Obada Al-Zghool
Doctoral Candidate
obalzg@utu.fi Tykistökatu 6 A Turku Työhuone: 4129 You can also reach me on obada.zghoul@yahoo.com ORCID-tunniste: https://orcid.org/0000-0002-6166-4957 |
Neurodegenerative diseases, mainly Alzheimer's and Parkinson's diseases.
Obada is a pharmacist by education, he obtained his bachelor's degree from Philadelphia University. Later on he decided to continue his higher education and pursue an academic career, so he moved to Finland in 2015 and obtained his M.Sc degree in Drug Discovery and Development.
Obada's master thesis aimed at characterizing novel PET tracer for imaging p-tau in Alzheimer's disease model. He obtained his master's degree in 2017 and thereafter has been a doctoral candidate at the preclinical imaging laboratory in Turku PET Center. Obada's research work is centered around biological evaluation of novel PET tracers.
The topic of my research is biological evaluation of novel PET tracers for imaging altered protein aggregates and neuroinflammatory markers in the central nervous system at in-vitro and preclinical settings
- Correction to: Glial reactivity in a mouse model of beta-amyloid deposition assessed by PET imaging of P2X7 receptor and TSPO using [11C]SMW139 and [18F]F-DPA (EJNMMI Research, (2024), 14, 1, (25), 10.1186/s13550-024-01085-7) (2024)
- EJNMMI Research
(O2 Muu julkaisu ) - Glial reactivity in a mouse model of beta-amyloid deposition assessed by PET imaging of P2X7 receptor and TSPO using [11C]SMW139 and [18F]F-DPA (2024)
- EJNMMI Research
(A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä ) - Preclinical development of radiopharmaceuticals for Alzheimer’s disease: Biological evaluation of (S)-[18F]THK5117 and [11C]SMW139 PET tracers in the APP/PS1-21 mouse model of Alzheimer’s disease (2024) Al-Zghool Obada
(G5 Artikkeliväitöskirja) - Novel plasma protein binding analysis method for a PET tracer and its radiometabolites: A case study with [11C]SMW139 to explain the high uptake of radiometabolites in mouse brain (2022)
- Journal of Pharmaceutical and Biomedical Analysis
(A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä ) - α-Synuclein Radiotracer Development and In Vivo Imaging: Recent Advancements and New Perspectives (2022)
- Movement Disorders
(A2 Vertaisarvioitu katsausartikkeli tieteellisessä lehdessä) - (S)-[18F]THK5117 brain uptake is associated with Aβ plaques and MAO-B enzyme in a mouse model of Alzheimer's disease (2021)
- Neuropharmacology
(A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä ) - [18F]F-DPA for the detection of activated microglia in a mouse model of Alzheimer's disease (2018)
- Nuclear Medicine and Biology
(A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä )
