Tuomas Huovinen
tuohuo@utu.fi +358 29 450 4588 +358 50 476 5558 Kiinamyllynkatu 10 Turku |
Mutagenesis, recombinant antibodies, phage display, directed evolution
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- Improving genotyped functional screening: A versatile closed-tube PCR for Illumina library generation reduces background sequences in multiplexed sequencing (2026)
- SLAS Technology
- Advancing recombinant antibody production in E. coli: Optimization of expression and purification via dual GFP promoter and imaging technology (2025)
- Protein Expression and Purification
- Controlled labelling of tracer antibodies for time-resolved fluorescence-based immunoassays (2024)
- Scientific Reports
- Epitope-specific antibody fragments block aggregation of AGelD187N, an aberrant peptide in gelsolin amyloidosis (2024)
- Journal of Biological Chemistry
- Genotyped functional screening of soluble Fab clones enables in-depth analysis of mutation effects (2023)
- Scientific Reports
- Synonymous Codons and Hydrophobicity Optimization of Post-translational Signal Peptide PelB Increase Phage Display Efficiency of DARPins (2022)
- ACS Synthetic Biology
- Combinatorial mutagenesis with alternative CDR-L1 and-H2 loop lengths contributes to affinity maturation of antibodies (2021)
- New Biotechnology
- Multiplexed Affinity Characterization of Protein Binders Directly from a Crude Cell Lysate by Covalent Capture on Suspension Bead Arrays (2021)
- Analytical Chemistry
- Site-Specific Linking of an Oligonucleotide to Mono- and Bivalent Recombinant Antibodies with SpyCatcher-SpyTag System for Immuno-PCR (2020)
- ACS Omega
- Split & mix assembly of DNA libraries for ultrahigh throughput on-bead screening of functional proteins (2020)
- Nucleic Acids Research
UTU Research Portal