Pekka Postila
University Lecturer; Associate Professor / Docent; Ph.D.
pekka.postila@utu.fi Office: C642 ORCID identifier: https://orcid.org/0000-0002-2947-7991 |
Areas of expertise
Computer-aided drug discovery; virtual screening; molecular dynamics simulations; molecular modelling; structural bioinformatics
Computer-aided drug discovery; virtual screening; molecular dynamics simulations; molecular modelling; structural bioinformatics
Publications
- Female mice with HSD17B1 inactivation show mild hyperandrogenism without notable impact on reproductive function or bone (2026)
- Endocrinology
(A1 Refereed original research article in a scientific journal) - Designing fluorescent estrogen mimetic 7-hydroxycoumarin probe substrates for human sulfotransferase enzymes (2025)
- European Journal of Pharmaceutical Sciences
(A1 Refereed original research article in a scientific journal) - Atomistic simulations reveal impacts of missense mutations on the structure and function of SynGAP1 (2024)
- Briefings in Bioinformatics
(A1 Refereed original research article in a scientific journal) - Building shape-focused pharmacophore models for effective docking screening (2024)
- Journal of cheminformatics
(A1 Refereed original research article in a scientific journal) - Virtual Screening Strategy to Identify Retinoic Acid-Related Orphan Receptor γt Modulators (2023)
- Molecules
(A1 Refereed original research article in a scientific journal) - Examining the Effect of Charged Lipids on Mitochondrial Outer Membrane Dynamics Using Atomistic Simulations (2022)
- Biomolecules
(A1 Refereed original research article in a scientific journal) - Ligand-Enhanced Negative Images Optimized for Docking Rescoring (2022)
- International Journal of Molecular Sciences
(A1 Refereed original research article in a scientific journal) - Optimization of Cavity-Based Negative Images to Boost Docking Enrichment in Virtual Screening (2022)
- Journal of Chemical Information and Modeling
(A1 Refereed original research article in a scientific journal) - Negative Image-Based Rescoring: Using Cavity Information to Improve Docking Screening (2021) Protein-Ligand Interactions and Drug Design Pentikäinen Olli T., Postila Pekka A.
(A3 Refereed book chapter or chapter in a compilation book) - Negative Image-Based Screening: Rigid Docking Using Cavity Information (2021) Protein-Ligand Interactions and Drug Design Postila Pekka A., Kurkinen Sami T., Pentikäinen Olli T.
(A3 Refereed book chapter or chapter in a compilation book)



