Matej Oresic
Ph.D.
matej.oresic@utu.fi +358 29 450 3798 +358 46 923 3395 Tykistökatu 6 Turku ORCID-tunniste: https://orcid.org/0000-0002-2856-9165 |
Systems biology, exposome, bioinformatics, metabolomics, lipidomics, biophysics, systems medicine, computational biology
Professor Matej Orešič holds a PhD in biophysics from Cornell University (1999; Ithaca, NY, USA). He is professor of medicine, with specialization in systems medicine at Örebro University (Sweden) and a professor of biochemistry (metabolomics) at the University of Turku (Finland). Prof. Orešič’s main research areas include exposomics and metabolomics applications in biomedical research and systems medicine. He is particularly interested in the identification of environmental exposures (exposome) and disease processes associated with different metabolic phenotypes and the underlying mechanisms linking these processes with the development of specific disorders or their co-morbidities. Prof. Orešič also initiated the popular MZmine open-source project, which led to the development and release of popular software for metabolomics data processing. As of 2016, he was made a Lifetime Honorary Fellow of the Metabolomics Society. Professor Orešič currently serves as member of the Board of Directors of the Metabolomics Society and is one of the founders of the Nordic Metabolomics Society, previously serving as its chair of the board. In 2019, he co-chaired the 1st Gordon Research Conference on ‘Metabolomics and Human Health’ (Ventura, CA, USA). Previously, he also chaired the Keystone Symposium on Systems Biology of Lipid Metabolism (2015; Breckenridge, CO, USA). Professor Orešič currently coordinates Horizon Europe project “Inflammation in human early life: targeting impacts on life-course health – INITIALISE (https://initialise-project.eu/)”. He is also Co-Coordinator of the new Horizon Europe project “Investigation of endocrine-disrupting chemicals as contributors to progression of metabolic dysfunction-associated steatotic liver disease – EDC-MASLD (https://edc-masld.eu/)”.
Professor Orešič’s main research areas include exposomics and metabolomics applications in biomedical research and systems medicine. He is particularly interested in the identification of environmental exposures (exposome) and disease processes associated with different metabolic phenotypes and the underlying mechanisms linking these processes with the development of specific disorders or their co-morbidities. Prof. Orešič also initiated the popular MZmine open-source project, which led to the development and release of popular software for metabolomics data processing. Professor Orešič currently coordinates Horizon Europe project “Inflammation in human early life: targeting impacts on life-course health – INITIALISE (https://initialise-project.eu/)”. He is also Co-Coordinator of the new Horizon Europe project “Investigation of endocrine-disrupting chemicals as contributors to progression of metabolic dysfunction-associated steatotic liver disease – EDC-MASLD (https://edc-masld.eu/)”.
- The Role of Omic Technologies in the Study of the Human Gut Microbiome (2019) Reference Module in Food Science Partho Sen, Santosh Lamichhane, Alex M Dickens, Matej Orešič
(A3 Vertaisarvioitu kirjan tai muun kokoomateoksen osa) - A computational framework to integrate high-throughput ‘-omics’ datasets for the identification of potential mechanistic links (2018)
- Nature Protocols
(A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä ) - A longitudinal plasma lipidomics dataset from children who developed islet autoimmunity and type 1 diabetes (2018)
- Scientific Data
(A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä ) - Analysis of microbiota in first episode psychosis identifies preliminary associations with symptom severity and treatment response (2018)
- Schizophrenia Research
(A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä ) - Dynamics of Plasma Lipidome in Progression to Islet Autoimmunity and Type 1 Diabetes - Type 1 Diabetes Prediction and Prevention Study (DIPP) (2018)
- Scientific Reports
(A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä ) - Gut metabolome meets microbiome: A methodological perspective to understand the relationship between host and microbe (2018)
- Methods
(A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä ) - Lipidome as a predictive tool in progression to type 2 diabetes in Finnish men (2018)
- Metabolism
(A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä ) - MS-based lipidomics of human blood plasma: a community-initiated position paper to develop accepted guidelines (2018)
- Journal of Lipid Research
(A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä ) - Perspectives on systems modeling of human peripheral blood mononuclear cells (2018)
- Frontiers in Molecular Biosciences
(A2 Vertaisarvioitu katsausartikkeli tieteellisessä lehdessä) - Platform for systems medicine research and diagnostic applications in psychotic disorders-The METSY project (2018)
- European Psychiatry
(A2 Vertaisarvioitu katsausartikkeli tieteellisessä lehdessä) - Saturated Fat Is More Metabolically Harmful for the Human Liver Than Unsaturated Fat or Simple Sugars (2018)
- Diabetes Care
(A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä ) - Serum Metabolites Associated with Computed Tomography Findings after Traumatic Brain Injury (2018)
- Journal of Neurotrauma
(A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä ) - Serum, plasma and erythrocyte membrane lipidomes in infants fed formula supplemented with bovine milk fat globule membranes (2018)
- Pediatric Research
(A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä ) - Targeted Serum Metabolite Profiling Identifies Metabolic Signatures in Patients with Alzheimer's Disease, Normal Pressure Hydrocephalus and Brain Tumor (2018)
- Frontiers in Neuroscience
Hilkka Soininen, Tuulia Hyötyläinen, Cherlynn Basignani
(A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä ) - Use of Blood Biomarkers in the Assessment of Sports-Related Concussion-A Systematic Review in the Context of Their Biological Significance (2018)
- Clinical Journal of Sport Medicine
(A2 Vertaisarvioitu katsausartikkeli tieteellisessä lehdessä) - Harmonizing lipidomics: NIST interlaboratory comparison exercise for lipidomics using SRM 1950-Metabolites in Frozen Human Plasma (2017)
- Journal of Lipid Research
(A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä ) - Hypothalamic AMPK-ER Stress-JNK1 Axis Mediates the Central Actions of Thyroid Hormones on Energy Balance (2017)
- Cell Metabolism
(A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä ) - Identification of a plasma signature of psychotic disorder in children and adolescents from the Avon Longitudinal Study of Parents and Children (ALSPAC) cohort (2017)
- Translational Psychiatry
(A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä ) - Impaired hepatic lipid synthesis from polyunsaturated fatty acids in TM6SF2 E167K variant carriers with NAFLD (2017)
- Journal of Hepatology
(A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä ) - Lipidomics in biomedical research-practical considerations (2017)
- Biochimica et Biophysica Acta Molecular and Cell Biology of Lipids
(A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä )



