Eeva-Christine Brockmann
PhD
eechbr@utu.fi +358 29 450 4590 +358 50 345 9103 Kiinamyllynkatu 10 Turku : D6020 |
Phage display; antibodies; antibody engineering; recombinant antibody libraries; immunoassays; diagnostics; molecular biology; protein expression and purification; antibody affinity and stability
- Plasma CHI3L1 associates with brain volume loss and glial activation in multiple sclerosis (2025)
- Journal of Neurology, Neurosurgery and Psychiatry
- Fully human monoclonal antibody targeting the cysteine-rich substrate-interacting region of ADAM17 on cancer cells (2024)
- Biomedicine and Pharmacotherapy
- Plasma CHI3L1 associates with increased TSPO-PET measurable microglial activation in patients with progressive multiple sclerosis (2024)
- Multiple Sclerosis
- Isolation and functional analysis of phage-displayed antibody fragments targeting the staphylococcal superantigen-like proteins (2023)
- MicrobiologyOpen
- Isolation and characterization of phage display-derived scFv antibodies against human parechovirus 1 VP0 protein (2022)
- Scientific Reports
- Combinatorial mutagenesis with alternative CDR-L1 and-H2 loop lengths contributes to affinity maturation of antibodies (2021)
- New Biotechnology
- Recombinant Antibodies with Unique Specificities Allow for Sensitive and Specific Detection of Uncarboxylated Osteocalcin in Human Circulation (2020)
- Calcified Tissue International
- Identification and analysis of anti-HDL scFv-antibodies obtained from phage display based synthetic antibody library – Phage display derived HDL antibodies (2016)
- Clinical Biochemistry
- Chimeric recombinant antibody fragments in cardiac troponin I immunoassay (2015)
- Clinical Biochemistry
- Phage display aided improvement of a unique prostate-specific antigen (PSA) antibody unreactive with Lys(145)-Lys(146) internally cleaved forms (2015)
- Journal of Immunological Methods
- Lactobacillus helveticus MIMLh5-specific antibodies for detection of S-layer protein in Grana Padano protected-designation-of-origin cheese (2014)
- Applied and Environmental Microbiology
- Two ScFv antibody libraries derived from identical VLVH framework with different binding site designs display distinct binding profiles (2013)
- Protein Engineering, Design and Selection
- Primer Extension Mutagenesis Powered by Selective Rolling Circle Amplification (2012)
- PLoS ONE
- Selection of Stable scFv Antibodies by Phage Display (2012) Antibody Engineering: Methods and Protocols, Second Edition Eeva-Christine Brockmann
- Synthetic single-framework antibody library integrated with rapid affinity maturation by V-L shuffling (2011)
- Protein Engineering, Design and Selection
- Use of high-capacity surface with oriented recombinant antibody fragments in a 5-min immunoassay for thyroid-stimulating hormone (2010)
- Analytical Biochemistry
UTU Research Portal