Sakari Hietanen

- Docent,
Faculty of Medicine (University of Turku)
- ,
Obstetrics and Gynaecology (Department of Clinical Medicine)

sakari.hietanen@utu.fi

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Targeting DNA Homologous Repair Proficiency With Concomitant Topoisomerase II and c-Abl Inhibition (2021)
- Frontiers in Oncology
Siddiqui Arafat, Tumiati Manuela, Joko Alia, Sandholm Jouko, Roering, Aakko Pia Sofia, Vainionpää Reetta, Kaipio Katja, Huhtinen Kaisa, Kauppi Liisa, Tuomela Johanna, Hietanen Sakari
A longitudinal analysis of CA125 glycoforms in the monitoring and follow up of high grade serous ovarian cancer (2020)
- Gynecologic Oncology
Liina Salminen, Nimrah Nadeem, Shruti Jain, Seija Grènman, Olli Carpén, Sakari Hietanen, Sinikka Oksa, Urpo Lamminmäki, Kim Pettersson, Kamlesh Gidwani, Kaisa Huhtinen, Johanna Hynninen
American Association for Cancer Research Special Conference on Advances in Ovarian Cancer Research Sep 13-16, 2019 Atlanta, GA, USA Abstracts (2020)
- Clinical Cancer Research
Oikkonen J, Sanz NC, Hakkinen A, Li YL, Schulman I, Kivikoski M, Huhtinen K, Hietanen S, Grenman SE, Hynninen J, Lehtonen R, Hautaniemi S
Analysis of single-cell RNA-seq data from ovarian cancer samples before and after chemotherapy links stress-related transcriptional profile with chemotherapy resistance (2020)
- bioRxiv
Zhang K, Erkan EP, Dai J, Andersson N, Kaipio K, Lamminen T, Mansuri N, Huhtinen K, Carpen O, Hynninen J, others
Author Correction: Virtual clinical trials identify effective combination therapies in ovarian cancer (2020)
- Scientific Reports
Kozłowska E, Vallius T, Hynninen J, Hietanen S, Färkkilä A, Hautaniemi S
Exploratory Analysis of CA125-MGL and –STn Glycoforms in the Differential Diagnostics of Pelvic Masses (2020)
- The Journal of Applied Laboratory Medicine
Liina Salminen, Nimrah Nadeem, Anne Lone Rolfsen, Anne Dørum, Teemu D Laajala, Seija Grènman, Sakari Hietanen, Taija Heinosalo, Antti Perheentupa, Matti Poutanen, Nils Bolstad, Olli Carpén, Urpo Lamminmäki, Kim Pettersson, Kamlesh Gidwani, Johanna Hynninen, Kaisa Huhtinen
Extracellular matrix proteins increase invasive growth and chemotherapy resistance of ovarian cancer cells (2020)
- Clinical Cancer Research
Pietila EA, Gonzales-Molina J, Moyano-Galceran L, Lehtinen L, Turunen P, Martins TS, Rantanen V, Hakkinen A, Jamalzadeh S, Zhang KY, Lamminen T, Kaipio K, Hynninen J, Hietanen S, Grenman S, Lehtonen R, Hautaniemi S, Carpen O, Lehti K, Lehti K
HE4 in the evaluation of tumor load and prognostic stratification of high grade serous ovarian carcinoma (2020)
- Acta Oncologica
Liina Salminen, Kamlesh Gidwani, Seija Grènman, Olli Carpén, Sakari Hietanen, Kim Pettersson, Kaisa Huhtinen, Johanna Hynninen
qSNE: quadratic rate t-SNE optimizer with automatic parameter tuning for large datasets (2020)
- Bioinformatics
Häkkinen A, Koiranen J, Casado J, Kaipio K, Lehtonen O, Petrucci E, Hynninen J, Hietanen S, Carpén O, Pasquini L, Biffoni M, Lehtonen R, Hautaniemi S
RNA-seq analysis of high-grade serous ovarian cancer patients before and after chemotherapy reveals chemoresistance-associated genes and pathways (2020)
- Clinical Cancer Research
Jamalzadeh S, Zhang KY, Hakkinen A, Huhtinen K, Hynninen J, Andersson N, Mansuri N, Carpen O, Erdogan E, Dai J, Vaharautio A, Hietanen S, Oikkonen J, Lehtonen R, Hautaniemi S
Singling out tumor heterogeneity and chemoresistance in high-grade serous ovarian cancer (2020)
- Clinical Cancer Research
Erkan EP, Dai J, Zhang KY, Kaipio K, Lamminen T, Mansuri N, Suominen L, Alkodsi A, Huhtinen K, Hietanen S, Hynninen J, Grenman S, Carpen O, Hautaniemi S, Vaharautio A
The feasibility of [F-18]EF5-PET/CT to image hypoxia in ovarian tumors: a clinical study (2020)
- EJNMMI Research
Maren Laasik, Johanna Hynninen, Sarita Forsback, Tommi Noponen, Marko Seppänen, Sakari Hietanen
Association of Vulvar Melanoma with Lichen Sclerosus (2019)
- Acta Dermato-Venereologica
Niina Hieta, Samu Kurki, Marjut Rintala, Jenni Söderlund, Sakari Hietanen, Katri Orte
Behavior of FDG-avid supradiaphragmatic lymph nodes in PET/CT throughout primary therapy in advanced serous epithelial ovarian cancer: a prospective study (2019)
- Cancer Imaging
Laasik M, Kemppainen J, Auranen A, Hietanen S, Grénman S, Seppänen M, Hynninen J
CtDNA profiling to predict prognosis and optimize treatment in high-grade serous ovarian cancer (2019)
- Clinical Cancer Research
Oikkonen J, Zhang KY, Salminen L, Huhtinen K, Schulman I, Andersson N, Carpen O, Hietanen S, Grenman S, Lehtonen R, Hynninen J, Farkkila A, Hautaniemi S
Decorin Expression in Human Vulva Carcinoma: Oncosuppressive Effect of Decorin cDNA Transduction on Carcinoma Cells (2019)
- Journal of Histochemistry and Cytochemistry
Marie C. Nyman, Anne B. Jokilammi, Pia C. Boström, Samu H. Kurki, Annele O. Sainio, Seija E. Grenman, Katri J. Orte, Sakari H. Hietanen, Klaus Elenius, Hannu T. Järveläinen
Niraparib plus bevacizumab versus niraparib alone for platinum-sensitive recurrent ovarian cancer (NSGO-AVANOVA2/ENGOT-ov24): a randomised, phase 2, superiority trial (2019)
- Lancet Oncology
Mirza MR, Lundqvist EA, Birrer M, Christensen RD, Nyvang GB, Malander S, Anttila M, Werner TL, Lund B, Lindahl G, Hietanen S, Peen U, Dimoula M, Roed H, Knudsen AO, Staff S, Vistisen AK, Bjorge L, Maenpaa JU
Open Source Infrastructure for Health Care Data Integration and Machine Learning Analyses (2019)
- JCO Clinical Cancer Informatics
Isoviita VM, Salminen L, Azar J, Lehtonen R, Roering P, Carpén O, Hietanen S, Grénman S, Hynninen J, Färkkilä A, Hautaniemi S
Prospective Longitudinal ctDNA Workflow Reveals Clinically Actionable Alterations in Ovarian Cancer (2019)
- JCO Precision Oncology
Oikkonen J, Zhang KY, Salminen L, Schulman I, Lavikka K, Andersson N, Ojanperä E, Hietanen S, Grenman S, Lehtonen R, Huhtinen K, Carpen O, Hynninen J, Färkkilä A, Hautaniemi S
Virtual clinical trials identify effective combination therapies in ovarian cancer (2019)
- Scientific Reports
Kozlowska E, Vallius T, Hynninen J, Hietanen S, Farkkila A, Hautaniemi S