Olli Pentikäinen
PhD
olli.pentikainen@utu.fi +358 40 521 6913 Kiinamyllynkatu 10 Turku |
Computer-Dependent Drug Discovery; Molecular Modeling; Protein structure-function relationship; Protein-protein interaction
Education:
MSc in (organic) chemistry 1995 (University of Joensuu, Finland)
PhD in Biochemistry 2003 (Åbo Akademi University)
Adjunct Professor in Biochemistry 2005- (University of Turku)
Positions:
2017- Professor of Medicinal Chemistry (University of Turku) 8/2017
2011- Senior Lecturer in Cell and Molecular Biology (University of Jyväskylä)
2015 Visiting Senior Scientist (University of Innsbruck, Austria)
2005-2006 Visiting Senior Scientist (University of Bristol, UK)
1999-2005 Manager in Molecular Discovery (FBD Ltd)
Our research focuses on discovery of efficient drug candidates and development of novel methods for that purpose. Especially our research on cancer drug targets that have been considered highly difficult, together with risk analysis of drug candidates, pave the road for safer drugs.
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- Fluorescent Small Molecule Probe to Modulate and Explore alpha 2 beta 1 Integrin FunctionCystic Fibrosis Transmembrane Conductance Regulator Interacts with Multiple Immunoglobulin Domains of Filamin A2011 Koivunen JT, Nissinen L, Kapyla J, Jokinen J, Pihlavisto M, Marjamaki A, Heino J, Huuskonen J, Pentikainen OT
- Full and Partial Agonism of Ionotropic Glutamate Receptors Indicated by Molecular Dynamics SimulationsCystic Fibrosis Transmembrane Conductance Regulator Interacts with Multiple Immunoglobulin Domains of Filamin A2011
- Journal of Chemical Information and ModelingJournal of Biological Chemistry
- Full and Partial Agonism of Ionotropic Glutamate Receptors Indicated by Molecular Dynamics Simulations (2011)
- Journal of Chemical Information and ModelingThrombosis and Haemostasis
- Novel Hydrazine Molecules as Tools To Understand the Flexibility of Vascular Adhesion Protein-1 Ligand-Binding Site: Toward More Selective Inhibitors (2011)
- Journal of Medicinal Chemistry
- (2011)
- Journal of Medicinal Chemistry
- Novel Hydrazine Molecules as Tools To Understand the Flexibility of Vascular Adhesion Protein-1 Ligand-Binding Site: Toward More Selective Inhibitors (2011)
- Journal of Medicinal Chemistry
- A small-molecule inhibitor of integrin alpha 2 beta 1 introduces a new strategy for antithrombotic therapy (2010)
- A small-molecule inhibitor of integrin alpha 2 beta 1 introduces a new strategy for antithrombotic therapy (2010)
- Thrombosis and Haemostasis
- (2010)
- Journal of Biological Chemistry
- (2010)
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