Pekka Patrikainen
PhD
ptpatr@utu.fi Itäinen Pitkäkatu 4 C Turku Office: 6049 ORCID identifier: https://orcid.org/0000-0002-4931-1817 |
Areas of expertise
Synthetic Biology, Synechocystis, Metabolic Engineering, Molecular Biology, Enzymology, Natural Product Biosynthesis
Synthetic Biology, Synechocystis, Metabolic Engineering, Molecular Biology, Enzymology, Natural Product Biosynthesis
Research
My research focuses on the metabolic engineering of cyanobacteria to enable their use as biotechnological host for production of variety of chemicals. Another focus area is the development of genetic tools which are required for efficient and predictable modification of these photosynthetic organisms. My research involves the use of molecular biology, microbiology and different analytical methods.
More information can be found from the website of our research group at https://utu.fi/sbc
Publications
- CyanoConstruct: simple platform for cyanobacterial expression construct assembly and translational tuning (2026)
- BMC Biotechnology
(A1 Refereed original research article in a scientific journal) - Redirecting photosynthetic electron flux in the cyanobacterium Synechocystis sp. PCC 6803 by the deletion of flavodiiron protein Flv3 (2019)
- Microbial Cell Factories
(A1 Refereed original research article in a scientific journal) - Comparison of orthologous cyanobacterial aldehyde deformylating oxygenases in the production of volatile C3-C7 alkanes in engineered E. coli (2017)
- Metabolic Engineering Communications
(A1 Refereed original research article in a scientific journal) - Engineering the cyanobacterium synechocystis Sp. PCC 6803 towards optimized solutions for future biotechnological applications (2017) Nagy C., Aro E., Kallio P., Patrikainen P., Thiel K., Dandapani H., Mulaku E., Kakko L.
(Other publication) - Structural and functional Studies of angucycline tailoring enzymes (2015) Patrikainen Pekka
(G5 Article dissertation ) - Structure-Based Engineering of Angucyclinone 6-Ketoreductases. (2014)
- Chemistry and Biology
(A1 Refereed original research article in a scientific journal) - Structural and Functional Analysis of Angucycline C-6 Ketoreductase LanV Involved in Landomycin Biosynthesis (2013)
- Biochemistry
(A1 Refereed original research article in a scientific journal) - Tracing the Evolution of Angucyclinone Monooxygenases: Structural Determinants for C-12b Hydroxylation and Substrate Inhibition in PgaE (2013)
- Biochemistry
(A1 Refereed original research article in a scientific journal) - Identification of Late-Stage Glycosylation Steps in the Biosynthetic Pathway of the Anthracycline Nogalamycin (2012)
- ChemBioChem
(A1 Refereed original research article in a scientific journal) - Tailoring Enzymes Involved in the Biosynthesis of Angucyclines Contain Latent Context-Dependent Catalytic Activities (2012)
- Chemistry and Biology
(A1 Refereed original research article in a scientific journal) - Flavoprotein Hydroxylase PgaE Catalyzes Two Consecutive Oxygen-Dependent Tailoring Reactions in Angucycline Biosynthesis (2011)
- Biochemistry
(A1 Refereed original research article in a scientific journal) - Structure of Collagen Receptor Integrin alpha I-1 Domain Carrying the Activating Mutation E317A (2011)
- Journal of Biological Chemistry
(A1 Refereed original research article in a scientific journal)
UTU Research Portal