Heli Tirkkonen - UTU Research Portal

Heli Tirkkonen

- Doctoral Researcher,
Department of Life Technologies (Faculty of Technology)
- Doctoral Researcher,
Biochemistry (Department of Life Technologies)

heli.m.tirkkonen@utu.fi

streptomyces; natural products chemistry; microbial interactions

I study microbial interactions between Streptomyces and other microbes. Streptomyces utilize enzymes and natural products in their warfare against other microbes. By studying these interactions, we can uncover new antimicrobial compounds.

Engineering BioBricks for Deoxysugar Biosynthesis and Generation of New Tetracenomycins (2023)
- ACS Omega
Tirkkonen Heli, Brown Katelyn V, Niemczura Magdalena, Faudemer Zélie, Brown Cortney, Ponomareva Larissa V , Helmy Yorsta A, Thorson Jon S, Nybo S Eric, Metsä-Ketelä Mikko, Shaaban Khaled A
Evolution-inspired engineering of anthracycline methyltransferases (2023)
- PNAS nexus
Dinis Pedro, Tirkkonen Heli, Nji Wandi Benjamin N, Siitonen Vilja, Niemi Jarmo, Grocholski Thadée, Metsä-Ketelä Mikko
Evolutionary Trajectories for the Functional Diversification of Anthracycline Methyltransferases (2019)
- ACS Chemical Biology
Grocholski T., Yamada K., Sinkkonen J., Tirkkonen H., Niemi J., Metsä-Ketelä M.