Xiang-Guo Li
Associate Professor
Turku PET Centre, University of Turku xiali@utu.fi Kiinamyllynkatu 10 Turku ORCID identifier: https://orcid.org/0000-0002-9118-7223 |
Radiochemistry, Radiopharmaceuticals, PET imaging, New drug development
Radiochemistry, Radiopharmaceuticals, InFLAMES Flagship
I am a radiochemist and medicinal chemist working at Turku PET Centre, University of Turku, Finland. I received my PhD degree from the Institute of Biomedicine, Faculty of Medicine, University of Turku, in 2008. Then I was at a Post-doctoral position funded by the Academy of Finland during 2010-2012. I received my Docentship in 2012 from University of Turku. Since 2013, I have been working at Turku PET Centre. At present, I work as an Assistant Professor in Radiochemistry, and Principal Investigator in the InFLAMES Research Flagship.
Basic research in radiochemistry including methodological development for radiosynthesis and radiolabeling techniques. We have been able to radiolabel many types of molecules including small organic compounds, peptides, antibody and antibody fragments, oligonucleotides, oligosaccharides etc.
Development of new radiopharmaceuticals for PET imaging of inflammatory diseases and immunological diseases.
The radiolabeled molecules are for imaging diseases or for studying disease machanisms with PET.
I teach in the courses of Radiopharmaceutical Chemistry, Radiolabeling techniques, Measuring techniques in radiochemistry, PET Basics, and supervise BSc, MSc and PhD students.
- Folate receptor-targeted positron emission tomography of experimental autoimmune encephalomyelitis in rats (2019)
- Journal of Neuroinflammation
(A1 Refereed original research article in a scientific journal) - Safety Study of Single-Dose Intravenously Administered DOTA-Siglec-9 Peptide in Sprague Dawley Rats (2019)
- International Journal of Toxicology
(A1 Refereed original research article in a scientific journal) - Adventures in radiosynthesis of clinical grade [68Ga]Ga-DOTA-Siglec-9 (2018)
- RSC Advances
(A1 Refereed original research article in a scientific journal) - Aluminum fluoride-18 labeled folate enables in vivo detection of atherosclerotic plaque inflammation by positron emission tomography (2018)
- Scientific Reports
(A1 Refereed original research article in a scientific journal) - Evaluation of 68Ga-labeled peptide tracer for detection of gelatinase expression after myocardial infarction in rat (2018)
- Journal of Nuclear Cardiology
(A1 Refereed original research article in a scientific journal) - Exploring Alternative Radiolabeling Strategies for Sialic Acid-Binding Immunoglobulin-Like Lectin 9 Peptide: [68Ga]Ga- and [18F]AlF-NOTA-Siglec-9 (2018)
- Molecules
(A1 Refereed original research article in a scientific journal) - In Vivo Imaging of Inflammation and Infection (2018)
- Contrast Media and Molecular Imaging
(B1 Non-refereed article in a scientific journal) - 18-kDa translocator protein ligand 18F-FEMPA: Biodistribution and uptake into atherosclerotic plaques in mice (2017)
- Journal of Nuclear Cardiology
(A1 Refereed original research article in a scientific journal) - Comparison of Ga-68-DOTA-Siglec-9 and F-18-Fluorodeoxyribose-Siglec-9: Inflammation Imaging and Radiation Dosimetry (2017)
- Contrast Media and Molecular Imaging
(A1 Refereed original research article in a scientific journal) - 18F-Labeling of Mannan for Inflammation Research with Positron Emission Tomography (2016)
- ACS Medicinal Chemistry Letters
(A1 Refereed original research article in a scientific journal)



