2012)
- Journal of Cell Science
- The flavonoid eupatorin inactivates the mitotic checkpoint leading to polyploidy and apoptosis (2012)
- Experimental Cell Research
- High frequency of TTK mutations in microsatellite-unstable colorectal cancer and evaluation of their effect on spindle assembly checkpoint (2011)
- Carcinogenesis
- Loss of p38 gamma MAPK induces pleiotropic mitotic defects and massive cell death (2011)
- Journal of Cell Science
- SHARPIN is an endogenous inhibitor of beta 1-integrin activation (2011)
- Nature Cell Biology
- Spatio-temporal composition of the mitotic Chromosomal Passenger Complex detected using in situ proximity ligation assay (2011)
- Molecular Oncology
- Perturbation of Incenp function impedes anaphase chromatid movements and chromosomal passenger protein flux at centromeres (2009)
- Chromosoma
- Shugoshin 1 plays a central role in kinetochore assembly and is required for kinetochore targeting of Plk1 (2007)
- Cell Cycle
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