Refereed review article in scientific journal (A2)

Why mammalian cell surface proteins are glycoproteins




List of AuthorsGahmberg CG, Tolvanen M

Publication year1996

JournalTrends in Biochemical Sciences

Journal name in sourceTrends in biochemical sciences

Journal acronymTrends Biochem Sci

Volume number21

Issue number8

Start page308

End page11

ISSN0968-0004


Abstract
Most proteins presented at the external surface of mammalian cells contain carbohydrate. The reason for this is not fully understood, but recent work has shown that such carbohydrate has two major functions. Inside the cell, it helps proteins fold and assembly correctly in the endoplasmic reticulum, and it might also act as a signal for the correct migration of glycoproteins. Outside the cell, it provides specific recognition structures for interaction with a variety of external ligands.


Last updated on 2023-28-12 at 14:00