Semi Helin - UTU Research Portal - UTU Research Portal

Semi Helin

- Senior Researcher,
Turku PET Centre (Independent units)

semhel@utu.fi

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Insulin resistance and body mass index are associated with TSPO PET in cognitively unimpaired elderly (2023)
- Journal of Cerebral Blood Flow and Metabolism
Ekblad Laura L, Tuisku Jouni, Koivumäki Mikko, Helin Semi, Rinne Juha O, Snellman Anniina
Direct Comparison of [18F]F-DPA with [18F]DPA-714 and [11C]PBR28 for Neuroinflammation Imaging in the same Alzheimer’s Disease Model Mice and Healthy Controls (2022)
- Molecular Imaging and Biology
López-Picón Francisco R, Keller Thomas, Bocancea Diana, Helin Jatta S, Krzyczmonik Anna, Helin Semi, Damont Annelaure, Dollé Frédéric, Rinne Juha O, Haaparanta-Solin Merja, Solin Olof
Obesity risk is associated with altered cerebral glucose metabolism and decreased μ-opioid and CB1 receptor availability (2022)
- International Journal of Obesity
Kantonen Tatu, Pekkarinen Laura, Karjalainen Tomi, Bucci Marco, Kalliokoski Kari, Haaparanta-Solin Merja, Aarnio Richard, Dickens Alex M., von Eyken Annie, Laitinen Kirsi, Houttu Noora, Kirjavainen Anna K., Helin Semi, Hirvonen Jussi, Rönnemaa Tapani, Nuutila Pirjo, Nummenmaa Lauri
Association of Early β-Amyloid Accumulation and Neuroinflammation Measured With [11C]PBR28 in Elderly Individuals Without Dementia (2021)
- Neurology
Toppala Sini, Ekblad Laura L., Tuisku Jouni, Helin Semi, Johansson Jarkko J., Laine Hanna, Löyttyniemi Eliisa, Marjamäki Päivi, Blennow Kaj, Zetterberg Henrik, Jula Antti, Viitanen Matti, Rinne Juha O.
Comparison of: (2S,4R)-4-[F-18]Fluoroglutamine, [C-11]Methionine, and 2-Deoxy-2-[F-18]Fluoro-D-Glucose and Two Small-Animal PET/CT Systems Imaging Rat Gliomas (2021)
- Frontiers in Oncology
Miner Maxwell WG, Liljenbäck Heidi, Virta Jenni, Helin Semi, Eskola Olli, Elo Petri, Teuho Jarmo, Seppälä Kerttu, Oikonen Vesa, Yang Guangli, Kindler-Röhrborn Andrea, Minn Heikki, Li Xiang-Guo, Roivainen Anne
Effect of dopaminergic medication on adenosine 2A receptor availability in patients with Parkinson's disease (2021)
- Parkinsonism and Related Disorders
Waggan Imran, Rissanen Eero, Tuisku Jouni, Matilainen Markus, Helin Semi, Parkkola Riitta, Rinne Juha O., Airas Laura
Episodic memory and cortical amyloid pathology: PET study in cognitively discordant twin pairs (2021)
- Neurobiology of Aging
Lindgren Noora, Kaprio Jaakko, Karjalainen Tomi, Ekblad Laura, Helin Semi, Karrasch Mira, Teuho Jarmo, Rinne Juha O, Vuoksimaa Eero
Mesolimbic opioid-dopamine interaction is disrupted in obesity but recovered by weight loss following bariatric surgery (2021)
- Translational Psychiatry
Karlsson Henry K, Tuominen Lauri, Helin Semi, Salminen Pauliina, Nuutila Pirjo, Nummenmaa Lauri
Preoperative brain μ-opioid receptor availability predicts weight development following bariatric surgery in women (2021)
- JCI Insight
Karlsson Henry K, Tuominen Lauri, Helin Semi, Salminen Paulina, Nuutila Pirjo, Nummenmaa Lauri
Response to letter on use of functional imaging by 11C-metomidate PET for primary aldosteronism subtyping (2021)
- European Journal of Endocrinology
Soinio Minna, Luukkonen Anna-Kaarina, Seppänen Marko, Kemppainen Jukka, Seppänen Janne, Pienimäki Juha-Pekka, Leijon Helena, Vesterinen Tiina, Arola Johanna, Lantto Eila, Helin Semi, Tikkanen Ilkka, Metso Saara, Mirtti Tuomas, Heiskanen Ilkka, Norvio Leena, Tiikkainen Mirja, Tikkanen Tuula, Sane Timo, Välimäki Matti, Gomez-Sanchez Celso E, Pörsti Ilkka, Nuutila Pirjo, Nevalainen Pasi I, Matikainen Niina
Seasonal variation in the brain μ-opioid receptor availability (2021)
- Journal of Neuroscience
Sun Lihua, Tang Jing, Liljenbäck Heidi, Honkaniemi Aake, Virta Jenni, Isojärvi Janne, Karjalainen Tomi, Kantonen Tatu, Nuutila Pirjo, Hietala Jarmo, Kaasinen Valtteri, Kalliokoski Kari, Hirvonen Jussi, Scheinin Harry, Helin Semi, Eerola Kim, Savontaus Eriika, Yatkin Emrah, Rinne Juha O, Roivainen Anne, Nummenmaa Lauri
Association of neuroinflammation with episodic memory: a [11C]PBR28 PET study in cognitively discordant twin pairs (2020)
- Brain Communications
Noora Lindgren, Jouni Tuisku, Eero Vuoksimaa, Semi Helin, Mira Karrasch, Päivi Marjamäki, Jaakko Kaprio, Juha O Rinne
Decreased Availability of Adenosine 2A Receptors in the Caudate in Patients with Early Stage Parkinson’s Disease (2020)
- Movement Disorders
Imran Waggan, Eero Rissanen, Jouni Tuisku, Juho Joutsa, Semi Helin, Riitta Parkkola, Juha O. Rinne, Laura Airas
Effect of Dopaminergic Medication on Adenosine 2A Receptor Availability in Patients with Parkinson’s Disease (2020) Imran Waggan, Jouni Tuisku, Markus Matilainen, Semi Helin, Riitta Parkkola, Eero Rissanen, Juha Rinne, Laura Airas,
Elevated serum chemokine CCL22 levels in first-episode psychosis: associations with symptoms, peripheral immune state and in vivo brain glial cell function (2020)
- Translational Psychiatry
Heikki Laurikainen, Arja Vuorela, Anna Toivonen, Linnea Reinert-Hartwall, Kalevi Trontti, Maija Lindgren, Jaakko Keinänen, Teemu Mäntylä, Janina Paju, Tuula Ilonen, Reetta-Liina Armio, Maija Walta, Jouni Tuisku, Semi Helin, Päivi Marjamäki, Iiris Hovatta, Sebastian Therman, Outi Vaarala, Outi Linnaranta, Tuula Kieseppä, Raimo K. R. Salokangas, Jarno Honkanen, Jarmo Hietala, Jaana Suvisaari
Functional imaging with C-11-metomidate PET for subtype diagnosis in primary aldosteronism (2020)
- European Journal of Endocrinology
Minna Soinio, Anna-Kaarina Luukkonen, Marko Seppänen, Jukka Kemppainen, Janne Seppänen, Juha-Pekka Pienimäki, Helena Leijon , Tiina Vesterinen, Johanna Arola, Eila Lantto, Semi Helin, Ilkka Tikkanen, Saara Metso, Tuomas Mirtti, Ilkka Heiskanen, Leena Norvio, Mirja Tiikkainen, Tuula Tikkanen, Timo Sane, Matti Välimäki, Celso E Gomez-Sanchez, Ilkka Pörsti, Pirjo Nuutila, Pasi I Nevalainen, Niina Matikainen
68Ga-DOTA chelate, a novel imaging agent for assessment of myocardial perfusion and infarction detection in a rodent model (2019)
- Journal of Nuclear Cardiology
Anu Autio, Sauli Uotila, Max Kiugel, Ville Kytö, Heidi Liljenbäck, Nobuyuki Kudomi, Vesa Oikonen, Olli Metsälä, Semi Helin, Juhani Knuuti, Antti Saraste, Anne Roivainen
Brain beta-Amyloid and Atrophy in Individuals at Increased Risk of Cognitive Decline (2019)
- American Journal of Neuroradiology
Martikainen IK, Kemppainen N, Johansson J, Teuho J, Helin S, Liu Y, Helisalmi S, Soininen H, Parkkola R, Ngandu T, Kivipelto M, Rinne JO
Effects of age, BMI and sex on the glial cell marker TSPO - a multicentre [C-11]PBR28 HRRT PET study (2019)
- European Journal of Nuclear Medicine and Molecular Imaging
Tuisku J, Plaven-Sigray P, Gaiser EC, Airas L, Al-Abdulrasul H, Bruck A, Carson RE, Chen MK, Cosgrove KP, Ekblad L, Esterlis I, Farde L, Forsberg A, Halldin C, Helin S, Kosek E, Lekander M, Lindgren N, Marjamaki P, Rissanen E, Sucksdorff M, Varrone A, Collste K, Gallezot JD, Hillmer A, Huang YY, Hoglund CO, Johansson J, Jucaite A, Lampa J, Nabulsi N, Pittman B, Sandiego CM, Stenkrona P, Rinne J, Matuskey D, Cervenka S
Folate receptor-targeted positron emission tomography of experimental autoimmune encephalomyelitis in rats (2019)
- Journal of Neuroinflammation
Elo P, Li X-G, Liljenback H, Helin S, Teuho J, Koskensalo K, Saunavaara V, Marjamäki P, Oikonen V, Virta J, Chen Q, Low PS, Knuuti J, Jalkanen S, Airas L, Roivainen A