PhD Ivana Mikocziova - UTU Research Portal

Ivana Mikocziova
PhD

- Postdoctoral Researcher,
Turku Bioscience Centre (Independent units)

ivana.mikocziova@utu.fi

Office: 5022

ORCID identifier: https://orcid.org/0000-0003-2928-445X

Areas of expertise

Immunology; Single-cell omics; Spatial omics; Autoimmunity; T cells; B cells; Adaptive Immune Receptor Repertoires (AIRR)

Research community or research topic

InFLAMES Research Flagship

Biography

Postdoctoral researcher at the Single Cell Omics core facility (Turku Bioscience) & Single-cell Immunogemoics research group.

Research

My research focuses on adaptive immune cells in health and disease, and I am particularly interested in autoimmune and immune-mediated diseases. In the lab, I perform various single-cell omics and spatial omics experiments, with focus on transcriptomics. On the analysis side, I specialise in T cell receptor (TCR) and B cell receptor/antibody (BCR) repertoires, collectivelly also known as Adaptive Immune Receptor Repertoires (AIRR).

Teaching

Teaching:

BIOT1524_30004_1 Modernit bioteknologiat ja bioinformatiikka/Modern biotechnologies and bioinformatics (2023 - present)

BIOT2308 Omics Technologies and Bioinformatics

IFDM2001-3001 Methods of Immunological Research

Other teaching activities:

Single Cell Course Week | HiLIFE (Helsinki, Finland): "Single Cell Sequencing: Zooming in on 10x Genomics’ Chromium System"

Publications

Dynamics of T cell and B cell receptor repertoires in response to obesity in a murine model of
atherosclerosis (2024)
- European Journal of Immunology
Mikocziova, Ivana; Mikkola, Lea; Palani, Senthil; Roivainen, Anne; Hernández de Sande, Ana; Heinäniemi, Merja; Örd, Tiit; Kaikkonen, Minna U; Lönnberg, Tapio
(Abstract)
Obesity-induced changes in perivascular adipose tissue fibroblasts in a mouse model of atherosclerosis (2024)
- European Journal of Immunology
Mikkola, Lea; Mikocziova, Ivana; Piipponen, Minna; Valkonen, Mira; Fagersund, Jimmy; Palani, Senthil; Roivainen, Anne; Hernández de Sande, Ana; Heinäniemi, Merja; Ruusuvuori, Pekka; Örd, Tiit; Kaikkonen, Minna U; Lönnberg, Tapio
(Abstract)
Germline polymorphisms and alternative splicing of human immunoglobulin light chain genes (2021)
- iScience
Mikocziova Ivana, Peres Ayelet, Gidoni Moriah, Greiff Victor, Yaari Gur, Sollid Ludvig M.
(A1 Refereed original research article in a scientific journal)
Immunoglobulin germline gene variation and its impact on human disease (2021)
- Genes and Immunity
Mikocziova Ivana, Greiff Victor, Sollid Ludvig M
(A2 Refereed review article in a scientific journal )
Individualized VDJ recombination predisposes the available Ig sequence space (2021)
- Genome Research
Slabodkin Andrei, Chernigovskaya Maria, Mikocziova Ivana, Akbar Rahmad, Scheffer Lonneke, Pavlović Milena, Bashour Habib, Snapkov Igor, Mehta Brij Bhushan, Weber Cédric R., Gutierrez-Marcos Jose, Sollid Ludvig M., Haff Ingrid Hobæk, Sandve Geir Kjetil, Robert Philippe A., Greiff Victor
(A1 Refereed original research article in a scientific journal)
Polymorphisms in human immunoglobulin heavy chain variable genes and their upstream regions (2020)
- Nucleic Acids Research
Mikocziova I, Gidoni M, Lindeman I, Peres A, Snir O, Yaari G, Sollid LM
(A1 Refereed original research article in a scientific journal)
Mosaic deletion patterns of the human antibody heavy chain gene locus shown by Bayesian haplotyping (2019)
- Nature Communications
Gidoni M, Snir O, Peres A, Polak P, Lindeman I, Mikocziova I, Sarna VK, Lundin KEA, Clouser C, Vigneault F, Collins AM, Sollid LM, Yaari G
(A1 Refereed original research article in a scientific journal)