Markus Juonala
Professor
mataju@utu.fi +358 29 450 2754 +358 50 478 3572 |
Internal medicine; endocrinology; cardiovascular risk
Cardiovascular epidemiology, Young Finns Study, i3c consortium
Professor Markus Juonala (MD,
PhD, University of Turku) is a specialist in internal medicine and
endocrinology at the Turku University Hospital, Turku, Finland. Since 2001, he
has been conducting research on longitudinal studies examining the importance
of childhood risk factors on later cardiovascular health. His PhD work was
based primarily on the Cardiovascular Risk in Young Finns Study (University of
Turku, April 2005). Since 2008, he has had a major involvement in the
development of the International Childhood Cardiovascular Cohort (i3C)
Consortium that combines the efforts of the main longitudinal studies
worldwide. In June 2014, he was appointed as Professor of Internal Medicine at
the University of Turku. In 2014-2015 and 2018-2019 he has been working as the Dame Elisabeth Murdoch Fellow in Murdoch Childrens Research Institute
(MCRI).
His career
publications total is 270 (h-index 44) with published highlights including a
first-author paper in the New England Journal of Medicine, the first-ranked
general medicine journal, one paper in JAMA, the third-ranked general medicine
journal and 30 papers (11 as first/last author) published in either the number
one, two, or three ranked cardiovascular disease journals (17 in Circulation,
five in the Journal of the American College of Cardiology, eight in the
European Heart Journal).
Professor Juonala’s
principal research focus has been to provide novel information on the effects
of childhood risk factors on cardiovascular health in adulthood. Beginning from
the summer of 2008 he has led a research group within the Young Finns Study and
i3c consortium with special interest on cardiometabolic risk factors. The most
important findings of his research have provided information on childhood and
early adulthood risk factors for atherosclerosis, suggesting that childhood
risk factors, such as dyslipidaemia, elevated blood pressure and smoking,
predict early atherosclerosis and its progression independent of adult risk
factors levels. Concerning cardiometabolic risk factors, his group has been
able to show that overweight and metabolic syndrome diagnosed either in childhood or adulthood
is predictive of carotid atherosclerosis and its progression in adulthood.
However, at the time of obesity epidemic, the most important findings concern
the reversibility of cardiovascular risk. His work has demonstrated that although overweight and metabolic syndrome are predictive of early atherosclerosis, favourable changes
in lifestyle associated with weight maintenance or reduction improve
cardiovascular health.
Teaching responsibilities: 1) Internal medicine for medical students, 2) Internal medicine specialisation programme for MDs
Special interest areas: Acute internal medicine, endocrinology, lipidology
- A Clinical Tool to Relate Youth Risk Factors to Adult Cardiovascular Events and Type 2 Diabetes : The International Childhood Cardiovascular Cohort Consortium (2025)
- Journal of Pediatrics
- Association of neighbourhood and individual-level socioeconomic disadvantage in childhood and adulthood with cognitive function in mid-adulthood: Cardiovascular Risk in Young Finns Study (2025)
- American Journal of Epidemiology
- Blood pressure in childhood, young- and mid-adulthood: association with carotid plaque severity (2025)
- European Heart Journal
- Body Composition, Body Mass, and Cardiovascular Health in Mid-Childhood and Midlife: A Compositional Data Analysis (2025)
- Childhood obesity
- Cardiometabolic determinants of aortic and carotid intima-media thickness in adolescence (2025)
- Atherosclerosis
- Maternal Smoking Intensity During Pregnancy and Early Adolescent Cardiovascular Health (2025)
- Journal of the American Heart Association
- The association of childhood HDL cholesterol with atherosclerotic cardiovascular disease events in adults: findings from the International Childhood Cardiovascular Cohort Consortium (2025)
- European Journal of Preventive Cardiology
- Tracking and Transition Probability of Blood Pressure From Childhood to Midadulthood (2025)
- JAMA Pediatrics
- Association of Ideal Cardiovascular Health in Youth with Cancer Risk in Adulthood : Cardiovascular Risk in Young Finns Study (2024)
- Cancer Epidemiology, Biomarkers and Prevention
- Association of number of siblings with preclinical markers of cardiovascular disease The cardiovascular risk in Young Finns study (2024)
- International journal of cardiology : Cardiovascular risk and prevention
- Associations of Cumulative Adulthood, Childhood and Lifelong Insulin With Adulthood Retinal Microvasculature (2024)
- Journal of Clinical Endocrinology and Metabolism
- Cardiovascular Risk Factors in Childhood and Adulthood and Cardiovascular Disease in Middle Age (2024)
- JAMA Network Open
- Change in cognitive performance during seven-year follow-up in midlife is associated with sex, age, and education : The Cardiovascular Risk in Young Finns Study (2024)
- Journal of Neurology
- Childhood Non-HDL Cholesterol and LDL Cholesterol and Adult Atherosclerotic Cardiovascular Events (2024)
- Circulation
- Cognitive performance from childhood to old age and intergenerational correlations in the multigenerational Young Finns Study (2024)
- Journal of Neurology
- Correction to: Tracking of apolipoprotein B levels measured in childhood and adolescence: systematic review and meta-analysis (vol 183, pg 569, 2024) (2024)
- European Journal of Pediatrics
- Early intermittent hyperlipidaemia alters tissue macrophages to fuel atherosclerosis (2024)
- Nature
- Efficient Search Algorithms for Identifying Synergistic Associations in High-Dimensional Datasets (2024)
- Entropy
- Exposure to parental smoking and cardiac structure and function in adulthood: the Cardiovascular Risk in Young Finns Study (2024)
- Scandinavian Journal of Public Health
- Identification of gene networks jointly associated with depressive symptoms and cardiovascular health metrics using whole blood transcriptome in the Young Finns Study (2024)
- Frontiers in Psychiatry