Iida Martiskainen
PhD
iimama@utu.fi +358 29 450 4584 +358 50 527 4151 Kiinamyllynkatu 10 Turku |
In vitro diagnostics, immunoassays, point-of-care diagnostics, rapid testing devices
My field of research is in vitro diagnostics, particularly technologies and applications suitable for point-of-care diagnostics. I have expertise especially in immunoassay methods and various sensitive and quantitative labeling technologies applicable to them. I have worked extensively with different biomarkers, including those for viral infections, cancer, and cardiovascular diseases.
I have studied interfering factors present in clinical samples, their impact on the performance of immunoassays, and various technical applications to eliminate them in assays, particularly in rapid tests. My doctoral dissertation focused on sensitive and quantitative lateral flow assays. In my current research, I combine this expertise with microfluidics and 3D-printed materials to develop automated test devices for point-of-care testing of complex diagnostic assays typically requiring central laboratory analysis.
Research interests:
- High-sensitivity point-of-care applications
- Immunoassay-based technologies
- Rapid diagnostics for resource-constrained settings
- Sustainability of diagnostic devices
- Lab-on-a-chip
- Microfluidics
- 3D-printing
Projects:
- 1/2025 - 12/2025, The Research Fund of the Finnish Red Cross Blood Service, Research project grant “Point-of-care test for the multiplexed and ratiometric detection of iron deficiency associated biomarkers in blood donors”
- 5/2022 - 6/2023, Business Finland Co-Innovation, Future of Diagnostics – FUDIS (40932/31/2020)
- Clinical Chemistry
- Molecular Biotechnology
- Laboratory courses
- Improved sensitivity and automation of a multi-step upconversion lateral flow immunoassay using a 3D-printed actuation mechanism (2024)
- Analytical and Bioanalytical Chemistry
- Spectrally separated dual-label upconversion luminescence lateral flow assay for cancer-specific STn-glycosylation in CA125 and CA15-3 (2024)
- Analytical and Bioanalytical Chemistry
- Double-Antigen Lateral Flow Immunoassay for the Detection of Anti-HIV-1 and -2 Antibodies Using Upconverting Nanoparticle Reporters (2021)
- Sensors
- Sensitive and quantitative detection of Cardiac Troponin I with upconverting nanoparticle lateral flow test with minimized interference (2021)
- Scientific Reports
- Sensitive and quantitative lateral flow tests – with upconverting nanoparticle reporter technology (2021) Martiskainen Iida
- Upconverting nanoparticle reporter–based highly sensitive rapid lateral flow immunoassay for hepatitis B virus surface antigen (2021)
- Analytical and Bioanalytical Chemistry
- Microparticle - based platform for point-of-care immunoassays (2018)
- Analytical Biochemistry
- A lateral flow immunoassay with upconverting nanoparticle-based detection for indirect measurement of interferon response by the level of MxA (2017)
- Journal of Medical Virology