Sakari Hietanen

- Docent,
Faculty of Medicine (University of Turku)
- ,
Obstetrics and Gynaecology (Department of Clinical Medicine)

sakari.hietanen@utu.fi

Publications

1 of 8

Dynamic and Ongoing De Novo L1 Retrotransposition Contributes to Genome Plasticity and Intrapatient Heterogeneity in Ovarian Cancer (2026)
- Cancer Research
Pradhan, Barun; Oikkonen, Jaana; Zhang, Kaiyang; Botto, Juan Manuel.; Eriksson, Minna R.; Sundaresan, Srividhya; Genç, Fatih; Pisanic, Thomas R.; Marin Falco, Matias; Li, Yilin; Pikkusaari, Sanna; Lavikka, Kari; Micoli, Giulia; Marchi, Giovanni; Muranen, Taru A.; Huhtinen, Kaisa; Vähärautio, Anna; Badge, Richard; Burns, Kathleen H.; Hietanen, Sakari; Hynninen, Johanna; Faulkner, Geoffrey J.; Hautaniemi, Sampsa; Kauppi, Liisa
(A1 Refereed original research article in a scientific journal)
Exploring survival-associated transcriptomic subtypes in ovarian cancer using RNAseq from FFPE tissues in a clinical trial cohort (2026)
- Translational Oncology
Kjeldsen, Maj K.; Bagger, Frederik Otzen; Roed, Henrik; Nyvang, Gitte-Bettina; Haslund, Charlotte Aaquist; Knudsen, Anja Oer; Motavaf, Anne Krejbjerg; Malander, Susanne; Anttila, Maarit; Lindahl, Gabriel; Maenpää, Johanna; Dimoula, Maria; Werner, Theresa; Iversen, Trine Zeeberg; Hietanen, Sakari; Fokdal, Lars; Dahlstrand, Hanna; Bjorge, Line; Birrer, Michael; Mirza, Mansoor Raza; Rossing, Maria
(A1 Refereed original research article in a scientific journal)
Pembrolizumab plus weekly paclitaxel in platinum-resistant recurrent ovarian cancer (ENGOT-ov65/KEYNOTE-B96): a multicentre, randomised, double-blind, phase 3 study (2026)
- Lancet
Colombo, Nicoletta; Zsiros, Emese; Parma, Gabriella; Rulli, Eliana; Sebastianelli, Alexandra; Bidzinski, Mariusz; Gallardo, Carlos; Matanes, Emad; Hasegawa, Kosei; Kose, Fatih; Magallanes-Maciel, Manuel; Herbertson, Rebecca A.; Ananda, Sumitra; Kroep, Judith R.; de Melo, Andreia Cristina; Debruyne, Philip R.; Kim, Jae-Weon; Sehouli, Jalid; Pierre, Marc-Edy; Hietanen, Sakari; Zamagni, Claudio; Lu, Xin; Monk, Bradley J.; Coleman, Robert L.; Peng, Xuan; Yamada, Karin; Bogusz, Agata M.; De La Motte Rouge, Thibault; Wu, Xiaohua; ENGOT-ov65/KEYNOTE-B96 investigators
(A1 Refereed original research article in a scientific journal)
Decoding the Genomic and Functional Landscape of Emerging Subtypes in Ovarian Cancer (2025)
- Cancer Discovery
Micoli, Giulia; Lavikka, Kari; Li, Yilin; Pirttikoski, Anna; Afenteva, Daria; Senkowski, Wojciech; Marchi, Giovanni; Vähärautio, Anna; Muranen, Taru A.; Joutsiniemi, Titta; Hietanen, Sakari; Virtanen, Anni; Wennerberg, Krister; Hynninen, Johanna; Oikkonen, Jaana; Hautaniemi, Sampsa
(A1 Refereed original research article in a scientific journal)
Genetic predictors of unexpected recurrence in low-risk endometrial cancer: A comprehensive genomic analysis reveals FGFR2 as a risk factor and a rare fatal POLE-mutated recurrence (2025)
- Gynecologic Oncology
Mettälä, Tuukka; Joutsiniemi, Titta; Huvila, Jutta; Hietanen, Sakari
(A1 Refereed original research article in a scientific journal)
Geneva Homologous Recombination Deficiency Test Is Predictive of Survival Benefit From Olaparib and Bevacizumab Maintenance in Ovarian Cancer (2025)
- JCO Precision Oncology
Christinat, Yann; Labidi-Galy, Intidhar; Ho, Liza; Clement, Sophie; Genestie, Catherine; Sehouli, Jalid; Cinieri, Saverio; Gonzalez-Martin, Antonio; Kolovetsiou-Kreiner, Vassiliki; Fujiwara, Keiichi; Von Gorp, Toon; Tognon, Germana; Hietanen, Sakari; Heinzelmann-Schwarz, Viola; Ray-Coquard, Isabelle; Pujade-Lauraine, Eric; Mckee, Thomas A.
(A1 Refereed original research article in a scientific journal)
HR-SC—an academic-developed machine learning framework to classify HRD-positive ovarian cancer patients and predict sensitivity to olaparib. (2025)
- ESMO Open
Beltrame, L.; Mannarino, L.; Sergi, A.; Velle, A.; Treilleux, I.; Pignata, S.; Paracchini, L.; Harter, P.; Scambia, G.; Perrone, F.; González-Martin, A.; Berger, R.; Arenare, L.; Hietanen, S.; Califano, D.; Derio, S.; Van Gorp, T.; Dalessandro, M.L.; Fujiwara, K.; Provansal, M.; Lorusso, D.; Buderath, P.; Masseroli, M.; Ray-Coquard, I.; Pujade-Lauraine, E.; Romualdi, C.; D’Incalci, M.; Marchini S.
(A1 Refereed original research article in a scientific journal)
Multi-omics analysis reveals the attenuation of the interferon pathway as a driver of chemo-refractory ovarian cancer (2025)
- Cell Reports Medicine
Afenteva, Daria; Yu, Rong; Rajavuori, Anna; Salvadores, Marina; Launonen, Inga-Maria; Lavikka, Kari; Zhang, Kaiyang; Pirttikoski, Anna; Marchi, Giovanni; Jamalzadeh, Sanaz; Isoviita, Veli-Matti; Li, Yilin; Micoli, Giulia; Erkan, Erdogan Pekcan; Falco, Matias M.; Ungureanu, Daniela; Lahtinen, Alexandra; Oikkonen, Jaana; Hietanen, Sakari; Vähärautio, Anna; Sur, Inderpreet; Virtanen, Anni; Färkkilä, Anniina; Hynninen, Johanna; Muranen, Taru A.; Taipale, Jussi; Hautaniemi, Sampsa
(A1 Refereed original research article in a scientific journal)
Predictive value of BRCA1/RAD51C methylation in HGSOC – An ancillary study of the PAOLA-1/ENGOT-ov25 phase 3 trial (2025)
- European Journal of Cancer
Blons, H.; Abdelli, J.; Landman, S.; Taly, V.; Mulot, C.; Laurent-Puig, P.; You, B.; Harter, P.; Lorusso, D.; García-García, Y.; Polterauer, S.; Hietanen, S.; Colombo, N.; Vergote, I.; Kobayashi, H.; De La Motte Rouge, T.; Buderath, P.; Cecere, S.C.; Bataillon, G.; Pujade-Lauraine, E.; Ray-Coquard, I.
(A1 Refereed original research article in a scientific journal)
Beyond HRD status: Unraveling Genetic Variants Impacting PARP Inhibitor Sensitivity in Advanced Ovarian Cancer (2024)
- Cancer Research Communications
Kjeldsen, Maj K.; Jørgensen, Morten; Grønseth, Dina Sofie B.; Schønemann-Lund, Martin; Nyvang, Gitte-Bettina; Haslund, Charlotte Aaquist; Knudsen, Anja Oer; Motavaf, Anne Krejbjerg; Malander, Susanne; Anttila, Maarit; Lindahl, Gabriel; Mäenpää, Johanna; Dimoula, Maria; Werner, Theresa L; Iversen, Trine Zeeberg; Hietanen, Sakari; Fokdal, Lars; Dahlstrand, Hanna; Bjorge, Line; Birrer, Michael J.; Mirza, Mansoor R.; Rossing, Maria
(A1 Refereed original research article in a scientific journal)