Santosh Lamichhane
Academy Research fellow
santosh.lamichhane@utu.fi |
Lipidomics/Metabolomics
Gut microbial metabolism
Multivariate data analysis
Reverse Metabolomics
Molecular networking
Santosh Lamichhane is a Research Council of Finland Academy Research Fellow. He holds the title of Docent, equivalent to Associate Professor, in Metabolomics at the Department of Life Technologies, University of Turku.
As part of his research fellowship, Lamichhane will investigate the relationship between gut microbiota, lipids, and their clinical effects in early childhood.
Lamichhane was a Visiting Researcher at The Dorrestein Lab, University of California, San Diego, where he gained expertise in reverse and repository-scale metabolomics to better understand microbial chemistry and its influence on human metabolism.
Lamichhane's research interest lies in the interface of human health, diet and gut microbial activity. He wants to connect these dots (health, diet, microbes) by profiling small molecules (termed as metabolites), which circulates in our body. To be very specific Lamichhanes core interest are reflected by following keywords:
- Metabolomics-Metabolites-Small molecules
- Human Nutrition and health
- Pre and Probiotics / Gut Microbiome
- Human intervention study
Relating to Lamichhane's experience, he has spent approximately a decade profiling small molecules in relation to human heath and (or) gut metabolome. He is open to collaborations relating to gut, health, metabolites and microbiome.
Metabolomics lecture in Systems biology (SYS21012), Modern biotechnologies and bioinformatics course (BIOT1524), Bioanalytical Techniques (CHEMI6429) at University of Turku.
- A guide to reverse metabolomics—a framework for big data discovery strategy (2025)
- Nature Protocols
(A2 Refereed review article in a scientific journal ) - Comparative Metabolomics and Microbiome Analysis of Ethanol versus OMNImet/gene•GUT Fecal Stabilization (2024)
- Analytical Chemistry
(A1 Refereed original research article in a scientific journal) - IL-22 resolves MASLD via enterocyte STAT3 restoration of diet-perturbed intestinal homeostasis (2024)
- Cell Metabolism
(A1 Refereed original research article in a scientific journal) - Infant gut microbiota and negative and fear reactivity (2024)
- Development and Psychopathology
(A1 Refereed original research article in a scientific journal) - Multiplatform metabolomic interlaboratory study of a whole human stool candidate reference material from omnivore and vegan donors (2024)
- Metabolomics
(A1 Refereed original research article in a scientific journal) - Serum proteomics of mother-infant dyads carrying HLA-conferred type 1 diabetes risk (2024)
- iScience
(A1 Refereed original research article in a scientific journal) - Changes in lipids and inflammation in adults with super-refractory status epilepticus on a ketogenic diet (2023)
- Frontiers in Molecular Biosciences
(A1 Refereed original research article in a scientific journal) - Circulating metabolic signatures of rapid and slow progression to type 1 diabetes in islet autoantibody-positive children (2023)
- Frontiers in Endocrinology
(A1 Refereed original research article in a scientific journal) - Classification of Common Food Lipid Sources Regarding Healthiness Using Advanced Lipidomics: A Four-Arm Crossover Study (2023)
- International Journal of Molecular Sciences
(A1 Refereed original research article in a scientific journal) - Deep learning facilitates multi-data type analysis and predictive biomarker discovery in cancer precision medicine (2023)
- Computational and Structural Biotechnology Journal
(A2 Refereed review article in a scientific journal ) - Dynamics of the Lipidome in a Colon Simulator (2023)
- Metabolites
(A1 Refereed original research article in a scientific journal) - Impact of exposure to per- and polyfluoroalkyl substances on fecal microbiota composition in mother-infant dyads (2023)
- Environment International
(A1 Refereed original research article in a scientific journal) - Recent advances towards mass spectrometry-based clinical lipidomics (2023)
- Current Opinion in Chemical Biology
(A2 Refereed review article in a scientific journal ) - Dysregulation of secondary bile acid metabolism precedes islet autoimmunity and type 1 diabetes (2022)
- Cell Reports Medicine
(A1 Refereed original research article in a scientific journal) - Impact of Extensively Hydrolyzed Infant Formula on Circulating Lipids During Early Life (2022)
- Frontiers in Nutrition
(A1 Refereed original research article in a scientific journal) - Association Between Circulating Lipids and Future Weight Gain in Individuals With an At-Risk Mental State and in First-Episode Psychosis (2021)
- Schizophrenia Bulletin
(A1 Refereed original research article in a scientific journal) - Deep learning meets metabolomics: a methodological perspective (2021)
- Briefings in Bioinformatics
(A2 Refereed review article in a scientific journal ) - Exposure to per- and polyfluoroalkyl substances associates with an altered lipid composition of breast milk (2021)
- Environment International
(A1 Refereed original research article in a scientific journal) - Linking Gut Microbiome and Lipid Metabolism: Moving beyond Associations (2021)
- Metabolites
(A2 Refereed review article in a scientific journal ) - Systems biology approaches to study lipidomes in health and disease (2021)
- Biochimica et Biophysica Acta Molecular and Cell Biology of Lipids
(A2 Refereed review article in a scientific journal )