Janne Leivo
Ph.D.
jpleiv@utu.fi Kiinamyllynkatu 10 Turku Työhuone: D6048 ORCID-tunniste: https://orcid.org/0000-0002-1032-6667 |
Antibody engineering; Immunoassays; Extracellular vesicles; Diagnostics
I am a senior researcher fellow and InFLAMES Group leader at the Department of Life Technologies and FICAN West Cancer Centre. My group bridges novel biomarker concepts, extracellular vesicle analytics, and advanced immunoassay technologies to enable more sensitive and specific diagnostics.
The primary focus of our group is to design and validate novel biomarker concepts for early cancer detection and precision disease management. We have established a biomarker development pipeline based on glycovariants of various tumor markers and extracellular vesicles.
Our research is in the interface of basic and translational research, combining biomarker discovery, antibody and assay development, and clinical validation to address the clinical need for the detection of the most common solid cancers.
- Aberrantly glycosylated PSMA in urine as a potential marker for prostate cancer (2026)
- Clinica Chimica Acta
(A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä ) - Cell-Based Immunization Combined with Single-Round Cell Panning Enables Discovery of PSMA-Targeting Nanobodies from Phage Display Libraries (2026)
- Biomolecules
(A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä ) - Development of an Anti-Immunocomplex Antibody and Non-competitive Immunoassay for the Detection of Testosterone (2026)
- Analytical Chemistry
(A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä ) - Molecular Characterization of Extracellular Vesicles From Human B Cell Lymphomas: Methodological Comparison to Vesicles From Patient Serum (2026)
- Journal of Extracellular Biology
(A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä ) - Pre- and postoperative expression of circulating CEACAM1 and CEACAM6 using a nanoparticle-supported, lectin-specific assay detected in serum from patients with colorectal cancer (2026)
- Scandinavian Journal of Gastroenterology
(A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä ) - Designing nanoparticle-based bioaffinity assays for the detection of extracellular vesicles (2025)
- Nanomedicine
(B1 Vertaisarvioitu muu artikkeli (esim. pääkirjoitus, letter, comment) tieteellisessä lehdessä) - Evaluation of Integrin Glycovariants as Biomarkers of Metastasis, Invasion, and Therapy Stratification in Head and Neck Squamous Cell Carcinoma (2025)
- Cancer Medicine
(A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä ) - High‐Sensitivity Detection of Urinary Extracellular Vesicles With Upconverting Nanoparticle‐Based Lateral Flow Immunoassay (2025)
- Journal of Extracellular Biology
(A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä ) - MUC1 and glycan probing of CA19-9 captured biomarkers from cyst fluids and serum provides enhanced recognition of ovarian cancer (2025)
- Scientific Reports
(A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä ) - Roadblocks of Urinary EV Biomarkers: Moving Toward the Clinic (2025)
- Journal of Extracellular Vesicles
(A2 Vertaisarvioitu katsausartikkeli tieteellisessä lehdessä)



