A1 Refereed original research article in a scientific journal

BioCPR–A Tool for Correlation Plots




AuthorsFey Vidal, Jambulingam Dhanaprakash, Sara Henri, Heron Samuel, Sipeky Csilla, Schleutker Johanna

PublisherMDPI

Publication year2021

JournalData

Journal name in sourceData

Article number97

Volume6

Issue9

ISSN2306-5729

DOIhttps://doi.org/10.3390/data6090097

Self-archived copy’s web addresshttps://research.utu.fi/converis/portal/detail/Publication/67435398


Abstract

A gene is a sequence of DNA bases through which genetic information is passed on to the next generation. Most genes encode for proteins that ultimately control cellular function. Understanding the interrelation between genes without the application of statistical methods can be a daunting task. Correlation analysis is a powerful approach to determine the strength of association between two variables (e.g., gene-wise expression). Moreover, it becomes essential to visualize this data to establish patterns and derive insight. The most common method for gene expression visualization is to use correlation heatmaps in which the colors of the plot represent strength of co-expression. In order to address this requirement, we developed a visualization tool called BioCPR: Biological Correlation Plots in R. This tool performs both correlation analysis and subsequent visualization in the form of an interactive heatmap, improving both usability and interpretation of the data. BioCPR is an R Shiny-based application and can be run locally in Rstudio or a web browser.


Downloadable publication

This is an electronic reprint of the original article.
This reprint may differ from the original in pagination and typographic detail. Please cite the original version.





Last updated on 2024-26-11 at 11:33