Semi Helin - UTU Research Portal - UTU Research Portal

Semi Helin

- Doctoral Researcher,
Imaging and Clinical Diagnostics (Department of Clinical Medicine)
- Senior Researcher,
Turku PET Centre (Independent units)

semhel@utu.fi

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Obesity is associated with increased brain glucose uptake and activity but not neuroinflammation (TSPO availability) in monozygotic twin pairs discordant for BMI—Exercise training reverses increased brain activity (2025)
- Diabetes, Obesity and Metabolism
Hentilä, Jaakko; Tuisku, Jouni; Ojala, Ronja; Sun, Lihua; Lietzén, Martin S.; Virtanen, Heidi; Lautamäki, Riikka; Koskensalo, Kalle; Nummenmaa, Lauri; Löyttyniemi, Eliisa; Helin, Semi; Pietiläinen, Kirsi H.; Kaprio, Jaakko; Lahti, Leo; Malm, Tarja; Rinne, Juha O.; Hannukainen, Jarna C.
Progression of Amyloid Accumulation in Late Adulthood Among People With Childhood-Onset Epilepsy (2025)
- Neurology
Joutsa, Juho; Rinne, Juha O.; Niemi, Kalle J.; Karrasch, Mira; Parkkola, Riitta K.; Saunavaara, Jani; Helin, Semi P.; Hermann, Bruce P.; Sillanpää, Matti
Striatal cue-reactivity and neurotransmitter function in gambling disorder (2025)
- Journal of behavioral addictions
Bellmunt-Gil, Albert; Majuri, Joonas; Nummenmaa, Lauri; Helin, Semi; Forsback, Sarita; Rajander, Johan; Kaasinen, Valtteri; Joutsa, Juho
Aberrant type 2 dopamine receptor availability in violent offenders with psychopathy (2024)
- NeuroImage
Lukkarinen, Lasse; Tuisku, Jouni; Sun, Lihua; Helin, Semi; Karlsson, Henry K.; Venetjoki, Niina; Salomaa, Marja; Rautio, Päivi; Hirvonen, Jussi; Lauerma, Hannu; Tiihonen, Jari; Nummenmaa, Lauri
Blood biomarkers of neurodegeneration associate differently with amyloid deposition, medial temporal atrophy, and cerebrovascular changes in APOE ε4-enriched cognitively unimpaired elderly (2024)
- Alzheimer's Research and Therapy
Koivumäki, Mikko; Ekblad, Laura; Lantero-Rodriguez, Juan; Ashton, Nicholas J.; Karikari, Thomas K.; Helin, Semi; Parkkola, Riitta; Lötjönen, Jyrki; Zetterberg, Henrik; Blennow, Kaj; Rinne, Juha O.; Snellman, Anniina
Cognitively healthy APOE4/4 carriers show white matter impairment associated with serum NfL and amyloid-PET (2024)
- Neurobiology of Disease
Tato-Fernández, Claudia; Ekblad, Laura L.; Pietilä, Elina; Saunavaara, Virva; Helin, Semi; Parkkola, Riitta; Zetterberg, Henrik; Blennow, Kaj; Rinne, Juha O.; Snellman, Anniina
In-target production of [11C]CH4 from a nitrogen/hydrogen gas target as a function of beam current, irradiation time, and target temperature (2024)
- EJNMMI Radiopharmacy and Chemistry
Helin, Semi; Rajander, Johan; Aromaa, Jussi; Arponen, Eveliina; Helin, Jatta S.; Solin, Olof
Midlife insulin resistance, APOE genotype, and change in late-life brain beta-amyloid accumulation : A 5-year follow-up [11C]PIB-PET study (2024)
- Neurobiology of Disease
Pietilä, Elina; Snellman, Anniina; Tuisku, Jouni; Helin, Semi; Viitanen, Matti; Jula, Antti; Rinne, Juha O.; Ekblad, Laura L.
P2X 7-receptor binding in new-onset and secondary progressive MS – a [11C]SMW139 PET study (2024)
- EJNMMI Research
Lehto, Jussi; Aarnio, Richard; Tuisku, Jouni; Sucksdorff, Marcus; Koivumäki, Esa Mikko; Nylund, Marjo; Helin, Semi; Rajander, Johan; Danon, Jonathan; Gilchrist, Jayson; Kassiou, Michael; Oikonen, Vesa; Airas, Laura
[11C]carfentanil PET imaging for studying the peripheral opioid system in vivo: effect of photoperiod on mu-opioid receptor availability in brown adipose tissue (2023)
- European Journal of Nuclear Medicine and Molecular Imaging
Sun Lihua, Aarnio Richard, Herre Erika Atencio, Kärnä Salli, Palani Senthil, Virtanen Helena, Liljenbäck Heidi, Virta Jenni, Honkaniemi Aake, Oikonen Vesa, Han Chunlei, Laurila Sanna, Bucci Marco, Helin Semi, Yatkin Emrah, Nummenmaa Lauri, Nuutila Pirjo, Tang Jing, Roivainen Anne