Jaakko Hentilä - UTU Research Portal

Jaakko Hentilä

Turku PET Centre (Independent units)

jaakko.hentila@utu.fi

Publications

Comparison of Automatic Segmentation and Preprocessing Approaches for Dynamic Total-Body 3D Pet Images with Different Pet Tracers (2025)
- Journal of Imaging Informatics in Medicine
Jaakkola, Maria K.; Rivera Pineda, Marcela Xiomara; Diaz, Rafael; Rantala, Maria; Jalo, Anna; Karpijoki, Henri; Saari, Teemu; Maaniitty, Teemu; Keller, Thomas; Louhi, Heli; Wahlroos, Saara; Haaparanta-Solin, Merja; Solin, Olof; Hentila, Jaakko; Helin, Jatta S.; Nissinen, Tuuli A.; Eskola, Olli; Rajander, Johan; Knuuti, Juhani; Virtanen, Kirsi A.; Hannukainen, Jarna C.; Lopez-Picon, Francisco; Klen, Riku
(A1 Refereed original research article in a scientific journal)
Obesity is associated with increased brain glucose uptake and activity but not neuroinflammation (TSPO availability) in monozygotic twin pairs discordant for BMI—Exercise training reverses increased brain activity (2025)
- Diabetes, Obesity and Metabolism
Hentilä, Jaakko; Tuisku, Jouni; Ojala, Ronja; Sun, Lihua; Lietzén, Martin S.; Virtanen, Heidi; Lautamäki, Riikka; Koskensalo, Kalle; Nummenmaa, Lauri; Löyttyniemi, Eliisa; Helin, Semi; Pietiläinen, Kirsi H.; Kaprio, Jaakko; Lahti, Leo; Malm, Tarja; Rinne, Juha O.; Hannukainen, Jarna C.
(A1 Refereed original research article in a scientific journal)
Bone marrow metabolism is affected by body weight and response to exercise training varies according to anatomical location (2024)
- Diabetes, Obesity and Metabolism
Ojala, R; Hentilä, J; Lietzén, MS; Arponen, M; Heiskanen, MA; Honkala, SM; Virtanen, H; Koskensalo, K; Lautamäki R; Löyttyniemi, E; Parkkola, R; Heinonen, OJ; Malm, T; Lahti, L; Rinne, J; Eskola, O; Rajander, J; Pietiläinen, KH; Kaprio, J; Ivaska, KK; Hannukainen, JC
(A1 Refereed original research article in a scientific journal)
Effects of Obesity and Exercise on Hepatic and Pancreatic Lipid Content and Glucose Metabolism : PET Studies in Twins Discordant for BMI (2024)
- Biomolecules
Lietzén, Martin S.; Mari, Andrea; Ojala, Ronja; Hentilä, Jaakko; Koskensalo, Kalle; Lautamäki, Riikka; Löyttyniemi, Eliisa; Parkkola, Riitta; Saunavaara, Virva; Kirjavainen, Anna K.; Rajander, Johan; Malm, Tarja; Lahti, Leo; Rinne, Juha O.; Pietiläinen, Kirsi H.; Iozzo, Patricia; Hannukainen, Jarna C.
(A1 Refereed original research article in a scientific journal)
Evaluation of bone marrow glucose uptake and adiposity in male rats after diet and exercise interventions (2024)
- Frontiers in Endocrinology
Ojala, Ronja; Widjaja, Nicko; Hentilä, Jaakko; Jalo, Anna; Helin, Jatta S.; Nissinen, Tuuli A.; Jalava, Niki; Eskola, Olli; Rajander, Johan; Löyttyniemi, Eliisa; Ivaska, Kaisa K.; Hannukainen, Jarna C.
(A1 Refereed original research article in a scientific journal)
Mechanisms Leading to Increased Insulin-Stimulated Cerebral Glucose Uptake in Obesity and Insulin Resistance: A High-Fat Diet and Exercise Training Intervention PET Study with Rats (CROSRAT) (2024)
- Journal of Functional Morphology and Kinesiology
Jalo, Anna; Helin, Jatta S.; Hentilä, Jaakko; Nissinen, Tuuli A.; Honkala, Sanna M.; Heiskanen, Marja A.; Löyttyniemi, Eliisa; Malm, Tarja; Hannukainen, Jarna C.
(A1 Refereed original research article in a scientific journal)
Regular Exercise Training Induces More Changes on Intestinal Glucose Uptake from Blood and Microbiota Composition in Leaner Compared to Heavier Individuals in Monozygotic Twins Discordant for BMI (2024)
- Nutrients
Lietzén, Martin S.; Guzzardi, Maria Angela; Ojala, Ronja; Hentilä, Jaakko; Heiskanen, Marja A.; Honkala, Sanna M.; Lautamäki, Riikka; Löyttyniemi, Eliisa; Kirjavainen, Anna K.; Rajander, Johan; Malm, Tarja; Lahti, Leo; Rinne, Juha O.; Pietiläinen, Kirsi H.; Iozzo, Patricia; Hannukainen, Jarna C.
(A1 Refereed original research article in a scientific journal)
Segmentation of Dynamic Total-Body [18F]-FDG PET Images Using Unsupervised Clustering (2023)
- International Journal of Biomedical Imaging
Jaakkola Maria K., Rantala Maria, Jalo Anna, Saari Teemu, Hentilä Jaakko, Helin Jatta S., Nissinen Tuuli A., Eskola Olli, Rajander Johan, Virtanen Kirsi A., Hannukainen Jarna C., López-Picón Francisco, Klén Riku
(A1 Refereed original research article in a scientific journal)
Systemic cross-talk between brain, gut, and peripheral tissues in glucose homeostasis: effects of exercise training (CROSSYS). Exercise training intervention in monozygotic twins discordant for body weight (2021)
- BMC sports science, medicine and rehabilitation
Heiskanen Marja A, Honkala Sanna M, Hentilä Jaakko, Ojala Ronja, Lautamäki Riikka, Koskensalo Kalle, Lietzen Martin S, Saunavaara Virva, Saunavaara Jani, Helmiö Mika, Löyttyniemi Eliisa, Nummenmaa Lauri, Collado Maria C, Malm Tarja, Lahti Leo, Pietiläinen Kirsi H, Kaprio Jaakko, Rinne Juha O, Hannukainen Jarna C
(A1 Refereed original research article in a scientific journal)
Muscle NAD+ depletion and Serpina3n as molecular determinants of murine cancer cachexia—the effects of blocking myostatin and activins (2020)
- Molecular Metabolism
Hulmi JJ, Penna F, Pöllänen N, Nissinen TA, Hentilä J, Euro L, Lautaoja JH, Ballarò R, Soliymani R, Baumann M, Ritvos O, Pirinen E, Lalowski M
(A1 Refereed original research article in a scientific journal)
Sprint and Strength Training Modulates Autophagy and Proteostasis in Aging Sprinters (2020)
- Medicine and Science in Sports and Exercise
HentilÄ J, Hulmi JJ, Laakkonen EK, Ahtiainen JP, Suominen H, Korhonen MT
(A1 Refereed original research article in a scientific journal)
Blocking activin receptor ligands is not sufficient to rescue cancer-associated gut microbiota - a role for gut microbial flagellin in colorectal cancer and cachexia? (2019)
- Cancers
Satu Pekkala, Anniina Keskitalo, Emilia Kettunen, Sanna Lensu, Noora Nykänen, Teijo Kuopio, Olli Ritvos, Jaakko Hentilä, Tuuli A. Nissinen, Juha J. Hulmi
(A1 Refereed original research article in a scientific journal)
Muscle and serum metabolomes are dysregulated in colon-26 tumor-bearing mice despite amelioration of cachexia with activin receptor type 2B ligand blockade (2019)
- American Journal of Physiology : Endocrinology and Metabolism
Lautaoja JH, Lalowski M, Nissinen TA, Hentilä J, Shi Y, Ritvos O, Cheng S, Hulmi JJ
(A1 Refereed original research article in a scientific journal)