Laura Lehtinen - UTU Research Portal

Laura Lehtinen

- Senior Researcher,
Institute of Biomedicine (Faculty of Medicine)

lauleh@utu.fi

+358 29 450 4614

+358 50 476 5793

Kiinamyllynkatu 10

Turku

ORCID identifier: https://orcid.org/0000-0001-7383-0353

Publications

1 of 2

Molecular Characterization of Extracellular Vesicles From Human B Cell Lymphomas: Methodological Comparison to Vesicles From Patient Serum (2026)
- Journal of Extracellular Biology
Badal, Md Nasir Uddin; Koivula, Tiia; Islam, Md Khirul; Lehtinen, Laura; Kauko, Otto; Leivo, Janne; Heinonen, Ilkka; Hämälistö, Saara
(A1 Refereed original research article in a scientific journal)
Generation of three isogenic human induced pluripotent stem cell lines from normal neonate skin fibroblasts (2024)
- Stem Cell Research
Sandelin, Sanne; Hakala, Sofia; Lehtinen, Laura; Närvä, Elisa
(A1 Refereed original research article in a scientific journal)
Respiratory complex I regulates dendritic cell maturation in explant model of human tumor immune microenvironment (2024)
- Journal for Immunotherapy of Cancer
Turpin Rita; Liu Ruixian; Munne Pauliina M; Peura Aino; Rannikko Jenna H; Philips Gino; Boeckx Bram; Salmelin Natasha; Hurskainen Elina; Suleymanova Ilida; Aung July; Vuorinen Elisa M; Lehtinen Laura; Mutka Minna; Kovanen Panu E; Niinikoski Laura; Meretoja Tuomo J; Mattson Johanna; Mustjoki Satu; Saavalainen Päivi; Goga Andrei; Lambrechts Diether; Pouwels Jeroen; Hollmén Maija; Klefström Juha
(A1 Refereed original research article in a scientific journal)
Aggressive and recurrent ovarian cancers upregulate ephrinA5, a non-canonical effector of EphA2 signaling duality (2021)
- Scientific Reports
Jukonen Joonas, Moyano-Galceran Lidia, Höpfner Katrin, Pietilä Elina A, Lehtinen Laura, Huhtinen Kaisa, Gucciardo Erica, Hynninen Johanna, Hietanen Sakari, Grénman Seija, Ojala Päivi M, Carpén Olli, Lehti Kaisa
(A1 Refereed original research article in a scientific journal)
Co-evolution of matrisome and adaptive adhesion dynamics drives ovarian cancer chemoresistance (2021)
- Nature Communications
Pietilä Elina A., Gonzalez-Molina Jordi, Moyano-Galceran Lidia, Jamalzadeh Sanaz, Zhang Kaiyang, Lehtinen Laura, Turunen S. Pauliina, Martins Tomás A., Gultekin Okan, Lamminen Tarja, Kaipio Katja, Joneborg Ulrika, Hynninen Johanna, Hietanen Sakari, Grénman Seija, Lehtonen Rainer, Hautaniemi Sampsa, Carpén Olli, Carlson Joseph W., Lehti Kaisa
(A1 Refereed original research article in a scientific journal)
FHOD1 and FMNL1 formin proteins in intestinal gastric cancer: correlation with tumor-infiltrating T lymphocytes and molecular subtypes (2021)
- Gastric Cancer
Mansuri Naziha, Heuser Vanina D, Birkman Eva-Maria, Lintunen Minnamaija, Ålgars Annika, Sundström Jari, Ristamäki Raija, Carpén Olli, Lehtinen Laura
(A1 Refereed original research article in a scientific journal)
ALDH1A1-related stemness in high-grade serous ovarian cancer is a negative prognostic indicator but potentially targetable by EGFR/mTOR-PI3K/aurora kinase inhibitors (2020)
- Journal of Pathology
Katja Kaipio, Ping Chen, Pia Roering, Kaisa Huhtinen, Piia Mikkonen, Päivi Östling, Laura Lehtinen, Naziha Mansuri, Taina Korpela, Swapnil Potdar, Johanna Hynninen, Annika Auranen, Seija Grénman, Krister Wennerberg, Sampsa Hautaniemi, Olli Carpén
(A1 Refereed original research article in a scientific journal)
Association of tumor-infiltrating T lymphocytes with intestinal-type gastric cancer molecular subtypes and outcome (2020)
- Virchows Archiv
Mansuri Naziha, Birkman Eva-Maria, Heuser Vanina D., Lintunen Minnamaija, Ålgars Annika, Sundström Jari, Ristamäki Raija, Lehtinen Laura, Carpén Olli
(A1 Refereed original research article in a scientific journal)
Multiple formin proteins participate in glioblastoma migration (2020)
- BMC Cancer
Heuser VD, Kiviniemi A, Lehtinen L, Munthe S, Kristensen BW, Posti JP, Sipila JOT, Vuorinen V, Carpen O, Gardberg M
(A1 Refereed original research article in a scientific journal)
A Nanoparticle-Based Approach for the Detection of Extracellular Vesicles (2019)
- Scientific Reports
Md. Khirul Islam, Parvez Syed, Laura Lehtinen, Janne Leivo, Kamlesh Gidwani, Saara Wittfooth, Kim Pettersson, Urpo Lamminmäki
(A1 Refereed original research article in a scientific journal)
Prognostic and diagnostic value of REG4 serum and tissue expression in pancreatic ductal adenocarcinoma (2018)
- Tumor Biology
Kapo Saukkonen, Jaana Hagström, Harri Mustonen, Laura Lehtinen, Olli Carpen, Leif C Andersson, Hanna Seppänen, Caj Haglund
(A1 Refereed original research article in a scientific journal)
PLA2G7 associates with hormone receptor negativity in clinical breast cancer samples and regulates epithelial-mesenchymal transition in cultured breast cancer cells (2017)
- Journal of Pathology: Clinical Research
Lehtinen Laura, Vainio Paula, Wikman Harriet, Huhtala Heini, Mueller Volkmar, Kallioniemi Anne, Pantel Klaus, Kronqvist Pauliina, Kallioniemi Olli, Carpen Olli, Iljin Kristiina
(A1 Refereed original research article in a scientific journal)
Characterization of ascites and tumor-derived ovarian cancer stem-like cells (2016)
- Clinical Cancer Research
Kaipio K, Chen P, Huhtinen K, Mikkonen P, Ostling P, Mpindi JP, Lehtinen L, Roering P, Korpela T, Wennerberg K, Yadav B, Aittokallio T, Kulesskiy E, Hynninen J, Auranen A, Grenman S, Hautaniemi S, Carpen O
(Other publication)
REG4 Is Highly Expressed in Mucinous Ovarian Cancer: A Potential Novel Serum Biomarker (2016)
- PLoS ONE
Laura Lehtinen, Pia Vesterkvist, Pia Roering, Taina Korpela, Liisa Hattara, Katja Kaipio, John-Patrick Mpindi, Johanna Hynninen, Annika Auranen, Ben Davidson, Caj Haglund, Kristiina Iljin, Seija Grenman, Harri Siitari, Olli Carpen
(A1 Refereed original research article in a scientific journal)
FHOD1, a Formin Upregulated in Epithelial-Mesenchymal Transition, Participates in Cancer Cell Migration and Invasion (2013)
- PLoS ONE
Gardberg M, Kaipio K, Lehtinen L, Mikkonen P, Heuser VD, Talvinen K, Iljin K, Kampf C, Uhlen M, Grenman R, Koivisto M, Carpen O
(A1 Refereed original research article in a scientific journal)
High-throughput RNAi screening for novel modulators of vimentin expression identifies MTHFD2 as a regulator of breast cancer cell migration and invasion (2013)
- Oncotarget
Lehtinen L, Ketola K, Makela R, Mpindi J, Viitala M, Kallioniemi O, Iljin K
(A1 Refereed original research article in a scientific journal)
15-Hydroxyprostaglandin dehydrogenase associates with poor prognosis in breast cancer, induces epithelial-mesenchymal transition, and promotes cell migration in cultured breast cancer cells. (2012)
- Journal of Pathology
Lehtinen L, Vainio P, Wikman H, Reemts J, Hilvo M, Issa R, Pollari S, Brandt B, Oresic M, Pantel K, Kallioniemi O, Iljin K
(A1 Refereed original research article in a scientific journal)
Identification of novel regulatory genes controlling epithelial to mesenchymal transition in cultured breast cancer cells (2012)
- Cancer Research
Lehtinen Laura, Mäkelä Rami, Kallioniemi Olli, Iljin Kristiina
(Other publication)
Novel Theranostic Opportunities Offered by Characterization of Altered Membrane Lipid Metabolism in Breast Cancer Progression (2011)
- Cancer Research
Hilvo M, Denkert C, Lehtinen L, Muller B, Brockmoller S, Seppanen-Laakso T, Budczies J, Bucher E, Yetukuri L, Castillo S, Berg E, Nygren H, Sysi-Aho M, Griffin JL, Fiehn O, Loibl S, Richter-Ehrenstein C, Radke C, Hyotylainen T, Kallioniemi O, Iljin K, Oresic M
(A1 Refereed original research article in a scientific journal)
Phospholipase PLA2G7, associated with aggressive prostate cancer, promotes prostate cancer cell migration and invasion and is inhibited by statins (2011)
- Oncotarget
Vainio Paula, Lehtinen Laura, Mirtti Tuomas, Hilvo Mika, Seppänen-Laakso Tuulikki, Virtanen Johannes, Sankila Anna, Nordling Stig, Lundin Johan, Rannikko Antti, Orešic Matej, Kallioniemi Olli, Iljin Kristiina
(A1 Refereed original research article in a scientific journal)