Megan Chastney
 


megan.chastney@utu.fi








Publications

  • Restoring the tumour mechanophenotype of vocal fold cancer reverts its malignant properties  (2026)  
    • Nature Materials
     Kaivola, Jasmin; Punovuori, Karolina; Chastney, Megan R.; Abdo, Hind; Follain, Gautier; Mathieu, Mathilde; Joshi, Omkar; Miroshnikova, Yekaterina A.; Krautgasser, Fabian; Di Franco, Jasmin; Conway, James R. W.; Held, Sofia; Bertillot, Fabien; Hagström, Jaana; Mäkitie, Antti; Irjala, Heikki; Ventelä, Sami; Hamidi, Hellyeh; Scita, Giorgio; Cerbino, Roberto; Wickström, Sara A.; Ivaska, Johanna
    (
    A1 Refereed original research article in a scientific journal)


  • Calponin isoforms define the cell-type-specific organization and dynamics of actomyosin bundles  (2025)  
    • Current Biology
     Kokate, Shrikant B.; Oshin, Afsana T.; Chua, Xiang Le; Chastney, Megan; Biswas, Parijat; Kogan, Konstantin; Tomberg, Teemu; Ivaska, Johanna; Lappalainen, Pekka
    (
    A1 Refereed original research article in a scientific journal)


  • EPLINα controls integrin recycling from Rab21 endosomes to drive breast cancer cell migration  (2025)  
    • Developmental Cell
     Jäntti, Niklas Z.; Moreno-Layseca, Paulina; Chastney, Megan R.; Dibus, Michal; Conway, James R.W.; Leppänen, Veli-Matti; Hamidi, Hellyeh; Eylmann, Kathrin; Oliveira-Ferrer, Leticia; Veltel, Stefan; Ivaska, Johanna
    (
    A1 Refereed original research article in a scientific journal)


  • Integrin β1 activity controls colony morphology during human pluripotent stem cell state transitions  (2025)  
    • Stem Cell Reports
     Taskinen, Maria E.; Pasquier, Nicolas; Stubb, Aki; Joshi, Shreya; Chastney, Megan R.; Rasila, Paula; Vahlman, Sonja; Sokka, Joonas; Lönnberg, Tapio; Mikkola, Lea; Trokovic, Ras; Ivaska, Johanna
    (
    A1 Refereed original research article in a scientific journal)


  • Regulation of cell dynamics by rapid integrin transport through the biosynthetic pathway  (2025)  
    • Journal of Cell Biology
     Lerche, Martina; Mathieu, Mathilde; Hamidi, Hellyeh; Chastney, Megan; Jacquemet, Guillaume; Bruininks, Bart Marlon Herwig; Kaptan, Shreyas; Malerød, Lene; Pedersen, Nina Marie; Brech, Andreas; Matoba, Nobuyuki; Sato, Yuichiro; Vattulainen, Ilpo; Roca-Cusachs, Pere; Perez, Franck; Boncompain, Gaelle; Miserey, Stéphanie; Ivaska, Johanna
    (
    A1 Refereed original research article in a scientific journal)


  • The role and regulation of integrins in cell migration and invasion  (2025)  
    • Nature Reviews Molecular Cell Biology
     Chastney, Megan R.; Kaivola, Jasmin; Leppänen, Veli-Matti; Ivaska, Johanna
    (
    A2 Refereed review article in a scientific journal )


  • Focal adhesions contain three specialized actin nanoscale layers  (2024)  
    • Nature Communications
     Kumari Reena, Ven Katharina, Chastney Megan, Kokate Shrikant B., Peränen Johan, Aaron Jesse, Kogan Konstantin, Almeida-Souza Leonardo, Kremneva Elena, Poincloux Renaud, Chew Teng-Leong, Gunning Peter W., Ivaska Johanna, Lappalainen Pekka
    (
    A1 Refereed original research article in a scientific journal)


  • SHANK3 depletion leads to ERK signalling overdose and cell death in KRAS-mutant cancers  (2024)  
    • Nature Communications
     Lilja, Johanna; Kaivola, Jasmin; Conway, James R. W.; Vuorio, Joni; Parkkola, Hanna; Roivas, Pekka; Dibus, Michal; Chastney, Megan R.; Varila, Taru; Jacquemet, Guillaume; Peuhu, Emilia; Wang, Emily; Pentikäinen, Ulla; Posada, Itziar Martinez D.; Hamidi, Hellyeh; Najumudeen, Arafath K.; Sansom, Owen J.; Barsukov, Igor L.; Abankwa, Daniel; Vattulainen, Ilpo; Salmi, Marko; Ivaska, Johanna
    (
    A1 Refereed original research article in a scientific journal)


  • Integrin adhesion complexes  (2021)  
    • Current Biology
     Chastney Megan R., Conway James R. W., Ivaska Johanna
    (
    B1 Non-refereed article in a scientific journal)



Last updated on 12/07/2023 12:04:16 PM