I did a PhD in life science in the lab. of Dr. Jacky Goetz (Strasbourg). I studied the role of blood flow forces on arrest, adhesion and extravasation of circulating breast/mammary cells, using multiple imaging modalities, mostly applied to microfluidics and zebrafish embryos. I described endothelial remodeling around arrested tumor cells as an extravasation mechanism of cancer cells (Follain et al. Dev cell 2018). Our works demonstrated that not only size exclusion but also shear forces are biophysic parameters driving the metastatic spreading (Follain et al. NRC 2020).
I moved to Turku in 2020 as a shared postdoc between the Cell Adhesion and Cancer lab of Prof. J. Ivaska and the lab of Dr. G. Jacquemet focusing on cellular protrusion and Cell Migration. I used similar models to study the metastatic cascade of Pancreatic Ductal AdenoCarcinoma.

Main focus : Studying the metastatic spreading of Pancreatic Ductal AdenoCarcinoma.