Ph.D. Janne Leivo - UTU Research Portal

Janne Leivo
Ph.D.

- Senior Research Fellow,
Biotechnology (Department of Life Technologies)
- Docent,
Department of Life Technologies (Faculty of Technology)
- ,
InFLAMES Flagship (Faculty of Medicine)

jpleiv@utu.fi

Kiinamyllynkatu 10

Turku

Office: D6048

ORCID identifier: https://orcid.org/0000-0002-1032-6667

Lab website

Google Scholar

FICan West Cancer Research Laboratory

Areas of expertise

Antibody engineering; Immunoassays; Extracellular vesicles; Diagnostics

Biography

I am a senior researcher fellow and InFLAMES Group leader at the Department of Life Technologies and FICAN West Cancer Centre. My group bridges novel biomarker concepts, extracellular vesicle analytics, and advanced immunoassay technologies to enable more sensitive and specific diagnostics.

Research

The primary focus of our group is to design and validate novel biomarker concepts for early cancer detection and precision disease management. We have established a biomarker development pipeline based on glycovariants of various tumor markers and extracellular vesicles.

Our research is in the interface of basic and translational research, combining biomarker discovery, antibody and assay development, and clinical validation to address the clinical need for the detection of the most common solid cancers.

Publications

1 of 4

Aberrantly glycosylated PSMA in urine as a potential marker for prostate cancer (2026)
- Clinica Chimica Acta
Khan, Misba; Islam, Md. Khirul; Taimen, Pekka; Boström, Peter J.; Lamminmäki, Urpo; Leivo, Janne
(A1 Refereed original research article in a scientific journal)
Cell-Based Immunization Combined with Single-Round Cell Panning Enables Discovery of PSMA-Targeting Nanobodies from Phage Display Libraries (2026)
- Biomolecules
Yang, Tong; Veldhoven-Zweistra, Joke; Ligtenberg, Maarten; Erkens, Sigrun; Vredenbregt-van den Berg, Mirella; Jansen, Rick; Chames, Patrick; Bindels, Eric M. J.; Ahmadi, Khadijeh; Bangma, Chris H.; Kalsbeek, Anton M. F.; Leivo, Janne; Lumen, Nicolaas; Werken, Harmen J. G. Van De; Weerden, Wytske M. Van; Kavousipour, Soudabeh; Tooyserkani, Raheleh; Jenster, Guido
(A1 Refereed original research article in a scientific journal)
Development of an Anti-Immunocomplex Antibody and Non-competitive Immunoassay for the Detection of Testosterone (2026)
- Analytical Chemistry
Bäckström, Ida; Lamminmäki, Urpo; Juntunen, Etvi; Leivo, Janne
(A1 Refereed original research article in a scientific journal)
Molecular Characterization of Extracellular Vesicles From Human B Cell Lymphomas: Methodological Comparison to Vesicles From Patient Serum (2026)
- Journal of Extracellular Biology
Badal, Md Nasir Uddin; Koivula, Tiia; Islam, Md Khirul; Lehtinen, Laura; Kauko, Otto; Leivo, Janne; Heinonen, Ilkka; Hämälistö, Saara
(A1 Refereed original research article in a scientific journal)
Pre- and postoperative expression of circulating CEACAM1 and CEACAM6 using a nanoparticle-supported, lectin-specific assay detected in serum from patients with colorectal cancer (2026)
- Scandinavian Journal of Gastroenterology
Kanani, Arezo; Alexeeva, Marina; Vinod, Rufus; Pettersson, Kim; Leivo, Janne; Søreide, Kjetil
(A1 Refereed original research article in a scientific journal)
Designing nanoparticle-based bioaffinity assays for the detection of extracellular vesicles (2025)
- Nanomedicine
Islam, Md. Khirul; Mahmud, Imran; Leivo, Janne
(B1 Other refereed article (e.g., editorial, letter, comment) in a scientific journal)
Evaluation of Integrin Glycovariants as Biomarkers of Metastasis, Invasion, and Therapy Stratification in Head and Neck Squamous Cell Carcinoma (2025)
- Cancer Medicine
Routila, Erica; Salminen, Sadie; Mahran, Randa; Toriseva, Mervi; Irjala, Heikki; Haapio, Eeva; Kytö, Eero; Ventelä, Sami; Pettersson, Kim; Routila, Johannes; Gidwani, Kamlesh; Leivo, Janne
(A1 Refereed original research article in a scientific journal)
High‐Sensitivity Detection of Urinary Extracellular Vesicles With Upconverting Nanoparticle‐Based Lateral Flow Immunoassay (2025)
- Journal of Extracellular Biology
Islam, Md. Khirul; Mahmud, Imran; Ali, Klinton; Salminen, Teppo; Taimen, Pekka; Boström, Peter J.; Leivo, Janne; Lamminmäki, Urpo; Martiskainen, Iida
(A1 Refereed original research article in a scientific journal)
MUC1 and glycan probing of CA19-9 captured biomarkers from cyst fluids and serum provides enhanced recognition of ovarian cancer (2025)
- Scientific Reports
Afrin Ruma, Shamima; Vinod, Rufus; Jain, Shruti; Huhtinen, Kaisa; Hynninen, Johanna; Leivo, Janne; Pettersson, Kim; Sundfeldt, Karin; Gidwani, Kamlesh
(A1 Refereed original research article in a scientific journal)
Roadblocks of Urinary EV Biomarkers: Moving Toward the Clinic (2025)
- Journal of Extracellular Vesicles
Droste, Marvin; Puhka, Maija; van Royen, Martin E.; Ng, Monica S. Y.; Blijdorp, Charles; Alvarez-Llamas, Gloria; Borràs, Francesc E.; Buescher, Anja K.; Bussolati, Benedetta; Dear, James W.; Falcón-Pérez, Juan M.; Giebel, Bernd; Grange, Cristina; Hoorn, Ewout J.; Leivo, Janne; Lenassi, Metka; Llorente, Alicia; Lucien, Fabrice; Mertens, Inge; Mischak, Harald; Pink, Desmond; Tertel, Tobias; Tiwari, Swasti; Vizio, Dolores Di; Yuen, Peter S. T.; Zarovni, Natasa; Jenster, Guido; Burger, Dylan; Martens-Uzunova, Elena S.; Erdbrügger, Uta
(A2 Refereed review article in a scientific journal )