Johanna Schleutker
PhD, Professor of Medical Genetics
Cancer genetics; hereditary cancer; genomics; human genetics
Johanna Schleutker got her PhD in 1995 in University of Turku, Faculty of Medicine.The topic of her doctoral thesis was "Linkage disequilibrium is Salla disease; positioning of the sialic acid transport defect". She then moved to University of Tampere, and did her post doc in 1996-1998 in the Cancer Genetics research group of Professor Olli Kallioniemi. Her career continued in the US where she spent the years of 1999-2000 working as a research associate at the National Human Genome Research Institute, National Institutes of Health, Bethesda, MD. During the NIH years, she studied genetics of familial prostate cancer in the group of Dr. Jeffrey M.Trent. After her return to Finland, Schleutker started her own research group in 2001 at the Insitute of Medical Technology, University of Tampere, and has ever since focused her studies on genetics and genetic susceptibility of prostate and breast cancer. Schleutker got a professorship in University of Tampere in 2008. In 2011 she started as a professor of medical genetics in University of Turku.
The Schleutker group "Genetic Predisposition to Cancer" is studying both breast and prostate cancer genetics, the main emphasis being on prostate cancer. Of all cancers, prostate cancer (PrCa) has been reported as one of the most heritable diseases: genetic factors have been estimated to account for 57% of the risk. The goal is to identify and characterize predisposing genes and variants, especially those affecting aggressive outcome, including treatment responses to therapies. Further, the aim is to develop tools for prognostic purposes, i.e. prognostic biomarkers. The group has identified many significant genomic risk regions, candidate genes and variants, which have been then further profiled and characterized by functional studies. The group has produced (by 2021) 12 PhD degrees and published over 190 original, peer-reviewed articles in international journals.
Genetics, cancer genetics, hereditary cancer, genomics, molecular biology.
- ANO7 expression in the prostate modulates mitochondrial function and lipid metabolism (2025)
- Cell Communication and Signaling
Löf, Christoffer; Sultana, Nasrin; Goel, Neha; Heron, Samuel; Wahlström, Gudrun; House, Andrew; Holopainen, Minna; Käkelä, Reijo; Schleutker, Johanna
- Spatial profiling of ANO7 in prostate tissue: links to AR-signalling-associated lipid metabolism and inflammation (2025) Metsälä, Olli; Wahlström, Gudrun; Goel, Neha; Miihkinen, Mitro; Taimen, Pekka; Schleutker, Johanna
- A PSA SNP associates with cellular function and clinical outcome in men with prostate cancer (2024) Srinivasan, Srilakshmi; Kryza, Thomas; Bock, Nathalie; Tse, Brian W. C.; Sokolowski, Kamil A.; Janaththani, Panchadsaram; Fernando, Achala; Moya, Leire; Stephens, Carson; Dong, Ying; Röhl, Joan; Alinezhad, Saeid; Vela, Ian; Perry-Keene, Joanna L.; Buzacott, Katie; Nica, Robert; Gago-Dominguez, Manuela; Schleutker, Johanna; Maier, Christiane; Muir, Kenneth; Tangen, Catherine M.; Gronberg, Henrik; Pashayan, Nora; Albanes, Demetrius; Wolk, Alicja; Stanford, Janet L.; Berndt, Sonja I.; Mucci, Lorelei A.; Koutros, Stella; Cussenot, Olivier; Sorensen, Karina Dalsgaard; Grindedal, Eli Marie; Travis, Ruth C.; Haiman, Christopher A.; MacInnis, Robert J.; Vega, Ana; Wiklund, Fredrik; Neal, David E.; Kogevinas, Manolis; Penney, Kathryn L.; Nordestgaard, Børge G.; Brenner, Hermann; John, Esther M.; Gamulin, Marija; Claessens, Frank; Melander, Olle; Dahlin, Anders; Stattin, Pär; Hallmans, Göran; Häggström, Christel; Johansson, Robert; Thysell, Elin; Rönn, Ann-Charlotte; Li, Weiqiang; Brown, Nigel; Dimeski, Goce; Shepherd, Benjamin; Dadaev, Tokhir; Brook, Mark N.; Spurdle, Amanda B.; Stenman, Ulf-Håkan; Koistinen, Hannu; Kote-Jarai, Zsofia; Klein, Robert J.; Lilja, Hans; Ecker, Rupert C.; Eeles, Rosalind; Clements, Judith; Batra, Jyotsna; The IMPACT Study; The PROFILE Study Steering Committee; The Practical Consortium; The Australian Prostate Cancer BioResource
- Cluster effect for SNP-SNP interaction pairs for predicting complex traits (2024) Li,n Hui-Yi; Mazumder, Harun; Sarkar, Indrani; Huang, Po-Yu; Eeles, Rosalind A.; Kote-Jarai, Zsofia; Muir, Kenneth R.; Schleutker, Johanna; Pashayan, Nora; Batra, Joytsna; Neal, David E.; Nielsen, Sune F.; Nordestgaard, Börge G.; Grönberg, Henrik; Wiklund, Fredrik; MacInnis, Robert J.; Haiman, Christopher A.; Travis, Ruth C.; Stanford, Janet L.; Kibel, Adam S.; Cybulski, Cezary; Khaw, Kay-Tee; Maier, Christiane; Thibodeau, Stephen N.; Teixeira, Manuel R.; Cannon-Albright, Lisa; Brenner, Hermann; Kaneva, Radka; Pandha, Hardev; The PRACTICAL consortium; Park, Jong Y.
- Kuura—An automated workflow for analyzing WES and WGS data (2024) Jambulingam Dhanaprakash, Rathinakannan Venkat Subramaniam, Heron Samuel, Schleutker Johanna, Fey Vidal
- Rare Germline Variants in DNA Repair Genes Detected in BRCA-Negative Finnish Patients with Early-Onset Breast Cancer (2024) Kurkilahti, Viivi; Rathinakannan, Venkat Subramaniam; Nynäs, Erja; Goel, Neha; Aittomäki, Kristiina; Nevanlinna, Heli; Fey, Vidal; Kankuri-Tammilehto, Minna; Schleutker, Johanna
- Characterizing prostate cancer risk through multi-ancestry genome-wide discovery of 187 novel risk variants (2023) Wang A., Shen J., Rodriguez A.A., Saunders E.J., Chen F., Janivara R., Darst B.F., Sheng X., Xu Y., Chou A.J., Benlloch S., Dadaev T., Brook M.N., Plym A., Sahimi A., Hoffman T.J., Takahashi A., Matsuda K., Momozawa Y., Fujita M., Laisk T., Figuerêdo J., Muir K., Ito S., Liu X., Yamanashi Y., Furukawa Y., Morisaki T., Murakami Y., Muto K., Nagai A., Obara W., Yamaji K., Takahashi K., Asai S., Takahashi Y., Suzuki T., Sinozaki N., Yamaguchi H., Minami S., Murayama S., Yoshimori K., Nagayama S., Obata D., Higashiyama M., Masumoto A., Koretsune Y., Uchio Y., Kubo M., Kamatani Y., Lophatananon A., Wan P., Andrews C., Lori A., Choudhury P.P., Schleutker J., Tammela T.L.J., Sipeky C., Auvinen A., Giles G.G., Southey M.C., MacInnis R.J., Cybulski C., Wokolorczyk D., Lubinski J., Rentsch C.T., Cho K., Mcmahon B.H., Neal D.E., Donovan J.L., Hamdy F.C., Martin R.M., Nordestgaard B.G., Nielsen S.F., Weischer M., Bojesen S.E., Røder A., Stroomberg H.V., Batra J., Chambers S., Horvath L., Clements J.A., Tilly W., Risbridger G.P., Gronberg H., Aly M., Szulkin R., Eklund M., Nordstrom T., Pashayan N., Dunning A.M., Ghoussaini M., Travis R.C., Key T.J., Riboli E., Park J.Y., Sellers T.A., Lin H.Y., Albanes D., Weinstein S., Cook M.B., Mucci L.A., Giovannucci E., Lindstrom S., Kraft P., Hunter D.J., Penney K.L., Turman C., Tangen C.M., Goodman P.J., Thompson I.M., Hamilton R.J., Fleshner N.E., Finelli A., Parent M.É., Stanford J.L., Ostrander E.A., Koutros S., Beane Freeman L.E., Stampfer M., Wolk A., Håkansson N., Andriole G.L., Hoover R.N., Machiela M.J., Sørensen K.D., Borre M., Blot W.J., Zheng W., Yeboah E.D., Mensah J.E., Lu Y.J., Zhang H.W., Feng N., Mao X., Wu Y., Zhao S.C., Sun Z., Thibodeau S.N., McDonnell S.K., Schaid D.J., West C.M.L., Barnett G., Maier C., Schnoeller T., Luedeke M., Kibel A.S., Drake B.F., Cussenot O., Cancel-Tassin G., Menegaux F., Truong T., Koudou Y.A., John E.M., Grindedal E.M., Maehle L., Khaw K.T., Ingles S.A., Stern M.C., Vega A., Gómez-Caamaño A., Fachal L., Rosenstein B.S., Kerns S.L., Ostrer H., Teixeira M.R., Paulo P., Brandão A., Watya S., Lubwama A., Bensen J.T., Butler E.N., Mohler J.L., Taylor J.A., Kogevinas M., Dierssen-Sotos T., Castaño-Vinyals G., Cannon-Albright L., Teerlink C.C., Huff C.D., Pilie P., Yu Y., Bohlender R.J., Gu J., Strom S.S., Multigner L., Blanchet P., Brureau L., Kaneva R., Slavov C., Mitev V., Leach R.J., Brenner H., Chen X., Holleczek B., Schöttker B., Klein E.A., Hsing A.W., Kittles R.A., Murphy A.B., Logothetis C.J., Kim J., Neuhausen S.L., Steele L., Ding Y.C., Isaacs W.B., Nemesure B., Hennis A.J.M., Carpten J., Pandha H., Michael A., De Ruyck K., De Meerleer G., Ost P., Xu J., Razack A., Lim J., Teo S.H., Newcomb L.F., Lin D.W., Fowke J.H., Neslund-Dudas C.M., Rybicki B.A., Gamulin M., Lessel D., Kulis T., Usmani N., Abraham A., Singhal S., Parliament M., Claessens F., Joniau S., Van den Broeck T., Gago-Dominguez M., Castelao J.E., Martinez M.E., Larkin S., Townsend P.A., Aukim-Hastie C., Bush W.S., Aldrich M.C., Crawford D.C., Srivastava S., Cullen J., Petrovics G., Casey G., Wang Y., Tettey Y., Lachance J., Tang W., Biritwum R.B., Adjei A.A., Tay E., Truelove A., Niwa S., Yamoah K., Govindasami K., Chokkalingam A.P., Keaton J.M., Hellwege J.N., Clark P.E., Jalloh M., Gueye S.M., Niang L., Ogunbiyi O., Shittu O., Amodu O., Adebiyi A.O., Aisuodionoe-Shadrach O.I., Ajibola H.O., Jamda M.A., Oluwole O.P., Nwegbu M., Adusei B., Mante S., Darkwa-Abrahams A., Diop H., Gundell S.M., Roobol M.J., Jenster G., van Schaik R.H.N., Hu J.J., Sanderson M., Kachuri L., Varma R., McKean-Cowdin R., Torres M., Preuss M.H., Loos R.J.F., Zawistowski M., Zöllner S., Lu Z., Van Den Eeden S.K., Easton D.F., Ambs S., Edwards T.L., Mägi R., Rebbeck T.R., Fritsche L., Chanock S.J., Berndt S.I., Wiklund F., Nakagawa H., Witte J.S., Gaziano J.M., Justice A.C., Mancuso N., Terao C., Eeles R.A., Kote-Jarai Z., Madduri R.K., Conti D.V., Haiman C.A.
- Evaluating approaches for constructing polygenic risk scores for prostate cancer in men of African and European ancestry (2023)
- American Journal of Human Genetics
Burcu F. Darst, Jiayi Shen, Ravi K. Madduri, Alexis A. Rodriguez, Yukai Xiao, Xin Sheng, Edward J. Saunders, Tokhir Dadaev, Mark N. Brook, Thomas J. Hoffmann, Kenneth Muir, Peggy Wan, Le Marchand Loic, Lynne Wilkens, Ying Wang, Johanna Schleutker, Robert J. MacInnis, Cezary Cybulski, David E. Neal, Børge G. Nordestgaard, Sune F. Nielsen, Jyotsna Batra, Judith A. Clements, Henrik Grönberg, Nora Pashayan, Ruth C. Travis, Jong Y. Park, Demetrius Albanes, Stephanie Weinstein, Lorelei A. Mucci, David J. Hunter, Kathryn L. Penney, Catherine M. Tangen, Robert J. Hamilton, Marie-Élise Parent, Janet L. Stanford, Stella Koutros, Alicja Wolk, Karina D. Sørensen, William J. Blot, Edward D. Yeboah, James E. Mensah, Yong-Jie Lu, Daniel J. Schaid, Stephen N. Thibodeau, Catharine M. West, Christiane Maier, Adam S. Kibel, Géraldine Cancel-Tassin, Florence Menegaux, Esther M. John, Grindedal Eli Marie, Kay-Tee Khaw, Sue A. Ingles, Ana Vega, Barry S. Rosenstein, Manuel R. Teixeira, Manolis Kogevinas, Lisa Cannon-Albright, Chad Huff, Luc Multigner, Radka Kaneva, Robin J. Leach, Hermann Brenner, Ann W. Hsing, Rick A. Kittles, Adam B. Murphy, Christopher J. Logothetis, Susan L. Neuhausen, William B. Isaacs, Barbara Nemesure, Anselm J. Hennis, John Carpten, Hardev Pandha, De Ruyck Kim, Jianfeng Xu, Azad Razack, Soo-Hwang Teo, Lisa F. Newcomb, Jay H. Fowke, Christine Neslund-Dudas, Benjamin A. Rybicki, Marija Gamulin, Nawaid Usmani, Frank Claessens, Manuela Gago-Dominguez, Castelao Jose Esteban, Paul A. Townsend, Dana C. Crawford, Gyorgy Petrovics, Graham Casey, Monique J. Roobol, Jennifer F. Hu, Sonja I. Berndt, Van Den Eeden Stephen K., Easton Douglas F., Chanock Stephen J., Cook Michael B., Wiklund Fredrik, Witte John S., Eeles Rosalind A., Kote-Jarai Zsofia, Watya Stephen, Gaziano John M., Justice Amy C., Conti David V., Haiman Christopher A.; Australian Prostate Cancer BioResource; NC-LA PCaP Investigators; Canary PASS Investigators
- FinnGen provides genetic insights from a well-phenotyped isolated population (2023) Kurki Mitja I., Karjalainen Juha, Palta Priit, Sipilä Timo P., Kristiansson Kati, Donner Kati M., Reeve Mary P., Laivuori Hannele, Aavikko Mervi, Kaunisto Mari A., Loukola Anu, Lahtela Elisa, Mattsson Hannele, Laiho Päivi, Parolo Pietro Della Briotta, Lehisto Arto A., Kanai Masahiro, Mars Nina, Rämö Joel, Kiiskinen Tuomo, Heyne Henrike O., Veerapen Kumar, Rüeger Sina, Lemmelä Susanna, Zhou Wei, Ruotsalainen Sanni, Pärn Kalle, Hiekkalinna Tero, Koskelainen Sami, Paajanen Teemu, Llorens Vincent, Gracia-Tabuenca Javier, Siirtola Harri, Reis Kadri, Elnahas Abdelrahman G., Sun Benjamin, Foley Christopher N., Aalto-Setälä Katriina, Alasoo Kaur, Arvas Mikko, Auro Kirsi, Biswas Shameek, Bizaki-Vallaskangas Argyro, Carpen Olli, Chen Chia-Yen, Dada Oluwaseun A., Ding Zhihao, Ehm Margaret G., Eklund Kari, Färkkilä Martti, Finucane Hilary, Ganna Andrea, Ghazal Awaisa, Graham Robert R., Green Eric M., Hakanen Antti, Hautalahti Marco, Hedman Åsa K., Hiltunen Mikko, Hinttala Reetta, Hovatta Iiris, Hu Xinli, Huertas-Vazquez Adriana, Huilaja Laura, Hunkapiller Julie, Jacob Howard, Jensen Jan-Nygaard, Joensuu Heikki, John Sally, Julkunen Valtteri, Jung Marc, Junttila Juhani, Kaarniranta Kai, Kähönen Mika, Kajanne Risto, Kallio Lila, Kälviäinen Reetta, Kaprio Jaakko, FinnGen, Kerimov Nurlan, Kettunen Johannes, Kilpeläinen Elina, Kilpi Terhi, Klinger Katherine, Kosma Veli-Matti, Kuopio Teijo, Kurra Venla, Laisk Triin, Laukkanen Jari, Lawless Nathan, Liu Aoxing, Longerich Simonne, Mägi Reedik, Mäkelä Johanna, Mäkitie Antti, Malarstig Anders, Mannermaa Arto, Maranville Joseph, Matakidou Athena, Meretoja Tuomo, Mozaffari Sahar V., Niemi Mari E. K., Niemi Marianna, Niiranen Teemu, O´Donnell Christopher J., Obeidat Ma´en, Okafo George, Ollila Hanna M., Palomäki Antti, Palotie Tuula, Partanen Jukka, Paul Dirk S., Pelkonen Margit, Pendergrass Rion K., Petrovski Slavé, Pitkäranta Anne, Platt Adam, Pulford David, Punkka Eero, Pussinen Pirkko, Raghavan Neha, Rahimov Fedik, Rajpal Deepak, Renaud Nicole A., Riley-Gillis Bridget, Rodosthenous Rodosthenis, Saarentaus Elmo, Salminen Aino, Salminen Eveliina, Salomaa Veikko, Schleutker Johanna, Serpi Raisa, Shen Huei-yi, Siegel Richard, Silander Kaisa, Siltanen Sanna, Soini Sirpa, Soininen Hilkka, Sul Jae Hoon, Tachmazidou Ioanna, Tasanen Kaisa, Tienari Pentti, Toppila-Salmi Sanna, Tukiainen Taru, Tuomi Tiinamaija, Turunen Joni A., Ulirsch Jacob C., Vaura Felix, Virolainen Petri, Waring Jeffrey, Waterworth Dawn, Yang Robert, Nelis Mari, Reigo Anu, Metspalu Andres, Milani Lili, Esko Tõnu, Fox Caroline, Havulinna Aki S., Perola Markus, Ripatti Samuli, Jalanko Anu, Laitinen Tarja, Mäkelä Tomi P., Plenge Robert, McCarthy Mark, Runz Heiko, Daly Mark J., Palotie Aarno
- NTHL1 is a recessive cancer susceptibility gene (2023) Nurmi Anna K., Pelttari Liisa M., Kiiski Johanna I., Khan Sofia, Nurmikolu Mika, Suvanto Maija, Aho Niina, Tasmuth Tiina, Kalso Eija, Schleutker Johanna, Kallioniemi Anne, Heikkilä Päivi; FinnGen, Aittomäki Kristiina, Blomqvist Carl, Nevanlinna Heli
- Observational and genetic associations between cardiorespiratory fitness and cancer : a UK Biobank and international consortia study (2023)
- British Journal of Cancer
Watts Eleanor L., Gonzales Tomas I., Strain Tessa, Saint-Maurice Pedro F., Bishop D. Timothy, Chanock Stephen J., Johansson Mattias, Keku Temitope O., Le Marchand Loic, Moreno Victor, Newcomb Polly A., Newton Christina C., Pai Rish K., Purdue Mark P., Ulrich Cornelia M., Smith-Byrne Karl, Van Guelpen Bethany, Eeles Rosalind A., Haiman Christopher A., Kote-Jarai Zsofia, Schumacher Fredrick R., Benlloch Sara, Olama Ali Amin Al, Muir Kenneth R., Berndt Sonja I., Conti David V., Wiklund Fredrik, Chanock Stephen J., Wang Ying, Tangen Catherine M., Batra Jyotsna, Clements Judith A., Grönberg Henrik, Pashayan Nora, Schleutker Johanna, Albanes Demetrius, Weinstein Stephanie J., Wolk Alicja, West Catharine M. L., Mucci Lorelei A., Cancel-Tassin Géraldine, Koutros Stella, Sørensen Karina Dalsgaard, Grindedal Eli Marie, Neal David E., Hamdy Freddie C., Donovan Jenny L., Travis Ruth C., Hamilton Robert J., Ingles Sue Ann, Rosenstein Barry S., Lu Yong-Jie, Giles Graham G., MacInnis Robert J., Kibel Adam S., Vega Ana, Kogevinas Manolis, Penney Kathryn L., Park Jong Y., Stanford Janet L., Cybulski Cezary, Nordestgaard Børge G., Nielsen Sune F., Brenner Hermann, Maier Christiane, Kim Jeri, John Esther M., Teixeira Manuel R., Neuhausen Susan L., De Ruyck Kim, Razack Azad, Newcomb Lisa F., Lessel Davor, Kaneva Radka, Usmani Nawaid, Claessens Frank, Townsend Paul A., Castelao Jose Esteban, Roobol Monique J., Menegaux Florence, Khaw Kay-Tee, Cannon-Albright Lisa, Pandha Hardev, Thibodeau Stephen N., Hunter David J., Kraft Peter, Blot William J., Riboli Elio, Day Felix R., Wijndaele Katrien, Wareham Nicholas J., Matthews Charles E., Moore Steven C., Brage Soren; The PRACTICAL consortium CRUK BPC3 CAPS PEGASUS; APCB BioResource (Australian Prostate Cancer BioResource)
- Transcripts of the Prostate Cancer-Associated Gene ANO7 Are Retained in the Nuclei of Prostatic Epithelial Cells (2023)
- International Journal of Molecular Sciences
Metsälä Olli, Wahlström Gudrun, Taimen Pekka, Kellokumpu-Lehtinen Pirkko-Liisa, Schleutker Johanna
- TREX1 p.A129fs and p.Y305C variants in a large multi-ethnic cohort of CADASIL-like unrelated patients (2023) Foddis M, Blumenau S, Holtgrewe M, Paquette K, Westra K, Alonso I, Macario MD, Morgadinho AS, Velon AG, Santo G, Santana I, Mönkäre S, Kuuluvainen L, Schleutker J, Pöyhönen M, Myllykangas L, Pavlovic A, Kostic V, Dobricic V, Lohmann E, Hanagasi H, Santos M, Guven G, Bilgic B, Bras J, Beule D, Dirnagl U, Guerreiro R, Sassi C
- Assessing the causal role of epigenetic clocks in the development of multiple cancers: a Mendelian randomization study (2022) Morales Berstein Fernanda, McCartney Daniel L, Lu Ake T, Tsilidis Konstantintus K, Bouras Emmanouil, Haycock Philip, Burrows Kimberley, Phipps Amanda I, Buchanan Dnaiel D, Cheng Iona; PRACTICAL consortium, Martin Richardo M, Davey Smith George, Relton Caroline L, Horvath Steve, Marioni Riccardo E, Richardson Tom G, Richmond Rebecca C
- Clinical features and spectrum of NOTCH3 variants in Finnish patients with cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) (2022)
- Acta Neurologica Scandinavica
Mönkäre Saana, Kuuluvainen Liina, Schleutker Johanna, Myllykangas Liisa, Pöyhönen Minna
- Genetic analysis reveals novel variants for vascular cognitive impairment (2022)
- Acta Neurologica Scandinavica
Mönkäre Saana, Kuuluvainen Liina, Schleutker Johanna, Bras Jose, Roine Susanna, Pöyhönen Minna, Guerreiro Rita, Myllykangas Liisa
- New insights into the genetic etiology of Alzheimer’s disease and related dementias (2022) Bellenguez C, Küçükali F, Jansen IE, Kleineidam L, Moreno-Grau S, Amin N, Naj AC, Campos-Martin R, Grenier-Boley B, Andrade V, Holmans PA, Boland A, Damotte V, Lee SJ, Costa MR, Kuulasmaa T, Yang Q, Rojas I, Bis JC, Yaqub A, Prokic I, Chapuis J, Ahmad S, Giedraitis V, Aarsland D, Garcia-Gonzalez P, Abdelnour C, Alarcón-Martín E, Alcolea D, Alegret M, Alvarez I, Álvarez V, Armstrong NJ, Tsolaki A, Antúnez C, Appollonio I, Arcaro M, Archetti S, Pastor AA, Arosio B, Athanasiu L, Bailly H, Banaj N, Baquero M, Barral S, Beiser A, Pastor AB, Below JE, Benchek P, Benussi L, Berr C, Besse C, Bessi V, Binetti G, Bizarro A, Blesa R, Boada M, Boerwinkle E, Borroni B, Boschi S, Bossù P, Bråthen G, Bressler J, Bresner C, Brodaty H, Brookes KJ, Brusco LI, Buiza-Rueda D, Bûrger K, Burholt V, Bush WS, Calero M, Cantwell LB, Chene G, Chung J, Cuccaro ML, Carracedo Á, Cecchetti R, Cervera-Carles L, Charbonnier C, Chen H, Chillotti C, Ciccone S, Claassen JAHR, Clark C, Conti E, Corma-Gómez A, Costantini E, Custodero C, Daian D, Dalmasso MC, Daniele A, Dardiotis E, Dartigues J, Deyn PP, Paiva Lopes K, Witte LD, Debette S, Deckert J, Ser T, Denning N, DeStefano A, Dichgans M, Diehl-Schmid J, Diez-Fairen M, Rossi PD, Djurovic S, Duron E, Düzel E, Dufouil C, Eiriksdottir G, Engelborghs S, Escott-Price V, Espinosa A, Ewers M, Faber KM, Fabrizio T, Nielsen SF, Fardo DW, Farotti L, Fenoglio C, Fernández-Fuertes M, Ferrari R, Ferreira CB, Ferri E, Fin B, Fischer P, Fladby T, Fließbach K, Fongang B, Fornage M, Fortea J, Foroud TM, Fostinelli S, Fox NC, Franco-Macías E, Bullido MJ, Frank-García A, Froelich L, Fulton-Howard B, Galimberti D, García-Alberca JM, Garcia-Madrona S, Garcia-Ribas G, Ghidoni R, Giegling I, Giorgio G, Goate AM, Goldhardt O, Gomez-Fonseca D, González-Pérez A, Graff C, Grande G, Green E, Grimmer T, Grünblatt E, Grunin M, Gudnason V, Guetta-Baranes T, Haapasalo A, Hadjigeorgiou G, Haines JL, Hamilton-Nelson KL, Hampel H, Hanon O, Hardy J, Hartmann AM, Hausner L, Harwood J, Heilmann-Heimbach S, Helisalmi S, Heneka MT, Hernández I, Herrmann MJ, Hoffmann P, Holmes C, Holstege H, Vilas RH, Hulsman M, Humphrey J, Biessels GJ, Jian X, Johansson C, Jun GR, Kastumata Y, Kauwe J, Kehoe PG, Kilander L, Ståhlbom AK, Kivipelto M, Koivisto A, Kornhuber J, Kosmidis MH, Kukull WA, Kuksa PP, Kunkle BW, Kuzma AB, Lage C, Laukka EJ, Launer L, Lauria A, Lee C, Lehtisalo J, Lerch O, Lleó A, Longstreth W, Lopez O, Munain AL, Love S, Löwemark M, Luckcuck L, Lunetta KL, Ma Y, Macías J, MacLeod CA, Maier W, Mangialasche F, Spallazzi M, Marquié M, Marshall R, Martin ER, Montes AM, Rodríguez CM, Masullo C, Mayeux R, Mead S, Mecocci P, Medina M, Meggy A, Mehrabian S, Mendoza S, Menéndez-González M, Mir P, Moebus S, Mol M, Molina-Porcel L, Montrreal L, Morelli L, Moreno F, Morgan K, Mosley T, Nöthen MM, Muchnik C, Mukherjee S, Nacmias B, Ngandu T, Nicolas G, Nordestgaard BG, Olaso R, Orellana A, Orsini M, Ortega G, Padovani A, Paolo C, Papenberg G, Parnetti L, Pasquier F, Pastor P, Peloso G, Pérez-Cordón A, Pérez-Tur J, Pericard P, Peters O, Pijnenburg YAL, Pineda JA, Piñol-Ripoll G, Pisanu C, Polak T, Popp J, Posthuma D, Priller J, Puerta R, Quenez O, Quintela I, Thomassen JQ, Rábano A, Rainero I, Rajabli F, Ramakers I, Real LM, Reinders MJT, Reitz C, Reyes-Dumeyer D, Ridge P, Riedel-Heller S, Riederer P, Roberto N, Rodriguez-Rodriguez E, Rongve A, Allende IR, Rosende-Roca M, Royo JL, Rubino E, Rujescu D, Sáez ME, Sakka P, Saltvedt I, Sanabria Á, Sánchez-Arjona MB, Sanchez-Garcia F, Juan PS, Sánchez-Valle R, Sando SB, Sarnowski C, Satizabal CL, Scamosci M, Scarmeas N, Scarpini E, Scheltens P, Scherbaum N, Scherer M, Schmid M, Schneider A, Schott JM, Selbæk G, Seripa D, Serrano M, Sha J, Shadrin AA, Skrobot O, Slifer S, Snijders GJL, Soininen H, Solfrizzi V, Solomon A, Song Y, Sorbi S, Sotolongo-Grau O, Spalletta G, Spottke A, Squassina A, Stordal E, Tartan JP, 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- Prostate cancer risk stratification improvement across multiple ancestries with new polygenic hazard score (2022)
- Prostate Cancer and Prostatic Diseases
Huynh-Le Minh-Phuong, Karunamuni Roshan, Fan Chun Chieh, Asona Lui, Thompson Wesley K., Martinez Maria Elena, Eeles Rosalind A., Kote-Jarai Zsofia, Muir Kenneth R., Lophatananon Artitaya, Schleutker Johanna, Pashayan Nora, Batra Jyotsna, Grönberg Henrik, Neal David E., Nordestgaard Børge G., Tangen Catherine M., MacInnis Robert J., Wolk Alicja, Albanes Demetrius, Haiman Christopher A., Travis Ruth C., Blot William J., Stanford Janet L., Mucci Lorelei A., West Catharine M. L., Nielsen Sune F., Kibel Adam S., Cussenot Olivier, Berndt Sonja I., Koutros Stella, Sørensen Karina Dalsgaard, Cybulski Cezary, Grindedal Eli Marie, Menegaux Florence, Park Jong Y., Ingles Sue A., Maier Christiane, Hamilton Robert J., Rosenstein Barry S., Lu Yong-Jie, Watya Stephen, Vega Ana, Kogevinas Manolis, Wiklund Fredrik, Penney Kathryn L., Huff Chad D., Teixeira Manuel R., Multigner Luc, Leach Robin J., Brenner Hermann, John Esther M., Kaneva Radka, Logothetis Christopher J., Neuhausen Susan L., De Ruyck Kim, Ost Piet, Razack Azad, Newcomb Lisa F., Fowke Jay H., Gamulin Marija, Abraham Aswin, Claessens Frank, Castelao Jose Esteban, Townsend Paul A., Crawford Dana C., Petrovics Gyorgy, van Schaik Ron H. N., Parent Marie-Élise, Hu Jennifer J., Zheng Wei, collaborators UKGPCS, APCB (Australian Prostate Cancer BioResource), NC-LA PCaP Investigators, The IMPACT Study Steering Committee and Collaborators, Canary PASS Investigators, The Profile Study Steering Committee, The PRACTICAL Consortium, Mills Ian G., Andreassen Ole A., Dale Anders M., Seibert Tyler M.
- The variant rs77559646 associated with aggressive prostate cancer disrupts ANO7 mRNA splicing and protein expression (2022) Wahlström Gudrun, Heron Samuel, Knuuttila Matias, Kaikkonen Elina, Tulonen Nea, Metsälä Olli, Lof Christoffer, Ettala Otto, Boström Peter J., Taimen Pekka, Poutanen Matti, Schleutker Johanna
- Additional SNPs improve risk stratification of a polygenic hazard score for prostate cancer (2021)
- Prostate Cancer and Prostatic Diseases
Karunamuni Roshan A., Huynh-Le Minh-Phuong, Fan Chun C., Thompson Wesley, Eeles Rosalind A., Kote-Jarai Zsofia, Muir Kenneth, Lophatananon Artitaya, Schleutker Johanna, Pashayan Nora, Batra Jyotsna, Grönberg Henrik, Walsh Eleanor I., Turner Emma L., Lane Athene, Martin Richard M., Neal David E., Donovan Jenny L., Hamdy Freddie C., Nordestgaard Børge G., Tangen Catherine M., MacInnis Robert J., Wolk Alicja, Albanes Demetrius, Haiman Christopher A., Travis Ruth C., Stanford Janet L., Mucci Lorelei A., West Catharine M. L., Nielsen Sune F., Kibel Adam S., Wiklund Fredrik, Cussenot Olivier, Berndt Sonja I., Koutros Stella, Sørensen Karina Dalsgaard, Cybulski Cezary, Grindedal Eli Marie, Park Jong Y., Ingles Sue A., Maier Christiane, Hamilton Robert J., Rosenstein Barry S., Vega Ana, Kogevinas Manolis, Penney Kathryn L., Teixeira Manuel R., Brenner Hermann, John Esther M., Kaneva Radka, Logothetis Christopher J., Neuhausen Susan L., Razack Azad, Newcomb Lisa F., Gamulin Marija, Usmani Nawaid, Claessens Frank, Gago-Dominguez Manuela, Townsend Paul A., Roobol Monique J., Zheng Wei, Mills Ian G., Andreassen Ole A., Dale Anders M., Seibert Tyler M.; collaborators UKGPCS; APCB BioResource (Australian Prostate Cancer BioResource); The IMPACT Study Steering Committee and Collaborators; Canary PASS Investigators; The Profile Study Steering Committee; The PRACTICAL Consortium
