Meng Wang
Mona, Research Fellow, PhD
meng.me.wang@utu.fi ORCID-tunniste: https://orcid.org/0000-0002-4019-0289 |
Immunotherapy, Ocular Oncology, Biomarker Discovery, Bioinformatics
I completed my doctoral training through a joint project between the University of Turku and the Singapore Eye Research Institute (SERI), focused on developing a novel metastatic uveal melanoma model to investigate resistance mechanisms to immune checkpoint inhibitors. This work was part of an international collaboration involving SERI, the University of Turku, and the Liverpool Ocular Oncology Research Group (LOORG).
Currently, I work as a Research Fellow continuing translational research in tumor immunology and biomarker discovery, with a focus on precision medicine approaches for the diagnosis and management of diffuse large B-cell lymphoma (DLBCL) and metastatic melanoma. My work integrates single-cell genomics, transcriptomics, proteomics, and lipidomics, combined with in-house bioinformatics pipelines and artificial intelligence tools to analyze multi-omics data and drive clinically relevant insights across various specimen types.
- Genetic landscape of uveal melanoma in Southeast Asia: high 1q gains and unique patterns of metastasis risk (2025)
- Eye and Vision
(A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä ) - Epigenetic control of CD1D expression as a mechanism of resistance to immune checkpoint therapy in poorly immunogenic melanomas (2023)
- Frontiers in Immunology
(A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä ) - Resistance to immune checkpoint therapies by tumour-induced T-cell desertification and exclusion: key mechanisms, prognostication and new therapeutic opportunities (2023)
- British Journal of Cancer
(A2 Vertaisarvioitu katsausartikkeli tieteellisessä lehdessä) - Applying Single-Cell Technology in Uveal Melanomas: Current Trends and Perspectives for Improving Uveal Melanoma Metastasis Surveillance and Tumor Profiling (2021)
- Frontiers in Molecular Biosciences
(A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä ) - Cytologic and Molecular Diagnostics for Vitreoretinal Lymphoma: Current Approaches and Emerging Single-Cell Analyses (2021)
- Frontiers in Molecular Biosciences
(A2 Vertaisarvioitu katsausartikkeli tieteellisessä lehdessä) - PreservCyt Is an Optimal Fixative that Permits Cytologic and Molecular Analyses of Vitreoretinal Lymphoma Biopsies (2021)
- Ocular Immunology and Inflammation
(A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä ) - Single B-Cell Genomic Analyses Differentiate Vitreoretinal Lymphoma from Chronic Inflammation (2021)
- Ophthalmology: Journal of The American Academy of Ophthalmology
(A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä ) - Single-cell MYD88 sequencing of isolated B cells from vitreous biopsies aids vitreoretinal lymphoma diagnosis (2019)
- Blood
(B1 Vertaisarvioimaton kirjoitus tieteellisessä lehdessä )