PhD Pekka Rappu - UTU Research Portal

Pekka Rappu
PhD

- University Teacher,
Biochemistry (Department of Life Technologies)
- Docent,
Department of Life Technologies (Faculty of Technology)

pekrappu@utu.fi

+358 29 450 4785

Tykistökatu 6

Turku

ORCID identifier: https://orcid.org/0000-0002-5068-2842

Research group: Structure and Function of Collagen Receptor Integrins

Research

Extracellular matrix
Proteomics
Integrins

Teaching

Solu ja biomolekyylit - käytäntö
Molekyylibiologia - käytäntö

Publications

3 of 5

H-Ras activation and fibroblast-induced TGF-β signaling promote laminin-332 accumulation and invasion in cutaneous squamous cell carcinoma (2020)
- Matrix Biology
Siljamäki E, Rappu P, Riihilä P, Nissinen L, Kähäri VM, Heino J.
(A1 Refereed original research article in a scientific journal)
(2020)
- GuteLife
Tulkens Joeri, Vergauwen Glenn, Van Deun Jan, Geeurickx Edward, Dhondt Bert, Lippens Lien, De Scheerder Marie-Angelique, Miinalainen Ilkka, Rappu Pekka, De Geest Bruno G, Vandecasteele Katrien, Laukens Debby, Vandekerckhove Linos, Denys Hannelore, Vandesompele Jo, De Wever Olivier, Hendrix AnA1 Refereed original research article in a scientific journal
(2020) Extracellular Matrix Omics Valerio Izzi, Jarkko Koivunen, Pekka Rappu, Jyrki Heino, Taina Pihlajaniemi
(A3 Refereed book chapter or chapter in a compilation book)
Interaction between prostate cancer cells and prostate fibroblasts promotes accumulation and proteolytic processing of basement membrane proteinsUnravelling the proteomic landscape of extracellular vesicles in prostate cancer by density-based fractionation of urine (2020)
- Prostate
Ojalill M, Virtanen N, Rappu P, Siljamäki E, Taimen P, Heino JA1 Refereed original research article in a scientific journal
(2020)
- Journal of Extracellular VesiclesEssays in Biochemistry
Dhondt B, Geeurickx E, Tulkens J, Van Deun J, Vergauwen G, Lippens L, Miinalainen I, Rappu P, Heino J, Ost P, Lumen N, De Wever O, Hendrix A
(A1 Refereed original research article in a scientific journal)
FAK activity sustains intrinsic and acquired ovarian cancer resistance to platinum chemotherapy (2019)
Osterman CJD, Ozmadenci D, Kleinschmidt EG, Taylor KN, Barrie AM, Jiang SL, Bean LM, Sulzmaier FJ, Jean C, Tancioni I, Anderson K, Uryu S, Cordasco EA, Li J, Chen XL, Fu G, Ojalill M, Rappu P, Heino J, Mark AM, Xu GR, Fisch KM, Kolev VN, Weaver DT, Pachter JA, Gyorffy B, McHale MT, Connolly DC, Molinolo A, Stupack DG, Schlaepfer DD, Schlaepfer DD
(A1 Refereed original research article in a scientific journal)
Role of prolyl hydroxylation in the molecular interactions of collagens (2019)
Rappu P., Salo A., Myllyharju J., Heino J.
(A2 Refereed review article in a scientific journal )
Integrin α2β1 decelerates proliferation, but promotes survival and invasion of prostate cancer cells (2018)
- Oncotarget
Ojalill M., Parikainen M., Rappu P., Aalto E., Jokinen J., Virtanen N., Siljamäki E., Heino J.
(A1 Refereed original research article in a scientific journal)
Proline hydroxylation in collagen supports integrin binding by two distinct mechanismsThe composition of prostate core matrisome in vivo and in vitro unveiled by mass spectrometric analysis (2018)
- Journal of Biological Chemistry
Kalle H. Sipilä, Kati Drushinin, Pekka Rappu, Johanna Jokinen, Tiina A. Salminen, Antti M. Salo, Jarmo Käpylä, Johanna Myllyharju, Jyrki Heino
(A1 Refereed original research article in a scientific journal)
(2018)
- Prostate
Marjaana Ojalill, Pekka Rappu, Elina Siljamäki, Pekka Taimen, Peter Boström, Jyrki Heino
(A1 Refereed original research article in a scientific journal)