Juha Mykkänen
 Dosentti (Adjunct professor)


juha.mykkanen@utu.fi

+358 29 450 4364

+358 50 406 3612

Kiinamyllynkatu 10

Turku

Office: B503


ORCID identifier: https://orcid.org/0000-0001-9898-2660(external)

The Cardiovascular Risk in Young Finns Study (YFS)(external)

Areas of expertise
cardiovascular and metabolic risk factors; metabolic disease; obesity; insulin resistance and type 2 diabetes; molecular genetics and genomics; metabolomics; transcriptomics; omics data analysis; statistics; type 1 diabetes; lysinuric protein intolerance; research project planning

Biography

EDUCATION AND DEGREES

2015 Adjunct professor (docent) of Molecular genetics, University of Turku (UTU)
2003 PhD, Medical genetics, UTU
1998 MSc, Genetics, UTU

CURRENT POSITION

Senior scientist, Research Centre of Applied and Preventive Cardiovascular Medicine, Medical Faculty, UTU

PAST POSITIONS
 
2009 – 2015    Senior scientist, Finnish Type 1 Diabetes Prediction and Prevention (DIPP) study, Department of Paediatrics and Adolescent Medicine, Turku University Hospital (TUH)
2005 – 2008    Academy of Finland Post-doctoral Researcher, Turku Centre for Biotechnology, UTU
2003 – 2008    Post-doctoral researcher, Turku Centre for Biotechnology, UTU
1998 – 2003    Post-graduate (PhD) training, Department of Medical Genetics, UTU
2000 – 2002    Part-time teacher, Department of Biology, UTU
1998 – 1999    Assistant (8 months), Department of Medical Genetics, UTU
1995 – 1997    Part-time research assistant, Department of Medical Genetics, UTU



Research

I have dedicated my whole career on human health related research. This started already during my pre-graduate stage when I was working in Adjunct professor Jaana Lähdetie's research group at the Department of Medical Genetics (UTU) studying sperm aneuploidy of testicular cancer patients treated with radiotherapy. After my M.Sc., I familiarized with molecular genetics of hereditary diseases in children. In my doctoral dissertation I studied the molecular genetics of hereditary lysinuric protein intolerance (LPI) disease under the guidance Prof. emeritus of Pertti Aula at the Medical Genetics department. During this time I familiarized with various methods of human genomics and the so-called Finnish disease heritage.

During my post-doc studies, I moved to the Turku Centre for Biotechnology (UTU) to study the development of Type 1 diabetes as part of the Finnish DIPP study. During this time, I studied of Type 1 diabetes, molecular immunology and various genomic biomedical research methods such genome-wide microarrays. During the post-doc period I was a post-doctoral researcher of the Academy of Finland, the subject of the Molecular Markers of Type 1 diabetes, where biospecimens collected from DIPP children were analysed using various microarray platforms (in-house cDNA, Affymetrix and Illumina) in order to find genes or gene networks that change early in the course of Type 1 diabetes development.

The third phase of my research career began in 2009 as a senior researcher at the DIPP Research Clinic (Department of Paediatrics and Adolescent Medicine, TUH) led by Prof. emeritus Olli Simell. My research interest was to dissect and identify factors that modulate the risk for Type 1 diabetes related autoimmunity.

The fourth phase of my research career started in March 2015 as a senior researcher in The Cardiovascular Risk in Young Finns Study (YFS) coordinated by Academy Professor Olli Raitakari at the Research Centre of Applied and Preventive Cardiovascular Medicine (UTU), where risk factors for cardiovascular and metabolic diseases are studied in great detail. The main aim of my current research is to dissect the complex interplay of human genome, transcriptome and metabolome with risk factors of cardiovascular and metabolic diseases, both in cross-sectional and longitudinal settings, to increase our understanding of pathophysiology of cardiovascular and metabolic diseases.



Teaching

Currently I supervise advanced studies or thesis in (bio)medicine.



Publications
  
Go to first page
  
Go to previous page
  
2 of 4
  
Go to next page
  
Go to last page
  

Last updated on 2023-12-07 at 12:34