A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä

Consumption of healthcare services and antibiotics in patients with presumed disseminated Lyme borreliosis before and after evaluation of an infectious disease specialist




TekijätKortela Elisa, Kanerva Mari J, Kurkela Satu, Oksi Jarmo, Koivisto Mari, Järvinen Asko

KustantajaELSEVIER GMBH

Julkaisuvuosi2022

JournalTicks and Tick-borne Diseases

Tietokannassa oleva lehden nimiTICKS AND TICK-BORNE DISEASES

Lehden akronyymiTICKS TICK-BORNE DIS

Artikkelin numeroARTN 101854

Vuosikerta13

Sivujen määrä6

ISSN1877-959X

DOIhttps://doi.org/10.1016/j.ttbdis.2021.101854

Rinnakkaistallenteen osoitehttps://research.utu.fi/converis/portal/detail/Publication/68525717


Tiivistelmä
Our objective was to study the consumption of healthcare services and antibiotics in patients with suspicion of disseminated Lyme borreliosis (LB) before and after consultation of an infectious disease specialist. We evaluated retrospectively all presumed disseminated LB patients (n = 256) with a referral to the Department of Infectious Diseases (DID) in Helsinki University Hospital in 2013. Medical records from all healthcare providers in the area were reviewed and the number of physician contacts because of symptoms leading to LB suspicion and antimicrobial purchases were calculated 1 year before and after consultation or treatment at the DID. Patients were divided into three groups according to certainty of LB: unlikely, possible or probable/definite LB. The number of healthcare contacts 1 year before referral was higher among 121 patients with unlikely LB (6; interquartile range [IQR] 3-10), than 65 possible (4; IQR 2.5-7; p = 0.018) or 66 probable/definite LB patients (4; IQR 2.8-7; p = 0.010). The median number of contacts to healthcare during one year after consultation or treatment was 3 (IQR 0.5-7), 1 (IQR 0-3) and 0.5 (IQR 0-2.3), respectively, with a statistically significant difference between the groups (p<0.001). Antibiotics were purchased by 151 (60%) patients one year before referral and by 127 (50%) patients year after consultation or treatment at DID without statistically significant difference between groups with different LB certainty. These antibiotic purchases do not include the treatments prescribed by infectious disease specialists. In the case of 27 patients, an antimicrobial treatment was recommended in the consultation reply. In conclusion, patients with unlikely LB used more healthcare services than patients with possible or probable/definite LB. Antimicrobial consumption was similar between groups of different LB certainty.

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