Olli Pentikäinen
PhD
olli.pentikainen@utu.fi +358 40 521 6913 Kiinamyllynkatu 10 Turku |
Computer-Dependent Drug Discovery; Molecular Modeling; Protein structure-function relationship; Protein-protein interaction
Education:
MSc in (organic) chemistry 1995 (University of Joensuu, Finland)
PhD in Biochemistry 2003 (Åbo Akademi University)
Adjunct Professor in Biochemistry 2005- (University of Turku)
Positions:
2017- Professor of Medicinal Chemistry (University of Turku) 8/2017
2011- Senior Lecturer in Cell and Molecular Biology (University of Jyväskylä)
2015 Visiting Senior Scientist (University of Innsbruck, Austria)
2005-2006 Visiting Senior Scientist (University of Bristol, UK)
1999-2005 Manager in Molecular Discovery (FBD Ltd)
Our research focuses on discovery of efficient drug candidates and development of novel methods for that purpose. Especially our research on cancer drug targets that have been considered highly difficult, together with risk analysis of drug candidates, pave the road for safer drugs.
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- Efficient Virtual Screening Using Multiple Protein Conformations Described as Negative Images of the Ligand-Binding Site (2010)
- Journal of Chemical Information and Modeling
- Efficient Virtual Screening Using Multiple Protein Conformations Described as Negative Images of the Ligand-Binding Site (2010)
- Journal of Chemical Information and Modeling
- Exploring kainate receptor pharmacology using molecular dynamics simulations (2010)
- Neuropharmacology
- Exploring kainate receptor pharmacology using molecular dynamics simulations (2010)
- Neuropharmacology
- Ligand-binding Domain Determines Endoplasmic Reticulum Exit of AMPA Receptors (2010)
- Journal of Biological Chemistry
- Ligand-binding Domain Determines Endoplasmic Reticulum Exit of AMPA Receptors (2010)
- Journal of Biological Chemistry
- Mammary-derived growth inhibitor (MDGI) interacts with integrin alpha-subunits and suppresses integrin activity and invasion (2010)
- Oncogene
- Mammary-derived growth inhibitor (MDGI) interacts with integrin alpha-subunits and suppresses integrin activity and invasion (2010)
- Oncogene
- Pharmacological activity of C10-substituted analogs of the high-affinity kainate receptor agonist dysiherbaine (2010)
- Neuropharmacology
- Pharmacological activity of C10-substituted analogs of the high-affinity kainate receptor agonist dysiherbaine (2010)
- Neuropharmacology
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