Megan Chastney - UTU Research Portal

Megan Chastney

- Postdoctoral Researcher,
Turku Bioscience Centre (Independent units)

megan.chastney@utu.fi

Calponin isoforms define the cell-type-specific organization and dynamics of actomyosin bundles (2025)
- Current Biology
Kokate, Shrikant B.; Oshin, Afsana T.; Chua, Xiang Le; Chastney, Megan; Biswas, Parijat; Kogan, Konstantin; Tomberg, Teemu; Ivaska, Johanna; Lappalainen, Pekka
EPLINα controls integrin recycling from Rab21 endosomes to drive breast cancer cell migration (2025)
- Developmental Cell
Jäntti, Niklas Z.; Moreno-Layseca, Paulina; Chastney, Megan R.; Dibus, Michal; Conway, James R.W.; Leppänen, Veli-Matti; Hamidi, Hellyeh; Eylmann, Kathrin; Oliveira-Ferrer, Leticia; Veltel, Stefan; Ivaska, Johanna
Integrin β1 activity controls colony morphology during human pluripotent stem cell state transitions (2025)
- Stem Cell Reports
Taskinen, Maria E.; Pasquier, Nicolas; Stubb, Aki; Joshi, Shreya; Chastney, Megan R.; Rasila, Paula; Vahlman, Sonja; Sokka, Joonas; Lönnberg, Tapio; Mikkola, Lea; Trokovic, Ras; Ivaska, Johanna
Regulation of cell dynamics by rapid integrin transport through the biosynthetic pathway (2025)
- Journal of Cell Biology
Lerche, Martina; Mathieu, Mathilde; Hamidi, Hellyeh; Chastney, Megan; Jacquemet, Guillaume; Bruininks, Bart Marlon Herwig; Kaptan, Shreyas; Malerød, Lene; Pedersen, Nina Marie; Brech, Andreas; Matoba, Nobuyuki; Sato, Yuichiro; Vattulainen, Ilpo; Roca-Cusachs, Pere; Perez, Franck; Boncompain, Gaelle; Miserey, Stéphanie; Ivaska, Johanna
The role and regulation of integrins in cell migration and invasion (2025)
- Nature Reviews Molecular Cell Biology
Chastney, Megan R.; Kaivola, Jasmin; Leppänen, Veli-Matti; Ivaska, Johanna
Focal adhesions contain three specialized actin nanoscale layers (2024)
- Nature Communications
Kumari Reena, Ven Katharina, Chastney Megan, Kokate Shrikant B., Peränen Johan, Aaron Jesse, Kogan Konstantin, Almeida-Souza Leonardo, Kremneva Elena, Poincloux Renaud, Chew Teng-Leong, Gunning Peter W., Ivaska Johanna, Lappalainen Pekka
SHANK3 depletion leads to ERK signalling overdose and cell death in KRAS-mutant cancers (2024)
- Nature Communications
Lilja, Johanna; Kaivola, Jasmin; Conway, James R. W.; Vuorio, Joni; Parkkola, Hanna; Roivas, Pekka; Dibus, Michal; Chastney, Megan R.; Varila, Taru; Jacquemet, Guillaume; Peuhu, Emilia; Wang, Emily; Pentikäinen, Ulla; Posada, Itziar Martinez D.; Hamidi, Hellyeh; Najumudeen, Arafath K.; Sansom, Owen J.; Barsukov, Igor L.; Abankwa, Daniel; Vattulainen, Ilpo; Salmi, Marko; Ivaska, Johanna
Integrin adhesion complexes (2021)
- Current Biology
Chastney Megan R., Conway James R. W., Ivaska Johanna