Semi Helin - UTU Research Portal - UTU Research Portal

Semi Helin

- Senior Researcher,
Turku PET Centre (Independent units)

semhel@utu.fi

Publications

1 of 4

Aberrant type 2 dopamine and mu-opioid receptor availability in autism spectrum disorder (2025)
- European Journal of Nuclear Medicine and Molecular Imaging
Noppari, Tuomo; Tuisku, Jouni; Lukkarinen, Lasse; Tani, Pekka; Lindberg, Nina; Saure, Emma; Lauerma, Hannu; Tiihonen, Jari; Hirvonen, Jussi; Helin, Semi; Rajander, Johan; Salmi, Juha; Nummenmaa, Lauri
(A1 Refereed original research article in a scientific journal)
Anorexia nervosa is associated with higher brain mu-opioid receptor availability (2025)
- Molecular PsychiatryNeurobiology of Disease
Pak, Kyoungjune; Tuisku, Jouni; Karlsson, Henry K.; Hirvonen, Jussi; Rebelos, Eleni; Pekkarinen, Laura; Sun, Lihua; Latva-Rasku, Aino; Helin, Semi; Rajander, Johan; Karukivi, Max; Nuutila, Pirjo; Nummenmaa, Lauri
(A1 Refereed original research article in a scientific journal)
APOE4 carriership status influences [11C]PiB white matter retention in cognitively healthy older adultsCannabidiol modulates brain molecular alterations, gut microbiota dysbiosis and alcohol self-administration in a mouse model of fetal alcohol spectrum disorder (2025)
Tato-Fernández Claudia; Ekblad Laura L.; Bucci Marco; Tuisku Jouni; Parkkola Riitta; Helin Semi; Rinne Juha O.; Snellman Anniina
(A1 Refereed original research article in a scientific journal)
(2025)
- Biomedicine and Pharmacotherapy
Navarrete F.; Cabrera-Rubio R.; Gasparyan A.; Aarnio R.; López-Picón F.; Helin S.; Rajander J.; Collado M.C.; Manzanares J.
(A1 Refereed original research article in a scientific journal)
Lapsuusiän epilepsia saattaa altistaa myöhäisiän muistisairaudelle = Progression of amyloid accumulation in late adulthood among people with childhood-onset epilepsy (2025)
- Duodecim
Joutsa, Juho; Rinne, Juha O.; Niemi, Kalle J.; Karrasch, Mira; Parkkola, Riitta K.; Saunavaara, Jani; Helin, Semi; Hermann, Bruce B.; Sillanpää, Matti
(Other publication)
Neuroinflammation in Parkinson’s disease : A study with [11C]PBR28 PET and cerebrospinal fluid markers (2025)
- Parkinsonism and Related Disorders
Al-Abdulrasul, H.; Ajalin, R.; Tuisku, J.; Zetterberg, H.; Blennow, K.; Vahlberg, T.; Ekblad, L.; Helin, S.; Forsback, S.; Rinne, J.O.; Brück, A.
(A1 Refereed original research article in a scientific journal)
Obesity is associated with increased brain glucose uptake and activity but not neuroinflammation (TSPO availability) in monozygotic twin pairs discordant for BMI—Exercise training reverses increased brain activity (2025)
- Diabetes, Obesity and Metabolism
Hentilä, Jaakko; Tuisku, Jouni; Ojala, Ronja; Sun, Lihua; Lietzén, Martin S.; Virtanen, Heidi; Lautamäki, Riikka; Koskensalo, Kalle; Nummenmaa, Lauri; Löyttyniemi, Eliisa; Helin, Semi; Pietiläinen, Kirsi H.; Kaprio, Jaakko; Lahti, Leo; Malm, Tarja; Rinne, Juha O.; Hannukainen, Jarna C.
(A1 Refereed original research article in a scientific journal)
Progression of Amyloid Accumulation in Late Adulthood Among People With Childhood-Onset Epilepsy (2025)
- Neurology
Joutsa, Juho; Rinne, Juha O.; Niemi, Kalle J.; Karrasch, Mira; Parkkola, Riitta K.; Saunavaara, Jani; Helin, Semi P.; Hermann, Bruce P.; Sillanpää, Matti
(A1 Refereed original research article in a scientific journal)
Striatal cue-reactivity and neurotransmitter function in gambling disorder (2025)
- Journal of behavioral addictions
Bellmunt-Gil, Albert; Majuri, Joonas; Nummenmaa, Lauri; Helin, Semi; Forsback, Sarita; Rajander, Johan; Kaasinen, Valtteri; Joutsa, Juho
(A1 Refereed original research article in a scientific journal)
Aberrant type 2 dopamine receptor availability in violent offenders with psychopathy (2024)
- NeuroImage
Lukkarinen, Lasse; Tuisku, Jouni; Sun, Lihua; Helin, Semi; Karlsson, Henry K.; Venetjoki, Niina; Salomaa, Marja; Rautio, Päivi; Hirvonen, Jussi; Lauerma, Hannu; Tiihonen, Jari; Nummenmaa, Lauri

(A1 Refereed original research article in a scientific journal)
Blood biomarkers of neurodegeneration associate differently with amyloid deposition, medial temporal atrophy, and cerebrovascular changes in APOE ε4-enriched cognitively unimpaired elderly (2024)
- Alzheimer's Research and Therapy
Koivumäki Mikko, Ekblad Laura, Lantero-Rodriguez Juan, Ashton Nicholas J., Karikari Thomas K., Helin Semi, Parkkola Riitta, Lötjönen Jyrki, Zetterberg Henrik, Blennow Kaj, Rinne Juha O., Snellman Anniina
(A1 Refereed original research article in a scientific journal)
Cognitively healthy APOE4/4 carriers show white matter impairment associated with serum NfL and amyloid-PET (2024)
- Neurobiology of Disease
Tato-Fernández Claudia, Ekblad Laura L., Pietilä Elina, Saunavaara Virva, Helin Semi, Parkkola Riitta, Zetterberg Henrik, Blennow Kaj, Rinne Juha O., Snellman Anniina
(A1 Refereed original research article in a scientific journal)
In-target production of [11C]CH4 from a nitrogen/hydrogen gas target as a function of beam current, irradiation time, and target temperature (2024)
- EJNMMI Radiopharmacy and Chemistry
Helin Semi, Rajander Johan, Aromaa Jussi, Arponen Eveliina, Helin Jatta S, Solin Olof
(A1 Refereed original research article in a scientific journal)
2024
- Neurobiology of DiseaseEJNMMI Research
Pietilä Elina, Snellman Anniina, Tuisku Jouni, Helin Semi, Viitanen Matti, Jula Antti, Rinne Juha O., Ekblad Laura L.
(A1 Refereed original research article in a scientific journal)
P2X 7-receptor binding in new-onset and secondary progressive MS – a [11C]SMW139 PET study (2024)
Lehto, Jussi; Aarnio, Richard; Tuisku, Jouni; Sucksdorff, Marcus; Koivumäki, Esa Mikko; Nylund, Marjo; Helin, Semi; Rajander, Johan; Danon, Jonathan; Gilchrist, Jayson; Kassiou, Michael; Oikonen, Vesa; Airas, Laura
(A1 Refereed original research article in a scientific journal)
[11C]carfentanil PET imaging for studying the peripheral opioid system in vivo: effect of photoperiod on mu-opioid receptor availability in brown adipose tissue (2023)
- European Journal of Nuclear Medicine and Molecular ImagingAlzheimer's Research and Therapy
Sun Lihua, Aarnio Richard, Herre Erika Atencio, Kärnä Salli, Palani Senthil, Virtanen Helena, Liljenbäck Heidi, Virta Jenni, Honkaniemi Aake, Oikonen Vesa, Han Chunlei, Laurila Sanna, Bucci Marco, Helin Semi, Yatkin Emrah, Nummenmaa Lauri, Nuutila Pirjo, Tang Jing, Roivainen Anne
(A1 Refereed original research article in a scientific journal)
Adenosine A2A receptor availability in patients with early- and moderate-stage Parkinson’s disease (2023)
- Journal of NeurologyNeurobiology of Disease
Waggan Imran, Rissanen Eero, Tuisku Jouni, Joutsa Juho, Helin Semi, Parkkola Riitta, Rinne Juha O, Airas Laura
(A1 Refereed original research article in a scientific journal)
APOE ε4 gene dose effect on imaging and blood biomarkers of neuroinflammation and beta-amyloid in cognitively unimpaired elderly (2023)
Snellman Anniina, Ekblad Laura L., Tuisku Jouni, Koivumäki Mikko, Ashton Nicholas J., Lantero-Rodriguez Juan, Karikari Thomas K., Helin Semi, Bucci Marco, Löyttyniemi Eliisa, Parkkola Riitta, Karrasch Mira, Schöll Michael, Zetterberg Henrik, Blennow Kaj, Rinne Juha O.
(A1 Refereed original research article in a scientific journal)
Endogenous Opioid Release After Orgasm in Man: A Combined PET/Functional MRI Study (2023)
- Journal of Nuclear Medicine
Jern Patrick, Chen Jinglu, Tuisku Jouni, Saanijoki Tiina, Hirvonen Jussi, Lukkarinen Lasse, Manninen Sandra, Helin Semi, Putkinen Vesa, Nummenmaa Lauri
(A1 Refereed original research article in a scientific journal)
Head-to-head comparison of plasma p-tau181, p-tau231 and glial fibrillary acidic protein in clinically unimpaired elderly with three levels of APOE4-related risk for Alzheimer's disease (2023)
Snellman Anniina, Ekblad Laura L., Ashton Nicholas J., Karikari Thomas K., Lantero-Rodriguez Juan, Pietilä Elina, Koivumäki Mikko, Helin Semi, Karrasch Mira, Zetterberg Henrik, Blennow Kaj, Rinne Juha O.
(A1 Refereed original research article in a scientific journal)