PhD Francisco Lopez Picon - UTU Research Portal

Francisco Lopez Picon
PhD

Turku PET Centre (Independent units)

francisco.lopez@utu.fi

+358 29 450 3840

+358 50 356 2885

Tykistökatu 6

Turku

Office: 4032

ORCID identifier: https://orcid.org/0000-0002-3871-1735

Turku PET Centre - Preclinical Unit

Areas of expertise

Preclinical PET imaging, Neuropharmacology, Animal models of CNS diseases.

Publications

1 of 3

Comparison of Automatic Segmentation and Preprocessing Approaches for Dynamic Total-Body 3D Pet Images with Different Pet Tracers (2025)
- Journal of Imaging Informatics in Medicine
Jaakkola, Maria K.; Rivera Pineda, Marcela Xiomara; Diaz, Rafael; Rantala, Maria; Jalo, Anna; Karpijoki, Henri; Saari, Teemu; Maaniitty, Teemu; Keller, Thomas; Louhi, Heli; Wahlroos, Saara; Haaparanta-Solin, Merja; Solin, Olof; Hentila, Jaakko; Helin, Jatta S.; Nissinen, Tuuli A.; Eskola, Olli; Rajander, Johan; Knuuti, Juhani; Virtanen, Kirsi A.; Hannukainen, Jarna C.; Lopez-Picon, Francisco; Klen, Riku
(A1 Refereed original research article in a scientific journal)
Evaluation of PET imaging as a tool for detecting neonatal hypoxic-ischemic encephalopathy in a preclinical animal model (2024)
- Experimental Neurology
Saha Emma, Shimochi Saeka, Keller Thomas, Eskola Olli, López-Picón Francisco, Rajander Johan, Löyttyniemi Eliisa, Forsback Sarita, Solin Olof, Grönroos Tove, Parikka Vilhelmiina
(A1 Refereed original research article in a scientific journal)
Evaluation of [18F]FMTEB in Sprague Dawley rats as a PET tracer for metabotropic glutamate receptor 5 (2023)
- Nuclear Medicine and Biology
Krzyczmonik Anna, Grafinger Katharina E., Keller Thomas, Pfeifer Lukas, Forsback Sarita, Haaparanta-Solin Merja, Gouverneur Veronique, López-Picón Francisco, Solin Olof
(A1 Refereed original research article in a scientific journal)
ImmunoPET Directed to the Brain: A New Tool for Preclinical and Clinical Neuroscience (2023)
- Biomolecules
Lucas de García Ángel, Lamminmäki Urpo, López-Picón R. Francisco
(A2 Refereed review article in a scientific journal )
Segmentation of Dynamic Total-Body [18F]-FDG PET Images Using Unsupervised Clustering (2023)
- International Journal of Biomedical Imaging
Jaakkola Maria K., Rantala Maria, Jalo Anna, Saari Teemu, Hentilä Jaakko, Helin Jatta S., Nissinen Tuuli A., Eskola Olli, Rajander Johan, Virtanen Kirsi A., Hannukainen Jarna C., López-Picón Francisco, Klén Riku
(A1 Refereed original research article in a scientific journal)
Biomarkers of the Endocannabinoid System in Substance Use Disorders (2022)
- Biomolecules
Navarrete Francisco, García-Gutiérrez María S., Gasparyan Ani, Navarro Daniela, López-Picón Francisco, Morcuende Álvaro, Femenia Teresa, Manzanares Jorge
(A2 Refereed review article in a scientific journal )
Dimethyl fumarate decreases short-term but not long-term inflammation in a focal EAE model of neuroinflammation (2022)
- EJNMMI Research
Vainio SK, Dickens AM, Matilainen M, Lopez-Picon FR, Aarnio R, Eskola O, Solin O, Anthony DC, Rinne JO, Airas L, Haaparanta-Solin M
(A1 Refereed original research article in a scientific journal)
Direct Comparison of [18F]F-DPA with [18F]DPA-714 and [11C]PBR28 for Neuroinflammation Imaging in the same Alzheimer’s Disease Model Mice and Healthy Controls (2022)
- Molecular Imaging and Biology
López-Picón Francisco R, Keller Thomas, Bocancea Diana, Helin Jatta S, Krzyczmonik Anna, Helin Semi, Damont Annelaure, Dollé Frédéric, Rinne Juha O, Haaparanta-Solin Merja, Solin Olof
(A1 Refereed original research article in a scientific journal)
ImmunoPET imaging of amyloid-beta in a rat model of Alzheimer’s disease with a bispecific, brain-penetrating fusion protein (2022)
- Translational Neurodegeneration
Bonvicini Gillian, Syvänen Stina, Andersson Ken G., Haaparanta-Solin Merja, Lopez-Picon Francisco, Sehlin Dag
(A1 Refereed original research article in a scientific journal)
Radiosynthesis and biological evaluation of [18F]CooP: a brain-homing peptide for imaging glioblastomas using positron emission tomography (2022)
- Nuclear Medicine and Biology
Abstracts of the International Symposium on Radiopharmaceutical Sciences iSRS 2022 Dillemuth Pyry, Auchynnikava Tatsiana, Ayo Abiodun, Kärnä Salli, Miner Maxwell, Liljenbäck Heidi, Lopez-Picon Francisco, Roivainen Anne, Laakkonen Pirjo, Airaksinen Anu, Li Xiang-Guo
(Other publication)
Intravenous transplantation of olfactory ensheathing cells reduces neuroinflammation after spinal cord injury via interleukin-1 receptor antagonist (2021)
- Theranostics
Zhang Lijian, Zhuang Xiaoqing, Kotitalo Päivi, Keller Thomas, Krzyczmonik Anna, Haaparanta-Solin Merja, Solin Olof, Forsback Sarita, Grönroos Tove J, Han Chunlei, López-Picón Francisco R, Xia Hechun
(A1 Refereed original research article in a scientific journal)
Longitudinal [18F]FDG and [13N]NH3 PET/CT imaging of brain and spinal cord in a canine hemisection spinal cord injury model (2021)
- NeuroImage: Clinical
Zhang Lijian, López-Picón Francisco R., Jia Yingqin, Chen Yao, Li Juan, Han Chunlei, Zhuang Xiaoqing, Xia Hechun
(A1 Refereed original research article in a scientific journal)
Prodromal neuroinflammatory, cholinergic and metabolite dysfunction detected by PET and MRS in the TgF344-AD transgenic rat model of AD: a collaborative multi-modal study (2021)
- Theranostics
Chaney Aisling M, Lopez-Picon Francisco R, Serrière Sophie, Wang Rui, Bochicchio Daniela, Webb Samuel D, Vandesquille Matthias, Harte Michael K, Georgiadou Christina, Lawrence Catherine, Busson Julie, Vercouillie Johnny, Tauber Clovis, Buron Frédérick, Routier Sylvain, Reekie Tristan, Snellman Anniina, Kassiou Michael, Rokka Johanna, Davies Karen E, Rinne Juha O, Salih Dervis A, Edwards Frances A, Orton Llwyd D, Williams Stephen R, Chalon Sylvie, Boutin Hervé
(A1 Refereed original research article in a scientific journal)
(S)-[18F]THK5117 brain uptake is associated with Aβ plaques and MAO-B enzyme in a mouse model of Alzheimer's disease (2021)
- Neuropharmacology
Alzghool Obada M, Rokka Johanna, López-Picón Francisco R, Snellman Anniina, Helin Jatta S, Okamura Nobuyuki, Solin Olof, Rinne Juha O, Haaparanta-Solin Merja
(A1 Refereed original research article in a scientific journal)
Comparison of high and low molar activity TSPO tracer [18F]F-DPA in a mouse model of Alzheimer’s disease (2020)
- Journal of Cerebral Blood Flow and Metabolism
Keller T., López-Picón F.R., Krzyczmonik A., Forsback S., Takkinen J.S., Rajander J., Teperi S., Dollé F., Rinne J.O., Haaparanta-Solin M., Solin O.
(A1 Refereed original research article in a scientific journal)
Evaluation of [F-18]F-DPA as a target for TSPO in head and neck cancer under normal conditions and after radiotherapy (2020)
- European Journal of Nuclear Medicine and Molecular Imaging
Tuominen Sanni, Keller Thomas, Petruk Nataliia, López-Picón Francisco, Eichin Dominik, Löyttyniemi Eliisa, Verhassel Alejandra, Rajander Johan, Sandholm Jouko, Tuomela Johanna, Grönroos Tove J.
(A1 Refereed original research article in a scientific journal)
Ruthenium-Mediated 18F-Fluorination and Preclinical Evaluation of a New CB1 Receptor Imaging Agent [18F]FPATPP (2020)
- ACS Chemical Neuroscience
Lahdenpohja S, Rajala N, Helin JS, Haaparanta-Solin M, Solin O, López-Picón FR, Kirjavainen A
(A1 Refereed original research article in a scientific journal)
A new perspective for advanced positron emission tomography-based molecular imaging in neurodegenerative proteinopathies (2019)
- Alzheimer's and Dementia
Daniela Perani, Leonardo Iaccarino, Adriaan A. Lammertsma, Albert D. Windhorst, Paul Edison, Ronald Boellaard, Oskar Hansson, Agneta Nordberg, Andreas H. Jacobs; for all partners of the IMBI Project
(A2 Refereed review article in a scientific journal )
Effect of genotype and age on cerebral [F-18]FDG uptake varies between transgenic APP(swe)-PS1(dE9) and Tg2576 mouse models of Alzheimer's disease (2019)
- Scientific Reports
Anniina Snellman, Jatta S. Takkinen, Francisco R. López-Picón, Olli Eskola, Olof Solin, Juha O. Rinne, Merja Haaparanta-Solin
(A1 Refereed original research article in a scientific journal)
In vivo characterization of a novel norepinephrine transporter PET tracer [18F]NS12137 in adult and immature Sprague-Dawley rats (2019)
- Theranostics
López-Picón F, Kirjavainen AK, Forsback S, Takkinen JS, Peters D, Haaparanta-Solin M, Solin O
(A1 Refereed original research article in a scientific journal)