Janne Leivo
Ph.D.
jpleiv@utu.fi Kiinamyllynkatu 10 Turku Office: D6048 ORCID identifier: https://orcid.org/0000-0002-1032-6667 |
Areas of expertise
Antibody engineering; Immunoassays; Extracellular vesicles; Diagnostics
Antibody engineering; Immunoassays; Extracellular vesicles; Diagnostics
Biography
I am a senior researcher fellow and InFLAMES Group leader at the Department of Life Technologies and FICAN West Cancer Centre. My group bridges novel biomarker concepts, extracellular vesicle analytics, and advanced immunoassay technologies to enable more sensitive and specific diagnostics.
Research
The primary focus of our group is to design and validate novel biomarker concepts for early cancer detection and precision disease management. We have established a biomarker development pipeline based on glycovariants of various tumor markers and extracellular vesicles.
Our research is in the interface of basic and translational research, combining biomarker discovery, antibody and assay development, and clinical validation to address the clinical need for the detection of the most common solid cancers.
Publications 
2 of 2
- A Nanoparticle-Based Approach for the Detection of Extracellular Vesicles (2019)
- Scientific Reports
(A1 Refereed original research article in a scientific journal) - Detection of Food Taints and Contaminants Using Novel Engineered Antibodies (2019) Rapid Antibody-based Technologies in Food Analysis Leivo J., Lamminmäki U.
(A3 Refereed book chapter or chapter in a compilation book) - Development of anti-immunocomplex specific antibodies and non-competitive time-resolved fluorescence immunoassay for the detection of estradiol (2019)
- Analytical and Bioanalytical Chemistry
(A1 Refereed original research article in a scientific journal) - Noncompetitive Chromogenic Lateral-Flow Immunoassay for Simultaneous Detection of Microcystins and Nodularin (2019)
- Biosensors
(A1 Refereed original research article in a scientific journal) - Accelerating food safety and quality control: The use of antibody engineering techniques in the detec-tion of low-molecular weight food contaminants (2016) Leivo Janne
(G5 Article dissertation ) - Development of recombinant antibody-based enzyme-linked immunosorbent assay (ELISA) for the detection of skatole (2016)
- Analytical Biochemistry
(A1 Refereed original research article in a scientific journal) - Role of lectin microarrays in cancer diagnosis (2016)
- Proteomics
(A2 Refereed review article in a scientific journal ) - Immuno-based detection of extracellular vesicles in urine as diagnostic marker for prostate cancer (2015)
- International Journal of Cancer
(A1 Refereed original research article in a scientific journal) - Multiresidue Detection of Fluoroquinolones: Specificity Engineering of a Recombinant Antibody with Oligonucleotide-Directed Mutagenesis (2013)
- Journal of Agricultural and Food Chemistry
(A1 Refereed original research article in a scientific journal) - Directed antibody-engineering techniques and their applications in food immunoassays (2011)
- Trends in Analytical Chemistry
(A1 Refereed original research article in a scientific journal) - Engineering of a broad-specificity antibody: Detection of eight fluoroquinolone antibiotics simultaneously (2011)
- Analytical Biochemistry
(A1 Refereed original research article in a scientific journal) - Synthetic single-framework antibody library integrated with rapid affinity maturation by V-L shuffling (2011)
- Protein Engineering, Design and Selection
(A1 Refereed original research article in a scientific journal) - Development of an optical surface plasmon resonance biosensor assay for (fluoro)quinolones in egg, fish, and poultry meat (2008)
- Analytica Chimica Acta
(A1 Refereed original research article in a scientific journal)
UTU Research Portal