Vilhelmiina Parikka
MD, PhD
PET-keskus vilpar@utu.fi ORCID identifier: https://orcid.org/0000-0002-9281-8154 |
Neonatology; hypoxic-ischemic brain injury; inflammation; PET; biomarkers
Vilhelmiina Parikka, MD, PhD has a clinical position at Turku University Hospital, where she works in the neonatal intensive care unit as an attending neonatologist. After her postdoctoral period in Boston Children’s Hospital / Harvard Medical School (2017–2019), she has established a research group focusing on the investigation of neonatal hypoxic-ischemic encephalopathy. Parikka’s research group works with both preclinical brain injury models and clinical study setups.
The main interest of Vilhelmiina Parikka’s research group is in pathophysiological mechanisms and treatment options for neonatal hypoxic-ischemic injury. The research project aims to provide deeper understanding of the pathological processes behind the brain injury, to identify tools for the early recognition of the injury and to develop new clinically relevant strategies for the treatment of this group of vulnerable infants. The research group has a special interest in the role of inflammation and endothelial injury in the pathophysiological process of the brain injury. The role of PET imaging scans as an early marker for metabolic changes and inflammation in a preclinical model of neonatal hypoxic-ischemic encephalopathy is also actively studied.
- Evaluation of PET imaging as a tool for detecting neonatal hypoxic-ischemic encephalopathy in a preclinical animal model (2024)
- Experimental Neurology
(A1 Refereed original research article in a scientific journal) - Overlap between EEC and AEC syndrome and immunodeficiency in a preterm infant with a TP63 variant (2023)
- European Journal of Medical Genetics
(A1 Refereed original research article in a scientific journal) - Small animal PET with spontaneous inhalation of 15O-labelled oxygen gases: Longitudinal assessment of cerebral oxygen metabolism in a rat model of neonatal hypoxic-ischaemic encephalopathy (2023)
- Journal of Cerebral Blood Flow and Metabolism
(A1 Refereed original research article in a scientific journal) - Implementation of neurally adjusted ventilatory assist and high flow nasal cannula in very preterm infants in a tertiary level NICU (2022)
- Pediatric Pulmonology
(A1 Refereed original research article in a scientific journal) - NIV-NAVA versus NCPAP immediately after birth in premature infants: A randomized controlled trial (2022)
- Respiratory Physiology and Neurobiology
(A1 Refereed original research article in a scientific journal) - Parent-infant skin-to-skin contact reduces the electrical activity of the diaphragm and stabilizes respiratory function in preterm infants (2022)
- Pediatric Research
(A1 Refereed original research article in a scientific journal) - Backup ventilation during neurally adjusted ventilatory assist in preterm infants (2021)
- Pediatric Pulmonology
(A1 Refereed original research article in a scientific journal) - Extremely viscous stool in a newborn leading to an early diagnosis of a life-long disease (2021)
- BMJ case reports
(B1 Non-refereed article in a scientific journal) - Neurally adjusted ventilatory assist in ventilated very preterm infants: A crossover study (2021)
- Pediatric Pulmonology
(A1 Refereed original research article in a scientific journal) - Uncommon cause of respiratory distress-late-presenting congenital diaphragmatic hernia (2021)
- BMJ case reports
(B1 Non-refereed article in a scientific journal) - Rapid respiratory transition at birth as evaluated by electrical activity of the diaphragm in very preterm infants supported by nasal CPAP (2018)
- Respiratory Physiology and Neurobiology
(A1 Refereed original research article in a scientific journal) - Estrogen reduces the depth of resorption pits by disturbing the organic bone matrix degradation activity of mature osteoclasts (2001)
- Endocrinology
(A1 Refereed original research article in a scientific journal)