A2 Refereed review article in a scientific journal
Extrahypothalamic Control of Energy Balance and Its Connection with Reproduction: Roles of the Amygdala
Authors: Pineda Rafael, Torres Encarnacion, Tena-Sempere Manuel
Publisher: MDPI
Publishing place: Basel
Publication year: 2021
Journal:: Metabolites
Journal name in source: METABOLITES
Journal acronym: METABOLITES
Article number: ARTN 837
Volume: 11
Issue: 12
Number of pages: 12
eISSN: 2218-1989
DOI: https://doi.org/10.3390/metabo11120837
Web address : https://doi.org/10.3390/metabo11120837
Self-archived copy’s web address: https://research.utu.fi/converis/portal/detail/Publication/68743059
Body energy and metabolic homeostasis are exquisitely controlled by multiple, often overlapping regulatory mechanisms, which permit the tight adjustment between fuel reserves, internal needs, and environmental (e.g., nutritional) conditions. As such, this function is sensitive to and closely connected with other relevant bodily systems, including reproduction and gonadal function. The aim of this mini-review article is to summarize the most salient experimental data supporting a role of the amygdala as a key brain region for emotional learning and behavior, including reward processing, in the physiological control of feeding and energy balance. In particular, a major focus will be placed on the putative interplay between reproductive signals and amygdala pathways, as it pertains to the control of metabolism, as complementary, extrahypothalamic circuit for the integral control of energy balance and gonadal function.
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