MD/PhD Olli Raitakari - UTU Research Portal

Olli Raitakari
MD/PhD

- Professor,
Cardiovascular Medicine (CAPC) (Centre for Population Health Research (POP Centre))
- ,
InFLAMES Flagship (Faculty of Medicine)

olli.raitakari@utu.fi

+358 29 450 2304

Kiinamyllynkatu 10

Turku

ORCID identifier: https://orcid.org/0000-0001-9365-3702

10_representative_publications.pdf

Areas of expertise

cardiovascular and metabolic diseases; risk factors; vascular epidemiology; genetic epidemiology; epidemiology; dietary intervention; cohort studies; follow-up studies

Biography

EDUCATION AND DEGREES

2001   Docent in Clinical Physiology
1997-1999  Postdoc training, Royal Prince Alfred Hospital, Sydney, Australia
1997   Docent in Epidemiology
1996   Specialist in Clinical Physiology
1995   Doctorate, PhD
1989   Licentiate in Medicine, MD

CURRENT POSITIONS

2017- Professor in Cardiovascular Medicine, Director of the Research Centre of Applied and
Preventive Cardiovascular Medicine, University of Turku, Finland

PAST POSITIONS

2012-2016 Academy Professor, University of Turku

2007-2016 Professor in Cardiovascular Medicine (part time), University of Turku

2007-2008 Senior Scientist Grant, Academy of Finland

2004-2016 Chief Physician, Department of Clinical Physiology and Nuclear Medicine, Turku
University Hospital (leave of absence 2012-2016)

2002-2004 Consultant in Clinical Physiology and Nuclear Medicine, Turku University Hospital

2002 (1 mo) Head of Nuclear Medicine Department, Turku University Hospital

2000-2003 (3 mo) Head of Clinical Physiology Department, Turku University Hospital

2000-2005 Senior Fellow Post, Academy of Finland

1998-2000 Postdoctoral Research Post, Academy of Finland

1996-1997 Consultant in Clinical Physiology, Turku University Hospital

1991-1996 Positions as Resident in Clinical Chemistry, Nuclear Medicine, and Clinical
Physiology, Turku University Hospital

1988-1990 Positions as General Practioner and Resident in Internal Medicine or Surgery

Research

Evidence suggest that many non-communicable disease outcomes have roots in childhood and may even stem of adverse ancestral exposures. Improved knowledge how various ancestral and early-life exposures lead to adult disease outcomes is essential in developing better preventive practices and policies that lead to improved public health. My mission has been to contribute to this knowledge-base by working in epidemiologic cohort studies with follow-up from childhood to adulthood. I am the Principal Investigator of the Cardiovascular Risk in Young Finns Study (YFS), the largest study in Europe with a follow-up of cardiovascular risk factors from childhood to adulthood. I am also the Director of the STRIP Study, which is a leading long-term pediatric dietary intervention study testing the hypothesis that modifying the fat quality diet will have beneficial effects on cardiovascular risk early in life. During the past years, I have organized several field studies in these cohorts, and introduced novel technologies, such as imaging studies, genetic epidemiology methods and metabolomics approaches in these unique population resources. Our research has contributed to the understanding of pre-clinical development of atherosclerosis in children and young adults, including the effects of diet, life-style, metabolic risk factors, psychological traits and psychosocial factors, inflammation, hormones and genetic markers. For example, by applying non-invasive imaging methods in the Young Finns Study, we have demonstrated that exposure to adverse lipids, elevated blood pressure and obesity in childhood is related to atherosclerosis development in adulthood (JAMA 2003). Subsequent work stemmed from this initial observation has led to numerous original publications that have shown in detail how exposure to a large range of aetiogenic factors early in life contribute to the development of cardio-metabolic outcomes in adulthood. For example, by pooling international i3C Consortium data, we have demonstrated that overweight or obese children who became non-obese by adulthood had similar risks of many cardio-metabolic adult outcomes as individuals who were never obese (NEJM 2011). Thus, the results of our studies have clearly demonstrated that individual’s exposure to various stressors in early life is contributing to his/her adult phenotype and disease risk. The results have had significant impact on preventive practices. As a concrete demonstration of the international recognition and impact of my team’s work, many of our studies are widely cited in all updated paediatric guidelines on cardiovascular prevention both in Europe and in US.

Publications

33 of 51

The Combined Effect of Common Genetic Risk Variants on Circulating Lipoproteins Is Evident in Childhood: A Longitudinal Analysis of the Cardiovascular Risk in Young Finns Study (2016)
- PLoS ONE
Marie-jeanne Buscot, Costan G. Magnussen, Markus Juonala, Niina Pitkänen, Terho Lehtimäki, Jorma S.A. Viikari, Mika Kähönen, Nina Hutri-Kähönen, Nicholas J. Schork, Olli T. Raitakari, Russell J. Thomson
(A1 Refereed original research article in a scientific journal)
The effect of weight on labor market outcomes: an application of genetic instrumental variables (2016) John Cawley, Jutta Viinikainen, Terho Lehtimäki, Suvi Rovio, Ilkka Seppälä, Jaakko Pehkonen, Olli Raitakari
(D4 Published development or research report or study )
The serum copper/zinc ratio in childhood and educational attainment: a population-based study (2016)
- Journal of Public Health
Böckerman P, Bryson A, Viinikainen J, Viikari J, Lehtimäki T, Vuori E, Keltikangas-Järvinen L, Raitakari O, Pehkonen J
(A1 Refereed original research article in a scientific journal)
The trajectory of the blood DNA methylome ageing rate is largely set before adulthood: evidence from two longitudinal studies (2016)
- AGE
L. Kananen, S. Marttila, T. Nevalainen, L. Kummola, I. Junttila, N. Mononen, M. Kähönen, O. T. Raitakari, A. Hervonen, M. Jylhä, T. Lehtimäki, M. Hurme, J. Jylhävä
(A1 Refereed original research article in a scientific journal)
Trajectories of Physical Activity Predict the Onset of Depressive Symptoms but Not Their Progression: A Prospective Cohort Study (2016)
- Journal of Sports Medicine
Kaseva K, Rosenström T, Hintsa T, Pulkki-Råback L, Tammelin T, Lipsanen J, Yang X, Hintsanen M, Hakulinen C, Pahkala K, Hirvensalo M, Hutri-Kähönen N, Raitakari OT, Keltikangas-Järvinen L
(A1 Refereed original research article in a scientific journal)
Trends in adult body-mass index in 200 countries from 1975 to 2014: a pooled analysis of 1698 population-based measurement studies with 19·2 million participants (2016)
- Lancet
Di Cesare M, Bentham J, Stevens GA, Zhou B, Danaei G, Lu Y, Bixby H, Cowan MJ, Riley LM, Hajifathalian K, Fortunato L, Taddei C, Bennett JE, Ikeda N, Khang YH, Kyobutungi C, Laxmaiah A, Li Y, Lin HH, Miranda JJ, Mostafa A, Turley ML, Paciorek CJ, Gunter M, Ezzati M, Abdeen ZA, Abdul Hamid Z, Abu-Rmeileh NM, Acosta-Cazares B, Adams R, Aekplakorn W, Aguilar-Salinas CA, Ahmadvand A, Ahrens W, Ali MM, Alkerwi A, Alvarez-Pedrerol M, Aly E, Amouyel P, Amuzu A, Andersen LB, Anderssen SA, Andrade DS, Anjana RM, Aounallah-Skhiri H, Ariansen I, Aris T, Arlappa N, Arveiler D, Assah FK, Avdicová M, Azizi F, Beheshti S, Babu BV, Balakrishna N, Bandosz P, Banegas JR, Barbagallo CM, Barceló A, Barkat A, Barros MV, Bata I, Batieha AM, Batista RL, Baur LA, Beaglehole R, Ben Romdhane H, Benet M, Bernabe-Ortiz A, Bernotiene G, Bettiol H, Bhagyalaxmi A, Bharadwaj S, Bhargava SK, Bhatti Z, Bhutta ZA, Bi H, Bi Y, Bjerregaard P, Bjertness E, Bjertness MB, Björkelund C, Blake M, Blokstra A, Bo S, Bobak M, Boddy LM, Boehm BO, Boeing H, Boissonnet CP, Bongard V, Bovet P, Braeckman L, Bragt MC, Brajkovich I, Branca F, Breckenkamp J, Brenner H, Brewster LM, Brian GR, Bruno G, Bueno-de-Mesquita HB, Bugge A, Burns C, Cabrera de León A, Cacciottolo J, Cama T, Cameron C, Camolas J, Can G, Cândido AP, Capuano V, Cardoso VC, Carvalho MJ, Casanueva F, Casas JP, Caserta CA, Castetbon K, Chamukuttan S, Chan AW, Chan Q, Chaturvedi HK, Chaturvedi N, Chen CJ, Chen F, Chen H, Chen S, Chen Z, Cheng CY, Chetrit A, Chiolero A, Chiou ST, Chirita-Emandi A, Cho Y, Christensen K, Chudek J, Cifkova R, Claessens F, Clays E, Concin H, Cooper C, Cooper R, Coppinger TC, Costanzo S, Cottel D, Cowell C, Craig CL, Crujeiras AB, D'Arrigo G, d'Orsi E, Dallongeville J, Damasceno A, Damsgaard CT, Danaei G, Dankner R, Dauchet L, De Backer G, De Bacquer D, de Gaetano G, De Henauw S, De Smedt D, Deepa M, Deev AD, Dehghan A, Delisle H, Delpeuch F, Dhana K, Di Castelnuovo AF, Dias-da-Costa JS, Diaz A, Djalalinia S, Do HT, Dobson AJ, Donfrancesco C, Döring A, Doua K, Drygas W, Egbagbe EE, Eggertsen R, Ekelund U, El Ati J, Elliott P, Engle-Stone R, Erasmus RT, Erem C, Eriksen L, Escobedo-de la Peña J, Evans A, Faeh D, Fall CH, Farzadfar F, Felix-Redondo FJ, Ferguson TS, Fernández-Bergés D, Ferrante D, Ferrari M, Ferreccio C, Ferrieres J, Finn JD, Fischer K, Flores EM, Föger B, Foo LH, Forslund AS, Fortmann SP, Fouad HM, Francis DK, Franco Mdo C, Franco OH, Frontera G, Fuchs FD, Fuchs SC, Fujita Y, Furusawa T, Gaciong Z, Gafencu M, Gareta D, Garnett SP, Gaspoz JM, Gasull M, Gates L, Geleijnse JM, Ghasemian A, Giampaoli S, Gianfagna F, Giovannelli J, Giwercman A, Goldsmith RA, Gonzalez Gross M, González Rivas JP, Gorbea MB, Gottrand F, Graff -Iversen S, Grafnetter D, Grajda A, Grammatikopoulou MG, Gregor RD, Grodzicki T, Grøntved A, Gruden G, Grujic V, Gu D, Guan OP, Gudnason V, Guerrero R, Guessous I, Guimaraes AL, Gulliford MC, Gunnlaugsdottir J, Gunter M, Guo XH, Guo Y, Gupta PC, Gureje O, Gurzkowska B, Gutierrez L, Gutzwiller F, Halkjær J, Hardy R, Hari Kumar R, Hayes AJ, He J, Hendriks ME, Hernandez Cadena L, Heshmat R, Hihtaniemi IT, Ho SY, Ho SC, Hobbs M, Hofman A, Hormiga CM, Horta BL, Houti L, Htay TT, Htet AS, Htike MM, Hu Y, Hussieni AS, Huu CN, Huybrechts I, Hwalla N, Iacoviello L, Iannone AG, Ibrahim MM, Ikeda N, Ikram MA, Irazola VE, Islam M, Iwasaki M, Jackson RT, Jacobs JM, Jafar T, Jamil KM, Jamrozik K, Jasienska G, Jiang CQ, Joffres M, Johansson M, Jonas JB, Jørgensen T, Joshi P, Juolevi A, Jurak G, Jureša V, Kaaks R, Kafatos A, Kalter-Leibovici O, Kapantais E, Kasaeian A, Katz J, Kaur P, Kavousi M, Keil U, Keinan Boker L, Kelishadi R, Kemper H, Kengne AP, Kersting M, Key T, Khader YS, Khalili D, Khang YH, Khaw KT, Khouw IM, Kiechl S, Killewo J, Kim J, Kiyohara Y, Klimont J, Kolle E, Kolsteren P, Korrovits P, Koskinen S, Kouda K, Koziel S, Kratzer W, Krokstad S, Kromhout D, Kruger HS, Kula K, Kulaga Z, Kumar RK, Kusuma YS, Kuulasmaa K, Kyobutungi C, Laamiri FZ, Laatikainen T, Lachat C, Laid Y, Lam TH, Landrove O, Lanska V, Lappas G, Laugsand LE, Laxmaiah A, Le Nguyen Bao K, Le TD, Leclercq C, Lee J, Lee J, Lehtimäki T, Lekhraj R, León-Muñoz LM, Li Y, Lim WY, Lima-Costa MF, Lin HH, Lin X, Linneberg A, Lissner L, Litwin M, Liu J, Lorbeer R, Lotufo PA, Lozano JE, Luksiene D, Lundqvist A, Lunet N, Lytsy P, Ma G, Machi S, Maggi S, Magliano DJ, Makdisse M, Malekzadeh R, Malhotra R, Mallikharjuna Rao K, Manios Y, Mann J, Manzato E, Margozzini P, Markey O, Marques-Vidal P, Marrugat J, Martin-Prevel Y, Martorell R, Masoodi SR, Matsha TE, Mazur A, Mbanya JC, McFarlane SR, McGarvey ST, McKee M, McLachlan S, McLean RM, McNulty BA, Md Yusof S, Mediene-Benchekor S, Meirhaeghe A, Meisinger C, Mendes LL, Menezes AM, Mensink GB, Meshram II, Metspalu A, Mi J, Michaelsen KF, Mikkel K, Miller JC, Miquel JF, Miranda JJ, Mišigoj-Duraković M, Mohamed MK, Mohammad K, Mohammadifard N, Mohan V, Mohd Yusoff MF, Molbo D, Møller NC, Molnár D, Mondo CK, Monterrubio EA, Monyeki KD, Moreira LB, Morejon A, Moreno LA, Morgan K, Mortensen EL, Moschonis G, Mossakowska M, Mostafa A, Mota J, Motlagh ME, Motta J, Mu TT, Muiesan ML, Müller-Nurasyid M, Murphy N, Mursu J, Murtagh EM, Musa KI, Musil V, Nagel G, Nakamura H, Námešná J, Nang EE, Nangia VB, Nankap M, Narake S, Navarrete-Muñoz EM, Nenko I, Neovius M, Nervi F, Neuhauser HK, Nguyen ND, Nguyen QN, Nieto-Martínez RE, Ning G, Ninomiya T, Nishtar S, Noale M, Norat T, Noto D, Nsour MA, O'Reilly D, Ochoa-Avilés AM, Oh K, Olayan IH, Olinto MT, Oltarzewski M, Omar M, Onat A, Ordunez P, Ortiz AP, Osler M, Osmond C, Ostojic SM, Otero JA, Overvad K, Paccaud FM, Padez C, Pajak A, Palli D, Palloni A, Palmieri L, Panda-Jonas S, Panza F, Parnell WR, Parsaeian M, Pednekar MS, Peeters PH, Peixoto SV, Pereira AC, Pérez CM, Peters A, Peykari N, Pham ST, Pigeot I, Pikhart H, Pilav A, Pilotto L, Pistelli F, Pitakaka F, Piwonska A, Piwonski J, Plans-Rubió P, Poh BK, Porta M, Portegies ML, Poulimeneas D, Pradeepa R, Prashant M, Price JF, Puiu M, Punab M, Qasrawi RF, Qorbani M, Quoc Bao T, Radic I, Radisauskas R, Rahman M, Raitakari O, Raj M, Ramachandra Rao S, Ramachandran A, Ramke J, Ramos R, Rampal S, Rasmussen F, Redon J, Reganit PF, Ribeiro R, Riboli E, Rigo F, Rinke de Wit TF, Ritti-Dias RM, Rivera JA, Robinson SM, Robitaille C, Rodríguez-Artalejo F, Rodriguez-Perez Mdel C, Rodríguez-Villamizar LA, Rojas-Martinez R, Rojroongwasinkul N, Romaguera D, Ronkainen K, Rosengren A, Rouse I, Rubinstein A, Rühli FJ, Rui O, Ruiz-Betancourt BS, Russo Horimoto AR, Rutkowski M, Sabanayagam C, Sachdev HS, Saidi O, Salanave B, Salazar Martinez E, Salomaa V, Salonen JT, Salvetti M, Sánchez-Abanto J, Sandjaja, Sans S, Santos DA, Santos O, dos Santos RN, Santos R, Sardinha LB, Sarrafzadegan N, Saum KU, Savva SC, Scazufca M, Schaffrath Rosario A, Schargrodsky H, Schienkiewitz A, Schmidt IM, Schneider IJ, Schultsz C, Schutte AE, Sein AA, Senbanjo IO, Sepanlou SG, Shalnova SA, Shaw JE, Shibuya K, Shin Y, Shiri R, Siantar R, Sibai AM, Silva AM, Silva DA, Simon M, Simons J, Simons LA, Sjostrom M, Slowikowska-Hilczer J, Slusarczyk P, Smeeth L, Smith MC, Snijder MB, So HK, Sobngwi E, Söderberg S, Soekatri MY, Solfrizzi V, Sonestedt E, Sørensen TI, Sorić M, Sossa Jérome C, Soumare A, Staessen JA, Starc G, Stathopoulou MG, Staub K, Stavreski B, Steene-Johannessen J, Stehle P, Stein AD, Stergiou GS, Stessman J, Stieber J, Stöckl D, Stocks T, Stokwiszewski J, Stratton G, Strufaldi MW, Sun CA, Sundström J, Sung YT, Sunyer J, Suriyawongpaisal P, Swinburn B, Sy RG, Szponar L, Tai ES, Tammesoo ML, Tamosiunas A, Tang L, Tang X, Tanser F, Tao Y, Tarawneh M, Tarp J, Tarqui-Mamani CB, Taylor A, Tchibindat F, Thijs L, Thuesen BH, Tjonneland A, Tolonen HK, Tolstrup JS, Topbas M, Topór-Madry R, Torrent M, Traissac P, Trichopoulou A, Trichopoulos D, Trinh OT, Trivedi A, Tshepo L, Tulloch-Reid MK, Tuomainen TP, Tuomilehto J, Turley ML, Tynelius P, Tzotzas T, Tzourio C, Ueda P, Ukoli FA, Ulmer H, Unal B, Valdivia G, Vale S, Valvi D, van der Schouw YT, Van Herck K, Van Minh H, van Valkengoed IG, Vanderschueren D, Vanuzzo D, Vatten L, Vega T, Velasquez-Melendez G, Veronesi G, Verschuren WM, Viegi G, Viet L, Viikari-Juntura E, Vineis P, Vioque J, Virtanen JK, Visvikis-Siest S, Viswanathan B, Vollenweider P, Voutilainen S, Vrijheid M, Wade AN, Wagner A, Walton J, Wan N, Wan M, Wang MD, Wang Q, Wang YX, Wannamethee SG, Wareham N, Weerasekera D, Whincup PH, Widhalm K, Widyahening I, Wiecek A, Wilks RJ, Willeit J, Wojtyniak B, Wong JE, Wong TY, Woo J, Woodward M, Wu FC, Wu J, Wu SL, Xu H, Xu L, Yamborisut U, Yan W, Yang X, Yardim N, Ye X, Yiallouros PK, Yoshihara A, You QS, Younger-Coleman NO, Yusoff AF, Zainuddin A, Zambon S, Zdrojewski T, Zeng Y, Zhao D, Zhao W, Zheng Y, Zhou M, Zhu D, Zimmermann E, Zuñiga Cisneros J
(A1 Refereed original research article in a scientific journal)
TV viewing and subclinical cardiac diastolic dysfunction in early midlife. The Cardiovascular Risk in Young Finns Study. (2016) Helajärvi H, Ruohonen S, Pahkala K, Heinonen OJ, Viikari J, Raitakari OT
(Other publication)
Twenty-eight genetic loci associated with ST-T-wave amplitudes of the electrocardiogram (2016)
- Human Molecular Genetics
Verweij N, Mateo Leach I, Isaacs A, Arking DE, Bis JC, Pers TH, Van Den Berg ME, Lyytikäinen LP, Barnett P, Wang X; LifeLines Cohort Study., Soliman EZ, Van Duijn CM, Kähönen M, Van Veldhuisen DJ, Kors JA, Raitakari OT, Silva CT, Lehtimäki T, Hillege HL, Hirschhorn JN, Boyer LA, Van Gilst WH, Alonso A, Sotoodehnia N, Eijgelsheim M, De Boer RA, De Bakker PI, Franke L, Van Der Harst P
(A1 Refereed original research article in a scientific journal)
Whole-Exome Sequencing Identifies Loci Associated with Blood Cell Traits and Reveals a Role for Alternative GFI1B Splice Variants in Human Hematopoiesis (2016)
- American Journal of Human Genetics
Polfus LM, Khajuria RK, Schick UM, Pankratz N, Pazoki R, Brody JA, Chen MH, Auer PL, Floyd JS, Huang J, Lange L, van Rooij FJA, Gibbs RA, Metcalf G, Muzny D, Veeraraghavan N, Walter K, Chen L, Yanek L, Becker LC, Peloso GM, Wakabayashi A, Kals M, Metspalu A, Esko T, Fox K, Wallace R, Franceschini N, Matijevic N, Rice KM, Bartz TM, Lyytikainen LP, Kahonen M, Lehtimaki T, Raitakari OT, Li-Gao R, Mook-Kanamori DO, Lettre G, van Duijn CM, Franco OH, Rich SS, Rivadeneira F, Hofman A, Uitterlinden AG, Wilson JG, Psaty BM, Soranzo N, Dehghan A, Boerwinkle E, Zhang XL, Johnson AD, O'Donnell CJ, Johnsen JM, Reiner AP, Ganesh SK, Sankaran VG
(A1 Refereed original research article in a scientific journal)
Worldwide trends in diabetes since 1980: a pooled analysis of 751 population-based studies with 4.4 million participants (2016)
- Lancet
Zhou B, Lu Y, Hajifathalian K, Bentham J, Di Cesare M, Danaei G, Bixby H, Cowan MJ, Ali MK, Taddei C, Lo WC, Reis-Santos B, Stevens GA, Riley LM, Miranda JJ, Bjerregaard P, Rivera JA, Fouad HM, Ma GS, Mbanya JCN, McGarvey ST, Mohan V, Onat A, Ramachandran A, Ben Romdhane H, Paciorek CJ, Bennett JE, Ezzati M, Abdeen ZA, Kadir KA, Abu-Rmeileh NM, Acosta-Cazares B, Adams R, Aekplakorn W, Aguilar-Salinas CA, Agyemang C, Ahmadvand A, Al-Othman AR, Alkerwi A, Amouyel P, Amuzu A, Andersen LB, Anderssen SA, Anjana RM, Aounallah-Skhiri H, Aris T, Arlappa N, Arveiler D, Assah FK, Avdicova M, Azizi F, Balakrishna N, Bandosz P, Barbagallo CM, Barcelo A, Batieha AM, Baur LA, Ben Romdhane H, Benet M, Bernabe-Ortiz A, Bharadwaj S, Bhargava SK, Bi YF, Bjerregaard P, Bjertness E, Bjertness MB, Bjokelund C, Blokstra A, Bo S, Boehm BO, Boissonnet CP, Bovet P, Brajkovich I, Breckenkamp J, Brenner H, Brewster LM, Brian GR, Bruno G, Bugge A, de Leon AC, Can G, Candido APC, Capuano V, Carlsson AC, Carvalho MJ, Casanueva FF, Casas JP, Caserta CA, Castetbon K, Chamukuttan S, Chaturvedi N, Chen CJ, Chen FF, Chen SH, Cheng CY, Chetrit A, Chiou ST, Cho Y, Chudek J, Cifkova R, Claessens F, Concin H, Cooper C, Cooper R, Costanzo S, Cottel D, Cowell C, Crujeiras AB, D'Arrigo G, Dallongeville J, Dankner R, Dauchet L, de Gaetano G, De Henauw S, Deepa M, Dehghan A, Deschamps V, Dhana K, Di Castelnuovo AF, Djalalinia S, Doua K, Drygas W, Du Y, Dzerve V, Egbagbe EE, Eggertsen R, El Ati J, Elosua R, Erasmus RT, Erem C, Ergor G, Eriksen L, Escobedo-de la Pena J, Fall CH, Farzadfar F, Felix-Redondo FJ, Ferguson TS, Fernandez-Berges D, Ferrari M, Ferreccio C, Feskens EJM, Finn JD, Foger B, Foo LH, Forslund AS, Fouad HM, Francis DK, Franco MD, Franco OH, Frontera G, Furusawa T, Gaciong Z, Garnett SP, Gaspoz JM, Gasull M, Gates L, Geleijnse JM, Ghasemian A, Ghimire A, Giampaoli S, Gianfagna F, Giovannelli J, Giwercman A, Gross MG, Rivas JPG, Gorbea MB, Gottrand F, Grafnetter D, Grodzicki T, Grontved A, Gruden G, Gu DF, Guan OP, Guerrero R, Guessous I, Guimaraes AL, Gutierrez L, Hambleton IR, Hardy R, Kumar RH, Hata J, Heidemann C, Herrala S, Hihtaniemi IT, Ho SY, Ho SC, Hofman A, Hormiga CM, Horta BL, Houti L, Howitt C, Htay TT, Htet AS, Htike MMT, Htike MMT, Hu Y, Hussieni AS, Huybrechts I, Hwalla N, Iacoviello L, Iannone AG, Ibrahim MM, Ikeda N, Ikram MA, Irazola VE, Islam M, Iwasaki M, Jacobs JM, Jafar T, Jamil KM, Jasienska G, Jiang CQ, Jonas JB, Joshi P, Kafatos A, Kalter-Leibovici O, Kasaeian A, Katz J, Kaur P, Kavousi M, Kelishadi R, Kengne AP, Kersting M, Khader YS, Khalili D, Khang YH, Kiechl S, Kim J, Kolsteren P, Kratzer W, Kromhout D, Kujala UM, Kula K, Kyobutungi C, Laatikainen T, Lachat C, Laid Y, Lam TH, Landrove O, Lanska V, Lappas G, Laxmaiah A, Leclercq C, Lee J, Lee J, Lehtimaki T, Lekhraj R, Leon-Munoz LM, Li YP, Lim WY, Lima-Costa MF, Lin HH, Lin X, Lissner L, Lorbeer R, Lozano JE, Luksiene D, Lundqvist A, Lytsy P, Ma GS, Machado-Coelho GLL, Machi S, Maggi S, Magliano DJ, Makdisse M, Rao KM, Manios Y, Manzato E, Margozzini P, Marques-Vidal P, Martorell R, Masoodi SR, Mathiesen EB, Matsha TE, Mbanya JCN, McFarlane SR, McGarvey ST, McLachlan S, McNulty BA, Mediene-Benchekor S, Meirhaeghe A, Menezes AMB, Merat S, Meshram II, Mi J, Miquel JF, Miranda JJ, Mohamed MK, Mohammad K, Mohammadifard N, Mohan V, Yusoff MFM, Moller NC, Molnar D, Mondo CK, Morejon A, Moreno LA, Morgan K, Moschonis G, Mossakowska M, Mostafa A, Mota J, Motta J, Mu TT, Muiesan ML, Muller-Nurasyid M, Mursu J, Nagel G, Namesna J, Nang EEK, Nangia VB, Navarrete-Munoz EM, Ndiaye NC, Nenko I, Nervi F, Nguyen ND, Nguyen QN, Nieto-Martinez RSE, Ning G, Ninomiya T, Noale M, Noto D, Al Nsour M, Ochoa-Aviles AM, Oh K, Onat A, Ordunez P, Osmond C, Otero JA, Owusu-Dabo E, Pahomova E, Palmieri L, Panda-Jonas S, Panza F, Parsaeian M, Peixoto SV, Peltonen M, Peters A, Peykari N, Pham ST, Pilav A, Pitakaka F, Piwonska A, Piwonski J, Plans-Rubio P, Porta M, Portegies MLP, Poustchi H, Pradeepa R, Price JF, Punab M, Qasrawi RF, Qorbani M, Radisauskas R, Rahman M, Raitakari O, Rao SR, Ramachandran A, Ramke J, Ramos R, Rampal S, Rathmann W, Redon J, Reganit PFM, Rigo F, Robinson SM, Robitaille C, Rodriguez-Artalejo F, Rodriguez-Perez MD, Rodriguez-Villamizar LA, Rojas-Martinez R, Ronkainen K, Rosengren A, Rubinstein A, Rui O, Ruiz-Betancourt BS, Horimoto ARVR, Rutkowski M, Sabanayagam C, Sachdev HS, Saidi O, Sakarya S, Salanave B, Salonen JT, Salvetti M, Sanchez-Abanto J, Santos D, dos Santos RN, Santos R, Saramies JL, Sardinha LB, Sarrafzadegan N, Saum KU, Scazufca M, Schargrodsky H, Scheidt-Nave C, Sein AA, Sharma SK, Shaw JE, Shibuya K, Shin Y, Shiri R, Siantar R, Sibai AM, Simon M, Simons J, Simons LA, Sjostrom M, Slowikowska-Hilczer J, Slusarczyk P, Smeeth L, Snijder MB, So HK, Sobngwi E, Soderberg S, Solfrizzi V, Sonestedt E, Soumare A, Staessen JA, Stathopoulou MG, Steene-Johannessen J, Stehle P, Stein AD, Stessman J, Stockl D, Stokwiszewski J, Stronks K, Strufaldi MW, Sun CA, Sundstrom J, Sung YT, Suriyawongpaisal P, Sy RG, Tai ES, Tamosiunas A, Tang L, Tarawneh M, Tarqui-Mamani CB, Taylor A, Theobald H, Thijs L, Thuesen BH, Tolonen HK, Tolstrup JS, Topbas M, Torrent M, Traissac P, Trinh OTH, Tulloch-Reid MK, Tuomainen TP, Turley ML, Tzourio C, Ueda P, Ukoli FAM, Ulmer H, Uusitalo HMT, Valdivia G, Valvi D, van Rossem L, van Valkengoed IGM, Vanderschueren D, Vanuzzo D, Vega T, Velasquez-Melendez G, Veronesi G, Verschuren WMM, Verstraeten R, Viet L, Vioque J, Virtanen JK, Viswanathan B, Vollenweider P, Voutilainen S, Vrijheid M, Wade AN, Wagner A, Walton J, Mohamud WNW, Wang F, Wang MD, Wang Q, Wang YX, Wannamethee SG, Weerasekera D, Whincup PH, Widhalm K, Wijga AH, Wilks RJ, Willeit J, Wilsgaard T, Wojtyniak B, Wong TY, Woo J, Woodward M, Wu FC, Wu SL, Xu HQ, Yan WL, Yang XG, Ye XW, Yoshihara A, Younger-Coleman NO, Zambon S, Zargar AH, Zdrojewski T, Zhao WH, Zheng YF, Cisneros JZ
(A1 Refereed original research article in a scientific journal)
Activated immune-inflammatory pathways are associated with long-standing depressive symptoms: Evidence from gene-set enrichment analyses in the Young Finns Study (2015)
- Journal of Psychiatric Research
Elovainio M, Taipale T, Seppala I, Mononen N, Raitoharju E, Jokela M, Pulkki-Raback L, Illig T, Waldenberger M, Hakulinen C, Hintsa T, Kivimaki M, Kahonen M, Keltikangas-Jarvinen L, Raitakari O, Lehtimaki T
(A1 Refereed original research article in a scientific journal)
Adolescence physical activity is associated with higher tibial pQCT bone values in adulthood after 28-years of follow-up The Cardiovascular Risk in Young Finns Study (2015)
- BONE
Tolonen S, Sievanen H, Mikkila V, Telama R, Oikonen M, Laaksonen M, Viikari J, Kahonen M, Raitakari OT
(A1 Refereed original research article in a scientific journal)
Adult dyslipidemia prediction is improved by repeated measurements in childhood and young adulthood. The Cardiovascular Risk in Young Finns Study (2015)
- Atherosclerosis
Nuotio J, Oikonen M, Magnussen CG, Viikari JSA, Hutri-Kahonen N, Jula A, Thomson R, Sabin MA, Daniels SR, Raitakari OT, Juonala M
(A1 Refereed original research article in a scientific journal)
Adulthood temperament and educational attainment: A population-based cohort study (2015)
- Learning and Instruction
Mullola S, Hintsanen M, Elovainio M, Pulkki-Raback L, Lipsanen J, Josefsson K, Lehtimaki T, Raitakari OT, Keltikangas-Jarvinen L
(A1 Refereed original research article in a scientific journal)
A Genome-Wide Association Study of a Biomarker of Nicotine Metabolism (2015)
- PLoS Genetics
Loukola A, Buchwald J, Gupta R, Palviainen T, Hallfors J, Tikkanen E, Korhonen T, Ollikainen M, Sarin AP, Ripatti S, Lehtimaki T, Raitakari O, Salomaa V, Rose RJ, Tyndale RF, Kaprio J
(A1 Refereed original research article in a scientific journal)
A genome-wide expression quantitative trait loci analysis of proprotein convertase subtilisin/kexin enzymes identifies a novel regulatory gene variant for FURIN expression and blood pressure (2015)
- Human Genetics
Turpeinen H, Seppala I, Lyytikainen LP, Raitoharju E, Hutri-Kahonen N, Levula M, Oksala N, Waldenberger M, Klopp N, Illig T, Mononen N, Laaksonen R, Raitakari O, Kahonen M, Lehtimaki T, Pesu M
(A1 Refereed original research article in a scientific journal)
A novel common variant in DCST2 is associated with length in early life and height in adulthood (2015)
- Human Molecular Genetics
van der Valk RJP, Kreiner-Moller E, Kooijman MN, Guxens M, Stergiakouli E, Saaf A, Bradfield JP, Geller F, Hayes MG, Cousminer DL, Korner A, Thiering E, Curtin JA, Myhre R, Huikari V, Joro R, Kerkhof M, Warrington NM, Pitkanen N, Ntalla I, Horikoshi M, Veijola R, Freathy RM, Teo YY, Barton SJ, Evans DM, Kemp JP, St Pourcain B, Ring SM, Smith GD, Bergstrom A, Kull I, Hakonarson H, Mentch FD, Bisgaard H, Chawes B, Stokholm J, Waage J, Eriksen P, Sevelsted A, Melbye M, van Duijn CM, Medina-Gomez C, Hofman A, de Jongste JC, Taal HR, Uitterlinden AG, Armstrong LL, Eriksson J, Palotie A, Bustamante M, Estivill X, Gonzalez JR, Llop S, Kiess W, Mahajan A, Flexeder C, Tiesler CMT, Murray CS, Simpson A, Magnus P, Sengpiel V, Hartikainen AL, Keinanen-Kiukaanniemi S, Lewin A, Alves ADC, Blakemore AI, Buxton JL, Kaakinen M, Rodriguez A, Sebert S, Vaarasmaki M, Lakka T, Lindi V, Gehring U, Postma DS, Ang W, Newnham JP, Lyytikainen LP, Pahkala K, Raitakari OT, Panoutsopoulou K, Zeggini E, Boomsma DI, Groen-Blokhuis M, Ilonen J, Franke L, Hirschhorn JN, Pers TH, Liang L, Huang J, Hocher B, Knip M, Saw SM, Holloway JW, Melen E, Grant SFA, Feenstra B, Lowe WL, Widen E, Sergeyev E, Grallert H, Custovic A, Jacobsson B, Jarvelin MR, Atalay M, Koppelman GH, Pennell CE, Niinikoski H, Dedoussis GV, Mccarthy MI, Frayling TM, Sunyer J, Timpson NJ, Rivadeneira F, Bonnelykke K, Jaddoe VWV
(A1 Refereed original research article in a scientific journal)
Association of adiponectin with adolescent cardiovascular health in a dietary intervention study (2015)
- Journal of Pediatrics
Jaakkola J, Pahkala K, Viitala M, Rönnemaa T, Viikari J, Niinikoski H, Lagström H, Jula A, Simell O, Raitakari O.
(A1 Refereed original research article in a scientific journal)
Biological interpretation of genome-wide association studies using predicted gene functions (2015)
- Nature Communications
Pers TH, Karjalainen JM, Chan Y, Westra HJ, Wood AR, Yang J, Lui JC, Vedantam S, Gustafsson S, Esko T, Frayling T, Speliotes EK, Boehnke M, Raychaudhuri S, Fehrmann RS, Hirschhorn JN, Franke L.; Genetic Investigation of ANthropometric Traits (GIANT) Consortium
(A1 Refereed original research article in a scientific journal)
Childhood 25-OH Vitamin D Levels and Carotid Intima-Media Thickness in Adulthood: The Cardiovascular Risk in Young Finns Study (2015)
- Journal of Clinical Endocrinology and Metabolism
Juonala M, Voipio A, Pahkala K, Viikari JSA, Mikkila V, Kahonen M, Hutri-Kahonen N, Jula A, Burgner D, Sabin MA, Marniemi J, Loo BM, Laitinen T, Jokinen E, Taittonen L, Magnussen CG, Raitakari OT
(A1 Refereed original research article in a scientific journal)