Tapio Lönnberg
PhD
Turku Bioscience Centre taplon@utu.fi Tykistökatu 6 Turku ORCID-tunniste: https://orcid.org/orcid.org/0000-0003-4484-5657 |
Asiantuntijuusalueet
Single-cell genomics, immunology
Single-cell genomics, immunology
Tutkimusyhteisö tai tutkimusaihe
Single-cell immunogenomics research group at Turku Bioscience Centre; InFLAMES Flagship
Single-cell immunogenomics research group at Turku Bioscience Centre; InFLAMES Flagship
Biografia
- Phd 2012, University of Turku, supervised by Prof. Riitta Lahesmaa and Prof. Matej Orešič
- Postdoc 2023-2016, Teichmann lab, EMBL-EBI and Wellcome Trust Sanger Institute, UK
- Academy of Finland postdoc 2017-2020, Turku Bioscience Centre, University of Turku
- 2021- Group Leader at InFLAMES Flagship
- Secretary of the Finnish Society for Immunology
Tutkimus
Our research aims at gaining deeper understanding of cell fate decisions in the immune system. We leverage single-cell and spatial omics to explore phenotypic heterogeneity beyond the immune cell subsets defined by the expression of cell surface markers. Our current research encompasses arthritic, autoimmune and cardiovascular diseases, aiming to identify core gene modules that are associated with disease state and can be exploited for more efficient diagnosis, patient stratification, and therapies.
Opetus
- Modern biotechnologies and bioinformatics
- Medical biotechnology
- Advanced Immunology
Julkaisut 
1/6
- Comparing spatial transcriptomics technologies for resolving immune infiltration in arthritic human hip joint tissue (2026) Rydgren, Emilie; Kotilainen, Sanna; Piipponen, Minna; Lönnberg, Tapio; Mikkola, Lea
(Konferenssiposteri) - Identifying immune mediators of osteoarthritis pain (2026) Metso, Sara; Lönnberg, Tapio; Mikkola, Lea
(Konferenssiposteri) - Unraveling the mechanisms of autoimmunity in Systemic Lupus Erythematosus with single-cell immunoprofiling (2026) Joshi, Shreya; Mikkola, Lea; Hänninen, Arno; Lönnberg, Tapio
(Konferenssiposteri) - Breast cancer remodels lymphatics in sentinel lymph nodes (2025)
- Nature Communications
(A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä ) - COMPARISON OF TWO HIGH-RESOLUTION SPATIAL TRANSCRIPTOMICS TECHNOLOGIES TO STUDY SYNOVIAL IMMUNE INFILTRATION IN OSTEOARTHRITIS AND RHEUMATOID ARTHRITIS (2025)
- Osteoarthritis and Cartilage
(Abstrakti) - Identifying immune mediators of osteoarthritis pain (2025) Metso, Sara; Lönnberg, Tapio; Mikkola, Lea
(Konferenssiposteri) - Integrin β1 activity controls colony morphology during human pluripotent stem cell state transitions (2025)
- Stem Cell Reports
(A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä ) - MicroRNA gene dynamics in immune cell subpopulations during aging and atherosclerosis disease development at single-cell resolution (2025)
- Genome Medicine
(A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä ) - Nextpie: a web-based reporting tool and database for reproducible nextflow pipelines (2025)
- Bioinformatics Advances
(A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä ) - Single-cell RNA-seq analysis of longitudinal CD4+ T cell samples reveals cell-type-specific changes during early stages of type 1 diabetes (2025)
- Genome Medicine
(A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä )
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