Karolina Losenkova Mingeaud

MediCity (Faculty of Medicine)

karolina.losenkova@utu.fi

+358 29 450 4377

+358 50 514 2809

Tykistökatu 6

Turku

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Fluorine‐18‐Labeled Nucleotide Analogs Targeting Ecto‐5'‐Nucleotidase (CD73) for Positron Emission Tomography Imaging of Solid Tumors (2026)
- Angewandte Chemie International Edition
Dobelmann, Clemens; Schmies, Constanze C.; Rolshoven, Georg Wilhelm; Scortichini, Mirko; Wagner, Stefan; Isaak, Andreas; Idris, Riham M.; Dabel, Jennifer; Grey, Lucie; Losenkova, Karolina; Moschutz, Susanne; Al Hroub, Haneen; Keim, Antje; Hoppner, Sandra; Sandholm, Jouko; Bostrom, Pia; Hollmen, Maija; Strater, Norbert; Hermann, Sven; Yegutkin, Gennady G.; Jacobson, Kenneth A.; Schelhaas, Sonja; Muller, Christa E.; Junker, Anna
Adenosine metabolism in cancer: unveiling new therapeutic opportunities (2025) Losenkova Mingeaud, Karolina
CD73 controls ocular adenosine levels and protects retina from light-induced phototoxicity (2022)
- Cellular and Molecular Life Sciences
Losenkova Karolina, Takeda Akira, Ragauskas Symantas, Cerrada-Gimenez Marc, Vähätupa Maria, Kaja Simon, Paul Marius L., Schmies Constanze C., Rolshoven Georg, Müller Christa E., Sandholm Jouko, Jalkanen Sirpa, Kalesnykas Giedrius, Yegutkin Gennady G.
Structure-Activity Relationship of 3-Methylcytidine-5 '-alpha,beta-methylenediphosphates as CD73 Inhibitors (2022)
- Journal of Medicinal Chemistry
Scortichini Mirko, Idris Riham Mohammed, Moschutz Susanne, Keim Antje, Salmaso Veronica, Dobelmann Clemens, Oliva Paola, Losenkova Karolina, Irjala Heikki, Vaittinen Samuli, Sandholm Jouko, Yegutkin Gennady G, Sträter Norbert, Junker Anna, Müller Christa E, Jacobson Kenneth A
Structure activity relationship of 3-methylcytidine-5'-α,β-methylenediphosphates as CD73 inhibitors (2022)
- FASEB Journal
EB 2022 Jacobson Kenneth A., Scortichini Mirko, Idris Riham M., Moschütz Suzanne, Keim Antje, Salmaso Veronica A., Dobelmann Clemens, Oliva Paola A., Losenkova Karolina, Irjala Heikki, Vaittinen Samuli, Sandholm Jouko, Yegutkin Gennady G., Sträter Norbert, Junker Anna, Müller Christa E.
Compartmentalization of adenosine metabolism in cancer cells and its modulation during acute hypoxia (2020)
- Journal of Cell Science
Losenkova K, Zuccarini M, Karikoski M, Laurila J, Boison D, Jalkanen S, Yegutkin GG
First person - Karolina Losenkova (2020)
- Journal of Cell Science
Losenkova Karolina
Fluorescent Probes for Ecto-5 '-nucleotidase (CD73) (2020)
- ACS Medicinal Chemistry Letters
Schmies CC, Rolshoven G, Idris RM, Losenkova K, Renn C, Schakel L, Al-Hroub H, Wang YL, Garofano F, Schmidt-Wolf IGH, Zimmermann H, Yegutkin GG, Muller CE
Fully human anti-CD39 antibody potently inhibits ATPase activity in cancer cells via uncompetitive allosteric mechanism (2020)
- mAbs
Spatola BN, Lerner AG, Wong C, dela Cruz T, Welch M, Fung WC, Kovalenko M, Losenkova K, Yegutkin GG, Beers C, Corbin J, Soros VB
Histochemical approach for simultaneous detection of ectonucleotidase and alkaline phosphatase activities in tissues (2020) Purinergic Signaling Karolina Losenkova, Marius Paul, Heikki Irjala, Sirpa Jalkanen, Gennady G. Yegutkin