Saara Laine - UTU Research Portal

Saara Laine

- Coordinator,
Faculty of Medicine (University of Turku)

saalaiy@utu.fi

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Effects of reducing sedentary behavior on liver insulin sensitivity, liver fat content, and liver enzyme levels : a six-month randomized controlled trial (2025)
- American Journal of Physiology : Endocrinology and Metabolism
Laine, Saara; Sjöros, Tanja; Garthwaite, Taru; Honka, Miikka-Juhani; Löyttyniemi, Eliisa; Norha, Jooa; Eskola, Olli; Koivumäki, Mikko; Vähä-Ypyä, Henri; Sievänen, Harri; Vasankari, Tommi; Hirvonen, Jussi; Laitinen, Kirsi; Houttu, Noora; Kalliokoski, Kari K.; Saunavaara, Virva; Knuuti, Juhani; Heinonen, Ilkka H. A.
Effects of Reducing Sedentary Behaviour on Cardiac Structure and Function at Rest and During Exercise: A 6-Month Randomized Controlled Trial (2025)
- CJC Open
Norha, Jooa; Saarenhovi, Maria; Kallio, Petri; Sjöros, Tanja; Garthwaite, Taru; Laine, Saara; Houttu, Noora; Laitinen, Kirsi; Vähä-Ypyä, Henri; Sievänen, Harri; Löyttyniemi, Eliisa; Vasankari, Tommi; Knuuti, Juhani; Kalliokoski, Kari K.; Heinonen, Ilkka H. A.
Effects of reducing sedentary behaviour on renal glucose uptake during insulin stimulation: A post‐hoc analysis of a 6‐month randomized controlled trial (2025)
- Diabetes, Obesity and Metabolism
Rebelos, Eleni; Dadson, Prince; Sjöros, Tanja; Laine, Saara; Norha, Jooa; Garthwaite, Taru; Löyttyniemi, Eliisa; Eskola, Olli; Koivumäki, Mikko; Vähä‐Ypyä, Henri; Sievänen, Harri; Vasankari, Tommi; Hirvonen, Jussi; Laitinen, Kirsi; Houttu, Noora; Kalliokoski, Kari K.; Knuuti, Juhani; Ferrannini, Ele; Mari, Andrea; Heinonen, Ilkka
Lifestyle factors, liver insulin sensitivity, liver fat, and liver enzymes in adults with metabolic syndrome (2025) Laine, Saara
Mildly elevated liver lipid content is characterised by reduced insulin sensitivity (2025)
- JHEP Reports
Tuomola, Nelli; Rebelos, Eleni; Latva-Rasku, Aino; Bucci, Marco; Immonen, Heidi; Saunavaara, Virva; Laine, Saara; Sjöros, Tanja; Garthwaite, Taru; Raiko, Juho R.H.; Fernandes Silva, Lilian; Virtanen, Kirsi A.; Hannukainen, Jarna C.; Ala-Korpela, Mika; Kalliokoski, Kari K.; Heinonen, Ilkka H.A.; Nuutila, Pirjo; Honka, Miikka-Juhani
Secondary analysis of a randomised controlled trial on reducing sedentary behaviour and its effects on quality of life and wellbeing (2025)
- Scientific Reports
Norha, Jooa; Sjöros, Tanja; Garthwaite, Taru; Laine, Saara; Laitinen, Kirsi; Houttu, Noora; Vähä-Ypyä, Henri; Sievänen, Harri; Löyttyniemi, Eliisa; Vasankari, Tommi; Knuuti, Juhani; Kalliokoski, Kari K.; Heinonen, Ilkka H. A.
Successfully Reducing Sitting Time Can Improve Metabolic Flexibility (2025)
- Scandinavian Journal of Medicine and Science in Sports
Garthwaite, Taru; Sjöros, Tanja; Laine, Saara; Koivumäki, Mikko; Vähä‐Ypyä, Henri; Norha, Jooa; Kallio, Petri; Saarenhovi, Maria; Löyttyniemi, Eliisa; Sievänen, Harri; Houttu, Noora; Laitinen, Kirsi; Kalliokoski, Kari K.; Vasankari, Tommi; Knuuti, Juhani; Heinonen, Ilkka
Daily standing time, dietary fiber, and intake of unsaturated fatty acids are beneficially associated with hepatic insulin sensitivity in adults with metabolic syndrome (2024)
- Frontiers in Endocrinology
Laine, Saara; Sjöros, Tanja; Garthwaite, Taru; Honka, Miikka-Juhani; Löyttyniemi, Eliisa; Eskola, Olli; Saarenhovi, Maria; Kallio, Petri; Koivumäki, Mikko; Vähä-Ypyä, Henri; Sievänen, Harri; Vasankari, Tommi; Hirvonen, Jussi; Laitinen, Kirsi; Houttu, Noora; Kalliokoski, Kari; Saunavaara, Virva; Knuuti, Juhani; Heinonen, Ilkka H.A.
Effects of reduced sedentary time on resting, exercise and post-exercise blood pressure in inactive adults with metabolic syndrome – a six-month exploratory RCT (2024)
- Journal of Human Hypertension
Norha Jooa, Sjöros Tanja, Garthwaite Taru, Laine Saara, Saarenhovi Maria, Kallio Petri, Laitinen Kirsi, Houttu Noora, Vähä-Ypyä Henri, Sievänen Harri, Löyttyniemi Eliisa, Vasankari Tommi, Knuuti Juhani, Kalliokoski Kari K., Heinonen Ilkka H. A.
Effects of reducing sedentary behaviour on back pain, paraspinal muscle insulin sensitivity and muscle fat fraction and their associations: a secondary analysis of a 6-month randomised controlled trial (2024)
- BMJ Open
Norha, Jooa; Sjöros, Tanja: Garthwaite, Taru; Laine, Saara; Verho, Tiina; Saunavaara, Virva; Laitinen, Kirsi; Houttu, Noora; Hirvonen, Jussi; Vähä-Ypyä, Henri; Sievänen, Harri; Löyttyniemi, Eliisa; Vasankari, Tommi; Kalliokoski, Kari; Heinonen, Ilkka
Sedentary behavior reduction and blood lipids in adults with metabolic syndrome: a 6-month randomized controlled trial (2024)
- Scientific Reports
Ylinen, Venla P.; Sjöros, Tanja; Laine, Saara; Garthwaite, Taru; Norh,a Jooa; Vähä-Ypyä, Henri; Löyttyniemi, Eliisa; Houttu, Noora; Laitinen, Kirsi; Kalliokoski, Kari K.; Sievänen, Harri; Vasankari, Tommi; Knuut,i Juhani; Heinonen, Ilkka HA
Sedentary time associates detrimentally and physical activity beneficially with metabolic flexibility in adults with metabolic syndrome (2024)
- American Journal of Physiology : Endocrinology and Metabolism
Garthwaite Taru, Sjöros Tanja, Laine Saara, Koivumäki Mikko, Vähä-Ypyä Henri, Verho Tiina, Norha Jooa, Kallio Petri, Saarenhovi Maria, Löyttyniemi Eliisa, Sievänen Harri, Houttu Noora, Laitinen Kirsi, Kalliokoski Kari K., Vasankari Tommi, Knuuti Juhani, Heinonen Ilkka
Tiredness after work associates with less leisure-time physical activity (2024)
- Scientific Reports
Sjöros Tanja, Norha Jooa, Johansson Riitta, Laine Saara, Garthwaite Taru, Vähä-Ypyä Henri, Löyttyniemi Eliisa, Kalliokoski Kari K., Sievänen Harri, Vasankari Tommi, Knuuti Juhani, Heinonen Ilkka H. A.
Associations of sedentary time, physical activity, and fitness with muscle glucose uptake in adults with metabolic syndrome (2023)
- Scandinavian Journal of Medicine and Science in Sports
Garthwaite Taru, Sjöros Tanja, Laine Saara, Koivumäki Mikko, Vähä-Ypyä Henri, Eskola Olli, Rajander Johan, Kallio Petri, Saarenhovi Maria, Löyttyniemi Eliisa, Sievänen Harri, Houttu Noora, Laitinen Kirsi, Kalliokoski Kari, Vasankari Tommi, Knuuti Juhani, Heinonen Ilkka
Effects of reducing sedentary behavior on cardiorespiratory fitness in adults with metabolic syndrome: A 6-month RCT (2023)
- Scandinavian Journal of Medicine and Science in Sports
Norha Jooa, Sjöros Tanja, Garthwaite Taru, Laine Saara, Saarenhovi Maria, Kallio Petri, Laitinen Kirsi, Houttu Noora, Vähä-Ypyä Henri, Sievänen Harri, Löyttyniemi Eliisa, Vasankari Tommi, Knuuti Juhani, Kalliokoski Kari K., Heinonen Ilkka H.A.
Reducing Sedentary Time and Whole-Body Insulin Sensitivity in Metabolic Syndrome - A 6-Month Randomized Controlled Trial (2023)
- Medicine and Science in Sports and Exercise
Sjöros Tanja, Laine Saara, Garthwaite Taru, Vähä-Ypyä Henri, Löyttyniemi Eliisa, Koivumäki Mikko, Houttu Noora, Laitinen Kirsi, Kalliokoski Kari K., Sievänen Harri, Vasankari Tomi, Knuuti Juhani, Heinonen Ilkka H.A.
The effects of a 6-month intervention aimed to reduce sedentary time on skeletal muscle insulin sensitivity: a randomized controlled trial (2023)
- American Journal of Physiology : Endocrinology and Metabolism
Sjöros Tanja, Laine Saara, Garthwaite Taru, Vähä-Ypyä Henri, Koivumäki Mikko, Eskola Olli, Löyttyniemi Eliisa, Houttu Noora, Laitinen Kirsi, Kalliokoski Kari K., Sievänen Harri, Vasankari Tommi, Knuuti Juhani, Heinonen Ilkka H.A.
The Effects Of Reducing Sedentary Behavior On Cardiorespiratory Fitness: A Six-month Randomized Controlled Trial (2023)
- Medicine and Science in Sports and Exercise
Norha Jooa, Sjöros Tanja, Garthwaite Taru, Laine Saara, Saarenhovi Maria, Kallio Petri, Laitinen Kirsi, Houttu Noora, Vähä-Ypyä Henri, Sievänen Harri, Löyttyniemi Eliisa, Vasankari Tommi, Knuuti Juhani, Kalliokoski Kari K., Heinonen Ilkka H.A.
Association between cardiorespiratory fitness and metabolic health in overweight and obese adults (2022)
- Journal of Sports Medicine and Physical Fitness
Haapala Eero A, Sjöros Tanja, Laine Saara, Garthwaite Taru, Kallio Petri, Saarenhovi Maria, Vähä-Ypyä Henri, Löyttyniemi Eliisa, Sievänen Harri, Houttu Noora, Laitinen Kirsi, Kalliokoski Kari, Knuuti Juhani, Vasankari Tommi, Heinonen Ilkka H
Corrigendum to “Standing is associated with insulin sensitivity in adults with metabolic syndrome. Journal of Science and Medicine in Sport 24 (2021) 1255–1260” (Journal of Science and Medicine in Sport (2021) 24(12) (1255–1260), (S1440244021002048), (10.1016/j.jsams.2021.08.009)) (2022)
- Journal of Science and Medicine in Sport
Garthwaite Taru, Sjöros Tanja, Koivumäki Mikko, Laine Saara, Vähä-Ypyä Henri, Saarenhovi Maria, Kallio Petri, Löyttyniemi Eliisa, Sievänen Harri, Houttu Noora, Laitinen Kirsi, Kalliokoski Kari, Vasankari Tommi, Knuuti Juhani, Heinonen Ilkka