Markus Juonala
Professor
mataju@utu.fi +358 29 450 2754 +358 50 478 3572 |
Internal medicine; endocrinology; cardiovascular risk
Cardiovascular epidemiology, Young Finns Study, i3c consortium
Professor Markus Juonala (MD,
PhD, University of Turku) is a specialist in internal medicine and
endocrinology at the Turku University Hospital, Turku, Finland. Since 2001, he
has been conducting research on longitudinal studies examining the importance
of childhood risk factors on later cardiovascular health. His PhD work was
based primarily on the Cardiovascular Risk in Young Finns Study (University of
Turku, April 2005). Since 2008, he has had a major involvement in the
development of the International Childhood Cardiovascular Cohort (i3C)
Consortium that combines the efforts of the main longitudinal studies
worldwide. In June 2014, he was appointed as Professor of Internal Medicine at
the University of Turku. In 2014-2015 and 2018-2019 he has been working as the Dame Elisabeth Murdoch Fellow in Murdoch Childrens Research Institute
(MCRI).
His career
publications total is 270 (h-index 44) with published highlights including a
first-author paper in the New England Journal of Medicine, the first-ranked
general medicine journal, one paper in JAMA, the third-ranked general medicine
journal and 30 papers (11 as first/last author) published in either the number
one, two, or three ranked cardiovascular disease journals (17 in Circulation,
five in the Journal of the American College of Cardiology, eight in the
European Heart Journal).
Professor Juonala’s
principal research focus has been to provide novel information on the effects
of childhood risk factors on cardiovascular health in adulthood. Beginning from
the summer of 2008 he has led a research group within the Young Finns Study and
i3c consortium with special interest on cardiometabolic risk factors. The most
important findings of his research have provided information on childhood and
early adulthood risk factors for atherosclerosis, suggesting that childhood
risk factors, such as dyslipidaemia, elevated blood pressure and smoking,
predict early atherosclerosis and its progression independent of adult risk
factors levels. Concerning cardiometabolic risk factors, his group has been
able to show that overweight and metabolic syndrome diagnosed either in childhood or adulthood
is predictive of carotid atherosclerosis and its progression in adulthood.
However, at the time of obesity epidemic, the most important findings concern
the reversibility of cardiovascular risk. His work has demonstrated that although overweight and metabolic syndrome are predictive of early atherosclerosis, favourable changes
in lifestyle associated with weight maintenance or reduction improve
cardiovascular health.
Teaching responsibilities: 1) Internal medicine for medical students, 2) Internal medicine specialisation programme for MDs
Special interest areas: Acute internal medicine, endocrinology, lipidology
- Lasten karies ja ientulehdus lisäävät valtimotaudin riskiä aikusiällä (2019)
- Suuhygienisti
- Longitudinal analysis of risk of Non-Alcoholic Fatty Liver Disease (NAFLD) in adulthood (2019)
- Liver International
- Long-Term Burden of Increased Body Mass Index from Childhood on Adult Dyslipidemia: The i3C Consortium Study (2019)
- Journal of Clinical Medicine
- Metabolomics: population epidemiology and concordance in Australian children aged 11-12 years and their parents (2019)
- BMJ Open
- Neighbourhood socioeconomic circumstances, adiposity and cardiometabolic risk measures in children with severe obesity (2019)
- Obesity Research and Clinical Practice
- New evidence from plasma ceramides links apoE polymorphism to greater risk of coronary artery disease in Finnish adults (2019)
- Journal of Lipid Research
- Physical activity from childhood to adulthood and cognitive performance in midlife (2019)
- Medicine and Science in Sports and Exercise
- Predicting overweight and obesity in young adulthood from childhood body-mass index: comparison of cutoffs derived from longitudinal and cross-sectional data (2019)
- The Lancet Child & Adolescent Health
- Relation of Blood Pressure in Childhood to Self-Reported Hypertension in Adulthood: The International Childhood Cardiovascular Cohort Consortium (2019)
- Hypertension
- Sex and puberty-related differences in metabolomic profiles associated with adiposity measures in youth with obesity (2019)
- Metabolomics
- Socioeconomic position and intergenerational associations of ideal health behaviors (2019)
- European Journal of Preventive Cardiology
- Telomere Length and Vascular Phenotypes in a Population-Based Cohort of Children and Midlife Adults (2019)
- Journal of the American Heart Association
- The Australian Aboriginal Birth Cohort study: socio-economic status at birth and cardiovascular risk factors to 25 years of age (2019)
- Medical Journal of Australia
- The effect of apolipoprotein E polymorphism on serum metabolome - a population-based 10-year follow-up study (2019)
- Scientific Reports
- The great leap backward: changes in the jumping performance of Australian children aged 11−12-years between 1985 and 2015 (2019)
- Journal of Sports Sciences
- Time spent watching television impacts on body mass index in youth with obesity, but only in those with shortest sleep duration (2019)
- Journal of Paediatrics and Child Health
- Utility of Different Blood Pressure Measurement Components in Childhood to Predict Adult Carotid Intima-Media Thickness (2019)
- Hypertension
- Whole blood microRNA levels associate with glycemic status and correlate with target mRNAs in pathways important to type 2 diabetes (2019)
- Scientific Reports
- Youth and Long-Term Dietary Calcium Intake With Risk of Impaired Glucose Metabolism and Type 2 Diabetes in Adulthood (2019)
- Journal of Clinical Endocrinology and Metabolism
- Alirocumab and Cardiovascular Outcomes after Acute Coronary Syndrome (2018)
- New England Journal of Medicine