Pauli Kallio
Ph.D.
pataka@utu.fi +358 29 450 4209 +358 50 339 6978 Itäinen Pitkäkatu 4 C Turku : 6038.1 : https://orcid.org/0000-0003-3590-9882 |
Synthetic biology; Cyanobacterial metabolic engineering; Molecular biology; Enzymology
Department of Life Technologies, Faculty of Technology
The research in our group (Synthetic Biology of Cyanobacteria) is focused on metabolic engineering and characterization of photosynthetic cyanobacteria. We aim to establish and use different synthetic biology approaches to enable more efficient metabolic engineering of the target strains. The ultimate objective is to develop novel biotechnological applications, which would allow solar-driven production of different carbon-based chemicals directly from CO2 – using photoautotrophic cyanobacterial cells as biological catalysts.
The research stems from the fundamental photosynthesis research carried out at Molecular Plant Biology, and covers different areas of molecular biology, microbiology and analytics.
Find more information on our group website at http://utu.fi/sbc
DIBT0084-3001 Kestävien bioteknisten prosessien perusteet
https://opas.peppi.utu.fi/fi/opintojakso/DIBT0084/87338
DIBT0607-3001 Scientific Writing in Biosciences
https://opas.peppi.utu.fi/fi/opintojakso/DIBT0607/91865
DIBT0604-3001 Technology Outreach
https://opas.peppi.utu.fi/fi/opintojakso/DIBT0604/88473
https://sites.utu.fi/technologyoutreach
DIBT0602 Microbial Metabolic Engineering I
https://opas.peppi.utu.fi/fi/opintojakso/DIBT0602/89496
DIBT0603 Microbial Metabolic Engineering - Practice
https://opas.peppi.utu.fi/fi/opintojakso/DIBT0603/89497
- A microbial platform for renewable propane synthesis based on a fermentative butanol pathway (2015)
- Biotechnology for Biofuels
- A synthetic O2 -tolerant butanol pathway exploiting native fatty acid biosynthesis in Escherichia coli (2015)
- Biotechnology and Bioengineering
- An engineered pathway for the biosynthesis of renewable propane (2014)
- Nature Communications
- Engineering Photobiological H2-Production (2014) Algal Biorefineries Linda Vuorijoki, Pauli Kallio, Patrik R. Jones
- Renewable Jet Fuel (2014)
- Current Opinion in Biotechnology
- Structural and Functional Analysis of Angucycline C-6 Ketoreductase LanV Involved in Landomycin Biosynthesis (2013)
- Biochemistry
- Tracing the Evolution of Angucyclinone Monooxygenases: Structural Determinants for C-12b Hydroxylation and Substrate Inhibition in PgaE (2013)
- Biochemistry
- Discovery of a Two-Component Monooxygenase SnoaW/SnoaL2 Involved in Nogalamycin Biosynthesis (2012)
- Chemistry and Biology
- Tailoring Enzymes Involved in the Biosynthesis of Angucyclines Contain Latent Context-Dependent Catalytic Activities (2012)
- Chemistry and Biology
- Flavoprotein Hydroxylase PgaE Catalyzes Two Consecutive Oxygen-Dependent Tailoring Reactions in Angucycline Biosynthesis (2011)
- Biochemistry
- Formation and hydrolysis of amide bonds by lipase A from Candida antarctica; exceptional features (2010)
- Organic and Biomolecular Chemistry
- A nested gene in Streptomyces bacteria encodes a protein involved in quaternary complex formation (2008) Kallio P, Liu ZL, Mantsala P, Niemi J, Metsa-Ketela M
- Sequential action of two flavoenzymes, PgaE and PgaM, in angucycline biosynthesis: Chemoenzymatic synthesis of gaudimycin C (2008)
- Chemistry and Biology
- Crystal structures of two aromatic hydroxylases involved in the early tailoring steps of angucycline biosynthesis (2007)
- Journal of Molecular Biology
- Crystal structure of the polyketide cyclase AknH with bound substrate and product analogue: Implications for catalytic mechanism and product stereoselectivity (2006) Kallio P, Sultana A, Niemi J, Mantsala P, Schneider G
- Structural genomics of the biosynthesis of polyketide antibiotics (2005)
- FEBS Journal
- Crystallization and preliminary crystallographic data of SnoaL, a polyketide cyclase in nogalamycin biosynthesis (2004)
- Acta Crystallographica Section D: Biological Crystallography
- Structure of the polyketide cyclase SnoaL reveals a novel mechanism for enzymatic aldol condensation (2004)
- EMBO Journal
