Tapio Lönnberg
PhD
Turku Bioscience Centre taplon@utu.fi Tykistökatu 6 Turku ORCID-tunniste: https://orcid.org/orcid.org/0000-0003-4484-5657 |
Asiantuntijuusalueet
Single-cell genomics, immunology
Single-cell genomics, immunology
Tutkimusyhteisö tai tutkimusaihe
Single-cell immunogenomics research group at Turku Bioscience Centre; InFLAMES Flagship
Single-cell immunogenomics research group at Turku Bioscience Centre; InFLAMES Flagship
Biografia
- Phd 2012, University of Turku, supervised by Prof. Riitta Lahesmaa and Prof. Matej Orešič
- Postdoc 2023-2016, Teichmann lab, EMBL-EBI and Wellcome Trust Sanger Institute, UK
- Academy of Finland postdoc 2017-2020, Turku Bioscience Centre, University of Turku
- 2021- Group Leader at InFLAMES Flagship
- Secretary of the Finnish Society for Immunology
Tutkimus
Our research aims at gaining deeper understanding of cell fate decisions in the immune system. We leverage single-cell and spatial omics to explore phenotypic heterogeneity beyond the immune cell subsets defined by the expression of cell surface markers. Our current research encompasses arthritic, autoimmune and cardiovascular diseases, aiming to identify core gene modules that are associated with disease state and can be exploited for more efficient diagnosis, patient stratification, and therapies.
Opetus
- Modern biotechnologies and bioinformatics
- Medical biotechnology
- Advanced Immunology
Julkaisut 
3/3
- Holistic Systems Biology Approaches to Molecular Mechanisms of Human Helper T Cell Differentiation to Functionally Distinct Subsets (2013)
- Scandinavian Journal of Immunology
(A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä ) - An integrative computational systems biology approach identifies differentially regulated dynamic transcriptome signatures which drive the initiation of human T helper cell differentiation (2012)
- BMC Genomics
(A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä ) - Quantitative proteomics analysis of the nuclear fraction of human CD4+ cells in the early phases of IL-4-induced Th2 differentiation (2010)
- Molecular and Cellular Proteomics
(A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä ) - A human ImmunoChip cDNA microarray provides a comprehensive tool to study immune responses (2005) Nikula T, West A, Katajamaa M, Lonnberg T, Sara R, Aittokallio T, Nevalainen OS, Lahesmaa R
(A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä )
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