Laura Lehtinen - UTU Research Portal

Laura Lehtinen

- Senior Researcher,
Institute of Biomedicine (Faculty of Medicine)

lauleh@utu.fi

+358 29 450 4614

+358 50 476 5793

Kiinamyllynkatu 10

Turku

Generation of three isogenic human induced pluripotent stem cell lines from normal neonate skin fibroblasts (2024)
- Stem Cell Research
Sandelin Sanne, Hakala Sofia, Lehtinen Laura, Närvä Elisa
Aggressive and recurrent ovarian cancers upregulate ephrinA5, a non-canonical effector of EphA2 signaling duality (2021)
- Scientific Reports
Jukonen Joonas, Moyano-Galceran Lidia, Höpfner Katrin, Pietilä Elina A, Lehtinen Laura, Huhtinen Kaisa, Gucciardo Erica, Hynninen Johanna, Hietanen Sakari, Grénman Seija, Ojala Päivi M, Carpén Olli, Lehti Kaisa
Co-evolution of matrisome and adaptive adhesion dynamics drives ovarian cancer chemoresistance (2021)
- Nature Communications
Pietilä Elina A., Gonzalez-Molina Jordi, Moyano-Galceran Lidia, Jamalzadeh Sanaz, Zhang Kaiyang, Lehtinen Laura, Turunen S. Pauliina, Martins Tomás A., Gultekin Okan, Lamminen Tarja, Kaipio Katja, Joneborg Ulrika, Hynninen Johanna, Hietanen Sakari, Grénman Seija, Lehtonen Rainer, Hautaniemi Sampsa, Carpén Olli, Carlson Joseph W., Lehti Kaisa
FHOD1 and FMNL1 formin proteins in intestinal gastric cancer: correlation with tumor-infiltrating T lymphocytes and molecular subtypes (2021)
- Gastric Cancer
Mansuri Naziha, Heuser Vanina D, Birkman Eva-Maria, Lintunen Minnamaija, Ålgars Annika, Sundström Jari, Ristamäki Raija, Carpén Olli, Lehtinen Laura
ALDH1A1-related stemness in high-grade serous ovarian cancer is a negative prognostic indicator but potentially targetable by EGFR/mTOR-PI3K/aurora kinase inhibitors (2020)
- Journal of Pathology
Katja Kaipio, Ping Chen, Pia Roering, Kaisa Huhtinen, Piia Mikkonen, Päivi Östling, Laura Lehtinen, Naziha Mansuri, Taina Korpela, Swapnil Potdar, Johanna Hynninen, Annika Auranen, Seija Grénman, Krister Wennerberg, Sampsa Hautaniemi, Olli Carpén
Association of tumor-infiltrating T lymphocytes with intestinal-type gastric cancer molecular subtypes and outcome (2020)
- Virchows Archiv
Mansuri Naziha, Birkman Eva-Maria, Heuser Vanina D., Lintunen Minnamaija, Ålgars Annika, Sundström Jari, Ristamäki Raija, Lehtinen Laura, Carpén Olli
Multiple formin proteins participate in glioblastoma migration (2020)
- BMC Cancer
Heuser VD, Kiviniemi A, Lehtinen L, Munthe S, Kristensen BW, Posti JP, Sipila JOT, Vuorinen V, Carpen O, Gardberg M
A Nanoparticle-Based Approach for the Detection of Extracellular Vesicles (2019)
- Scientific Reports
Md. Khirul Islam, Parvez Syed, Laura Lehtinen, Janne Leivo, Kamlesh Gidwani, Saara Wittfooth, Kim Pettersson, Urpo Lamminmäki
Prognostic and diagnostic value of REG4 serum and tissue expression in pancreatic ductal adenocarcinoma (2018)
- Tumor Biology
Kapo Saukkonen, Jaana Hagström, Harri Mustonen, Laura Lehtinen, Olli Carpen, Leif C Andersson, Hanna Seppänen, Caj Haglund
PLA2G7 associates with hormone receptor negativity in clinical breast cancer samples and regulates epithelial-mesenchymal transition in cultured breast cancer cells (2017)
- Journal of Pathology: Clinical Research
Lehtinen Laura, Vainio Paula, Wikman Harriet, Huhtala Heini, Mueller Volkmar, Kallioniemi Anne, Pantel Klaus, Kronqvist Pauliina, Kallioniemi Olli, Carpen Olli, Iljin Kristiina
Characterization of ascites and tumor-derived ovarian cancer stem-like cells (2016)
- Clinical Cancer Research
Kaipio K, Chen P, Huhtinen K, Mikkonen P, Ostling P, Mpindi JP, Lehtinen L, Roering P, Korpela T, Wennerberg K, Yadav B, Aittokallio T, Kulesskiy E, Hynninen J, Auranen A, Grenman S, Hautaniemi S, Carpen O
REG4 Is Highly Expressed in Mucinous Ovarian Cancer: A Potential Novel Serum Biomarker (2016)
- PLoS ONE
Laura Lehtinen, Pia Vesterkvist, Pia Roering, Taina Korpela, Liisa Hattara, Katja Kaipio, John-Patrick Mpindi, Johanna Hynninen, Annika Auranen, Ben Davidson, Caj Haglund, Kristiina Iljin, Seija Grenman, Harri Siitari, Olli Carpen
High-throughput RNAi screening for novel modulators of vimentin expression identifies MTHFD2 as a regulator of breast cancer cell migration and invasion (2013)
- Oncotarget
Lehtinen L, Ketola K, Makela R, Mpindi J, Viitala M, Kallioniemi O, Iljin K
15-Hydroxyprostaglandin dehydrogenase associates with poor prognosis in breast cancer, induces epithelial-mesenchymal transition, and promotes cell migration in cultured breast cancer cells. (2012)
- Journal of Pathology
Lehtinen L, Vainio P, Wikman H, Reemts J, Hilvo M, Issa R, Pollari S, Brandt B, Oresic M, Pantel K, Kallioniemi O, Iljin K
Identification of novel regulatory genes controlling epithelial to mesenchymal transition in cultured breast cancer cells (2012)
- Cancer Research
Lehtinen Laura, Mäkelä Rami, Kallioniemi Olli, Iljin Kristiina
Novel Theranostic Opportunities Offered by Characterization of Altered Membrane Lipid Metabolism in Breast Cancer Progression (2011)
- Cancer Research
Hilvo M, Denkert C, Lehtinen L, Muller B, Brockmoller S, Seppanen-Laakso T, Budczies J, Bucher E, Yetukuri L, Castillo S, Berg E, Nygren H, Sysi-Aho M, Griffin JL, Fiehn O, Loibl S, Richter-Ehrenstein C, Radke C, Hyotylainen T, Kallioniemi O, Iljin K, Oresic M
Phospholipase PLA2G7, associated with aggressive prostate cancer, promotes prostate cancer cell migration and invasion and is inhibited by statins (2011)
- Oncotarget
Vainio Paula, Lehtinen Laura, Mirtti Tuomas, Hilvo Mika, Seppänen-Laakso Tuulikki, Virtanen Johannes, Sankila Anna, Nordling Stig, Lundin Johan, Rannikko Antti, Orešic Matej, Kallioniemi Olli, Iljin Kristiina
Integrative functional genomics analysis of sustained polyploidy phenotypes in breast cancer cells identifies an oncogenic profile for GINS2. (2010)
- Neoplasia
Rantala JK, Edgren H, Lehtinen L, Wolf M, Kleivi K, Vollan HK, Aaltola AR, Laasola P, Kilpinen S, Saviranta P, Iljin K, Kallioniemi O