Lea Sistonen - UTU Research Portal

Lea Sistonen

Turku Bioscience Centre (Independent units)

lea.sistonen@bioscience.fi

Publications

1 of 2

Heat shock factor 2 regulates oncogenic gamma-herpesvirus gene expression by remodeling the chromatin at the ORF50 and BZLF1 promoter (2025)
- PLoS Pathogens
Cutrone, Lorenza; Djupenström, Hedvig; Peltonen, Jasmin; Martinez, Klimova Elena; Corso, Simona; Giordano, Silvia; Sistonen, Lea; Gramolelli, Silvia
(A1 Refereed original research article in a scientific journal)
Nuclear talin-1 provides a bridge between cell adhesion and gene expression (2025)
- iScience
Da Silva, Alejandro J.; Hästbacka, Hendrik S. E.; Puustinen, Mikael C.; Pessa, Jenny C.; Luoto, Jens C.; Sundström, Erika; Goult, Benjamin T.; Jacquemet, Guillaume; Henriksson, Eva; Sistonen, Lea
(A1 Refereed original research article in a scientific journal)
Comprehensive analysis of human tissues reveals unique expression and localization patterns of HSF1 and HSF2 (2024)
- Cell Stress and Chaperones
Joutsen Jenny, Pessa Jenny C., Jokelainen Otto, Sironen Reijo, Hartikainen Jaana M., Sistonen Lea
(A1 Refereed original research article in a scientific journal)
Proteomic profiling identifies a direct interaction between heat shock transcription factor 2 and the focal adhesion adapter talin‐1 (2024)
- FEBS Journal
Da Silva, Alejandro J.; Hästbacka, Hendrik S. E.; Luoto, Jens C.; Gough, Rosemarie E.; Coelho-Rato, Leila S.; Laitala, Leena M.; Goult, Benjamin T.; Imanishi, Susumu Y.; Sistonen, Lea; Henriksson, Eva
(A1 Refereed original research article in a scientific journal)
Stress Biology : Complexity and Multifariousness in Health and Disease (2024)
- Cell Stress and Chaperones
Mayer Matthias P., Blair Laura, Blatch Gregory L., Borges Thiago J., Chadli Ahmed, Chiosis Gabriela, de Thonel Aurélie, Dinkova-Kostova Albena, Ecroyd Heath, Edkins Adrienne L., Eguchi Takanori, Fleshner Monika, Foley Kevin P., Fragkostefanakis Sotirios, Gestwicki Jason, Goloubinoff Pierre, Heritz Jennifer A., Heske Christine M., Hibshman Jonathan D., Joutsen Jenny, Li Wei, Lynes Michael, Mendillo Marc L., Mivechi Nahid, Mokoena Fortunate, Okusha Yuka, Prahlad Veena, Repasky Elizabeth, Sannino Sara, Scalia Federica, Shalgi Reut, Sistonen Lea, Sontag Emily, van Oosten-Hawle Patricija, Vihervaara Anniina, Wickramaratne Anushka, Wang Shawn Xiang Yang, Zininga Tawanda
(A1 Refereed original research article in a scientific journal)
Transcriptional reprogramming at the intersection of the heat shock response and proteostasis (2024)
- Molecular Cell
Pessa Jenny C, Joutsen Jenny, Sistonen Lea
(A2 Refereed review article in a scientific journal )
Author Correction: CBP-HSF2 structural and functional interplay in Rubinstein-Taybi neurodevelopmental disorder (Nature Communications, (2022), 13, 1, (7002), 10.1038/s41467-022-34476-2) (2023)
- Nature Communications
de Thonel A., Ahlskog J.K., Daupin K., Dubreuil V., Berthelet J., Chaput C., Pires G., Leonetti C., Abane R., Barris L.C., Leray I., Aalto A.L., Naceri S., Cordonnier M., Benasolo C., Sanial M., Duchateau A., Vihervaara A., Puustinen M.C., Miozzo F., Fergelot P., Lebigot É., Verloes A., Gressens P., Lacombe D., Gobbo J., Garrido C., Westerheide S.D., David L., Petitjean M., Taboureau O., Rodrigues-Lima F., Passemard S., Sabéran-Djoneidi D., Nguyen L., Lancaster M., Sistonen L., Mezger V.
(Other publication)
Cancer cell invasion alters the protein profile of extracellular vesicles (2023)
- Journal of Extracellular Biology
Luoto, Jens C.; Coelho-Rato, Leila S.; Jungarå, Cecilia; Bengs, Sara H.; Roininen, Jannica; Eriksson, John E.; Sistonen, Lea; Henriksson, Eva
(A1 Refereed original research article in a scientific journal)
Second Virtual International Symposium on Cellular and Organismal Stress Responses, September 8-9, 2022 (2023)
- Cell Stress and Chaperones
van Oosten-Hawle Patricija, Backe Sarah J, Ben-Zvi Anat, Bourboulia Dimitra, Brancaccio Mara, Brodsky Jeff, Clark Melody, Colombo Giorgio, Cox Marc B, de los Rios Paolo, Echtenkamp Frank, Edkins Adrienne, Freeman Brian, Goloubinoff Pierre, Houry Walid, Johnson Jill, LaPointe Paul, Li Wei, Mezger Valerie, Neckers Len, Nillegoda Nadinath B, Prahlad Veena, Reitzel Adam, Scherz-Shouval Ruth, Sistonen Lea, Tsai Francis TF, Woodford Mark R, Mollapour Mehdi, Truman Andrew W
(B1 Non-refereed article in a scientific journal)
CBP-HSF2 structural and functional interplay in Rubinstein-Taybi neurodevelopmental disorder (2022)
- Nature Communications
de Thonel Aurélie, Ahlskog Johanna K., Daupin Kevin, Dubreuil Véronique, Berthelet Jérémy, Chaput Carole, Pires Geoffrey, Leonetti Camille, Abane Ryma, Barris Lluís Cordón, Leray Isabelle, Aalto Anna L., Naceri Sarah, Cordonnier Marine, Benasolo Carène, Sanial Matthieu, Duchateau Agathe, Vihervaara Anniina, Puustinen Mikael C., Miozzo Federico, Fergelot Patricia, Lebigot Élise, Verloes Alain, Gressens Pierre, Lacombe Didier, Gobbo Jessica, Garrido Carmen, Westerheide Sandy D., David Laurent, Petitjean Michel, Taboureau Olivier, Rodrigues-Lima Fernando, Passemard Sandrine, Sabéran-Djoneidi Délara, Nguyen Laurent, Lancaster Madeline, Sistonen Lea, Mezger Valérie
(A1 Refereed original research article in a scientific journal)
HSFs drive transcription of distinct genes and enhancers during oxidative stress and heat shock (2022)
- Nucleic Acids Research
Himanen Samu V, Puustinen Mikael C, Da Silva Alejandro J, Vihervaara Anniina, Sistonen Lea
(A1 Refereed original research article in a scientific journal)
Interplay between mammalian heat shock factors 1 and 2 in physiology and pathology (2022)
- FEBS Journal
Roos-Mattjus Pia, Sistonen Lea
(A2 Refereed review article in a scientific journal )
Quantifying RNA synthesis at rate-limiting steps of transcription using nascent RNA-sequencing data (2022)
- STAR protocols
Rabenius Adelina, Chandrakumaran Sajitha, Sistonen Lea, Vihervaara Anniina
(A1 Refereed original research article in a scientific journal)
Stress-induced transcriptional memory accelerates promoter-proximal pause release and decelerates termination over mitotic divisions (2021)
- Molecular Cell
Vihervaara Anniina, Mahat Dig Bijay, Himanen Samu V, Blom Malin AH, Lis John T, Sistonen Lea
(A1 Refereed original research article in a scientific journal)
The 2021 FASEB Virtual Catalyst Conference on Extracellular and Organismal Proteostasis in Health and Disease, February 3-4, 2021 (2021)
- FASEB Journal
Lior Chen, Hodge Francesca, De-Souza Evandro A, Bourboulia Dimitra, Calderwood Stuart K, David Della, Drummond D. Allan, Edkins Adrienne, Morimoto Richard I, Prahlad Veena, Rechavi Oded, Sistonen Lea, Wilson Mark, Wiseman R. Luke, Zanetti Maurizio, Taylor Rebecca, Scherz-Shouval Ruth, van Oosten-Hawle Patricija
(B1 Non-refereed article in a scientific journal)
Therapeutic Potential of Targeting the SUMO Pathway in Cancer (2021)
- Cancers
Kukkula Antti, Ojala Veera K., Mendez Lourdes M, Sistonen Lea, Elenius Klaus, Sundvall Maria
(A2 Refereed review article in a scientific journal )
Heat Shock Factor 2 Protects against Proteotoxicity by Maintaining Cell-Cell Adhesion (2020)
- Cell Reports
Jenny Joutsen, Alejandro Jose Da Silva, Jens Christian Luoto, Marek Andrzej Budzynski, Anna Serafia Nylund, Aurelie de Thonel, Jean-Paul Concordet, Valérie Mezger, Délara Saberan-Djoneidi, Eva Henriksson, Lea Sistonen
(A1 Refereed original research article in a scientific journal)
Molecular Mechanisms of Heat Shock Factors in Cancer (2020)
- Cells
Mikael Christer Puustinen, Lea Sistonen
(A2 Refereed review article in a scientific journal )
Co-chaperones TIMP2 and AHA1 Competitively Regulate Extracellular HSP90:Client MMP2 Activity and Matrix Proteolysis (2019)
- Cell Reports
Baker-Williams AJ, Hashmi F, Nski MAB, Woodford MR, Gleicher S, Himanen SV, Makedon AM, Friedman D, Cortes S, Namek S, Stetler-Stevenson WG, Bratslavsky G, Bah A, Mollapour M, Sistonen L, Bourboulia D
(A1 Refereed original research article in a scientific journal)
New insights into transcriptional reprogramming during cellular stress (2019)
- Journal of Cell Science
Samu V. Himanen, Lea Sistonen
(A2 Refereed review article in a scientific journal )