Pirkko Heikinheimo

- Teacher,
Department of Teacher Education (Turku) (Department of Teacher Education)
- Docent,
Faculty of Science (University of Turku)

Department of Biochemistry and Turun Normaalikoulu

pirkko.heikinheimo@utu.fi

Tykistökatu 6

Turku

Office: B205

Publications

1 of 2

amamutdb.no: A Relational Database for MAN2B1 Allelic Variants that Compiles Genotypes, Clinical Phenotypes, and Biochemical and Structural Data of Mutant MAN2B1 in -Mannosidosis (2015)
- Human Mutation
Stensland HMFR, Frantzen G, Kuokkanen E, Buvang EK, Klenow HB, Heikinheimo P, Malm D, Nilssen O
(A1 Refereed original research article in a scientific journal)
Is the Bovine lysosomal phospholipase B like protein an amidase? (2014)
- Proteins
Heidi Repo, Elina Kuokkanen, Esko Oksanen, Adrian Goldman, Pirkko Heikinheimo
(A1 Refereed original research article in a scientific journal)
Autosomal Dominant Diabetes Arising From a Wolfram Syndrome 1 Mutation (2013)
- Diabetes
Bonnycastle LL, Chines PS, Hara T, Huyghe JR, Swift AJ, Heikinheimo P, Mahadevan J, Peltonen S, Huopio H, Nuutila P, Narisu N, Goldfeder RL, Stitzel ML, Lu SM, Boehnke M, Urano F, Collins FS, Laakso M
(A1 Refereed original research article in a scientific journal)
A monomeric TIM-barrel structure from Pyrococcus furiosus is optimized for extreme temperatures (2012)
- Acta Crystallographica Section D: Biological Crystallography
Repo H, Oeemig JS, Djupsjobacka J, Iwai H, Heikinheimo P
(A1 Refereed original research article in a scientific journal)
Systematic Structure-Activity Study on Potential Chaperone Lead Compounds for Acid alpha-Glucosidase (2012)
- ChemMedChem
Bruckmann C, Repo H, Kuokkanen E, Xhaard H, Heikinheimo P
(A1 Refereed original research article in a scientific journal)
Molecular and cellular characterization of novel alpha-mannosidosis mutations (2011)
- Human Molecular Genetics
Kuokkanen E, Stensland HMFR, Smith W, Buvang EK, Nguyen L, Nilssen Ø, Heikinheimo P
(A1 Refereed original research article in a scientific journal)
Overexpression of Man2C1 leads to protein underglycosylation and upregulation of endoplasmic reticulum-associated degradation pathway (2011)
- Glycobiology
Bernon C, Carre Y, Kuokkanen E, Slomianny MC, Mir AM, Krzewinski F, Cacan R, Heikinheimo P, Morelle W, Michalski JC, Foulquier F, Duvet S
(A1 Refereed original research article in a scientific journal)
Coordination sphere of the third metal site is essential to the activity and metal selectivity of alkaline phosphatases (2010)
- Protein Science
Koutsioulis D, Lyskowski A, Mäki S, Guthrie E, Feller G, Bouriotis V, Heikinheimo P
(A1 Refereed original research article in a scientific journal)
Directed evolution on the cold adapted properties of TAB5 alkaline phosphatase (2008)
- Protein Engineering, Design and Selection
Koutsioulis D, Wang E, Tzanodaskalaki M, Nikiforaki D, Deli A, Feller G, Heikinheimo P, Bouriotis V
(A1 Refereed original research article in a scientific journal)
A complete structural description of the catalytic cycle of yeast pyrophosphatase (2007) Oksanen E, Ahonen AK, Tuominen H, Tuominen V, Lahti R, Goldman A, Heikinheimo P
(A1 Refereed original research article in a scientific journal)
Characterisation and subcellular localisation of human neutral class II alfa-mannosidase (2007)
- Glycobiology
Elina Kuokkanen, Wesley Smith, Marika Mäkinen, Heidi Tuominen, Maija Puhka, Eija Jokitalo, Ole-Kristian Tollersrud, Rene Cacan, Sandrine Duvet, Thomas Berg, Pirkko Heikinheimo
(A1 Refereed original research article in a scientific journal)
Comparative expression study to increase the solubility of cold adapted Vibrio proteins in Escherichia coli (2007)
- Protein Expression and Purification
Niiranen L, Espelid S, Karlsen CR, Mustonen M, Paulsen SM, Heikinheimo P, Willassen NP
(A1 Refereed original research article in a scientific journal)
Crystal structure of alkaline phosphatase from the Antarctic bacterium TAB5 (2007) Wang E, Koutsioulis D, Leiros HKS, Andersen OA, Bouriotis V, Hough E, Heikinheimo P
(A1 Refereed original research article in a scientific journal)
Funtional characterization of four novel MAN2B1 mutations causing juvenile onset alpha-mannosidosis (2007)
- Clinica Chimica Acta
Pittis MG, Montalvo ALE, Heikinheimo P, Sbaragli M, Balducci C, Persichetti E, Van Maldergem L, Filocamo M, Bembi B, Beccari T
(A1 Refereed original research article in a scientific journal)
The 2.1 Å structure of Aerococcus viridans L-lactate oxidase (LOX) (2006)
- Acta Crystallographica Section F: Structural Biology and Crystallization Communications
Leiros I, Wang E, Rasmussen T, Oksanen E, Repo H, Petersen SB, Heikinheimo P, Hough E
(A1 Refereed original research article in a scientific journal)
Identification and Characterisation of Novel Mutations in Italian Patients with alpha-Mannosidosis (2005)
- Human Mutation
Sbaragli M, Bibi L, Pittis G, Balducci C, Heikinheimo P, Ricci R, Antuzzi D, Parini R, Spaccini L, Bembi B, Beccari T
(A1 Refereed original research article in a scientific journal)
Intracellular transport of human lysosomal alpha-mannosidase and alpha-mannosidosis-related mutants (2004)
- Biochemical Journal
Hansen G, Berg T, Stensland HMFR, Heikinheimo P, Klenow H, Evjen G, Nilssen O, Tollersrud OK
(A1 Refereed original research article in a scientific journal)
Production and preliminary analysis of perdeuterated yeast inorganic pyrophosphatase crystals suitable for neutron diffraction (2004)
- Acta Crystallographica Section D: Biological Crystallography
Tuominen VU, Myles DAA, Dauvergne MT, Lahti R, Heikinheimo P, Goldman A
(A1 Refereed original research article in a scientific journal)
Downstream coding region determinants of bacterio-opsin, muscarinic acetylcholine receptor and adrenergic receptor expression in Halobacterium salinarum (2003)
- BBA - Biomembranes
Bartus CL, Jaakola VP, Reusch R, Valentine HH, Heikinheimo P, Levay A, Potter LT, Heimo H, Goldman A, Turner GJ
(A1 Refereed original research article in a scientific journal)
Structure of the bovine lysosomal α-mannosidase, the enzyme involved in the lysosomal storage disease alpha-mannosidosis (2003)
- ESRF HIghlights
ESRF Highlights 2002 Heikinheimo P, Helland R, Schrøder-Leiros H-K, Leiros I, Karlsen S, Evjen G, Ravelli R, Schoehn G, Ruigrok R, Tollersrud O-K, McSweeney S, Hough E
(A4 Refereed article in a conference publication )