Petri Susi
PhD, docent (in molecular virology at University of Turku and in plant cell biology and biotechnology at University of Helsinki)
pesusi@utu.fi +358 29 450 4556 +358 46 922 7336 Kiinamyllynkatu 10 Turku Office: D7062 ORCID identifier: https://orcid.org/0000-0002-9245-3271 |
Picornavirus; enterovirus; rhinovirus; parechovirus; virus evolution; bioinformatics; respiratory pathogens; clinical virology; diagnostics; protein production technologies; bioprocesses; cell culture techniques; molecular biology; gene technology; biosecurity; research data management;
For three years I studied biochemistry as major subject at University of Turku (Turku, Finland) just to end up to graduate with MSc degree in biology in 1994. The following five years (1995-1999) I worked as graduate student at University of Helsinki (Helsinki, Finland; with prof. Eija Pehu and Dr. Kirsi Lehto), Agrotechnological Research Institute (Wageningen, Netherlands; with Dr. Chris van der Schoot) and The James Hutton Institute (Dundee, UK; with Dr. Lesley Torrance) to finalize my PhD degree in the field of plant virology. As a post-doc, I did a short visit to cancer cell biology in Turku Bioscience - Turku Centre for Biotechnology (in 2000; with Dr. Päivi Koskinen), before securing four-year personal funding as post-doctoral researcher of Academy of Finland. I worked with FLP/FRT gene editing system in plants with a twist to plant virus movement processes in Joint Biotechnology Laboratory at University of Turku in 2001-2004. Following that period, I made a slight career turn from plant virology to human picornavirus research, and joined the group of prof. Timo Hyypiä to become a university staff member (Institute of Biomedicine, Faculty of Medicine, University of Turku). Currently, I am in a position of university lecturer in medical biotechnology and microbiology. My work history also includes research visits to diagnostic companies in Finland (2015 and 2017) and abroad (2015), two years as project manager at Turku University of Applied Sciences (2012-2013), and expert work in Tykslab clinical virology unit (2006-2012). I have co-founded two start-up companies.
My research has always been connected to molecular biology, microbiology and biotechnology. My current research focuses on picornavirus evolution, tropism, pathogenicity and diagnostics. I am particularly interested in the relationship between picornavirus genome evolution, cellular infectivity and disease mechanisms, which are the key elements in therapy development. Current projects include NGS sequencing of human picornaviruses, receptor search for entero- and parechoviruses, cell tropism of Rigvir oncolytic echovirus and development of novel diagnostics to rhinoviruses in SPARK Finland program.
- Cytolytic Properties and Genome Analysis of Rigvir® Oncolytic Virotherapy Virus and Other Echovirus 7 Isolates (2022)
- Viruses
(Refereed journal article or data article (A1)) - Special Issue: Virus Receptors and Viral Tropism (2022)
- Viruses
(Article or data-article in scientific journal (B1)) - Enteroviruses (Picornaviridae) (2021) Encyclopedia of Virology Savolainen-Kopra Carita, Blomqvist Soile, Susi Petri
(Article in a professional research book (D2)) - Monoclonal antibody against VP0 recognizes a broad range of human parechoviruses (2021)
- Journal of Virological Methods
(Refereed journal article or data article (A1)) - Recommendations for the introduction of metagenomic high-throughput sequencing in clinical virology, part I: Wet lab procedure (2021)
- Journal of Clinical Virology
(Refereed journal article or data article (A1)) - Aseptic meningitis outbreak associated with echovirus 4 in Northern Europe in 2013-2014 (2020)
- Journal of Clinical Virology
(Refereed journal article or data article (A1)) - Pikornavirukset (2020) Mikrobiologia - Mikrobiologia, immunologia ja infektiosairaudet, kirja 1 Susi Petri, Peltola Ville, Hyöty Heikki
(Article in a professional research book (D2)) - Recombination Events and Conserved Nature of Receptor Binding Motifs in Coxsackievirus A9 Isolates (2020)
- Viruses
(Refereed journal article or data article (A1)) - Special Issue "Human Picornaviruses" (2020)
- Viruses
(Article or data-article in scientific journal (B1)) - Detection of human rhinoviruses by reverse transcription strand invasion based amplification method (RT-SIBA) (2019)
- Journal of Virological Methods
(Refereed journal article or data article (A1)) - Progress in human picornavirus research: New findings from the AIROPico consortium (2019)
- Antiviral Research
(Refereed journal article or data article (A1)) - Genome sequences of RIGVIR oncolytic virotherapy virus and five other echovirus 7 isolates (2018)
- Genome Announcements
(Refereed journal article or data article (A1)) - Recommendations for enterovirus diagnostics and characterisation within and beyond Europe (2018)
- Journal of Clinical Virology
(Refereed review article in scientific journal (A2)) - Diagnosis of respiratory tract infections caused by human bocavirus 1 (2017)
- Clinical Laboratory International
(Article or data-article in scientific journal (B1)) - Obatoclax inhibits alphavirus membrane fusion by neutralizing the acidic environment of endocytic compartments (2017)
- Antimicrobial Agents and Chemotherapy
(Refereed journal article or data article (A1)) - Detection and monitoring of human bocavirus 1 infection by a new rapid antigen test (2016)
- New Microbes and New Infections
(Refereed journal article or data article (A1)) - Human Parechovirus 1 Infection Occurs via alpha V beta 1 Integrin (2016)
- PLoS ONE
(Refereed journal article or data article (A1)) - Integrins are not essential for entry of coxsackievirus A9 into SW480 human colon adenocarcinoma cells (2016)
- Virology Journal
(Refereed journal article or data article (A1)) - Role of Heparan Sulfate in Cellular Infection of Integrin-Binding Coxsackievirus A9 and Human Parechovirus 1 Isolates (2016)
- PLoS ONE
(Refereed journal article or data article (A1)) - Therapeutic Use of Native and Recombinant Enteroviruses (2016)
- Viruses
(Refereed review article in scientific journal (A2))